ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Products of "ALK"
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Zotizalkib
CAS:TPX-0131: potent, selective, CNS-ready, oral ALK inhibitor (WT IC50: 1.4nM, G1202R/L1196M IC50: 0.3nM) with robust antitumor effects.Formula:C21H20F3N5O3Purity:98.7%Color and Shape:SolidMolecular weight:447.41SB 525334
CAS:SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).Formula:C21H21N5Purity:98.39% - ≥95%Color and Shape:SolidMolecular weight:343.42Itacnosertib
CAS:Itacnosertib (TP-0184) is an orally available ACRV1 (ALK-2), FLT3 and JAK2 inhibitor that inhibits the growth of tumor cells,antitumor and antileukemic.Formula:C26H28N8OPurity:99.38%Color and Shape:SolidMolecular weight:468.55GW788388
CAS:GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.Formula:C25H23N5O2Purity:98.03% - 98.79%Color and Shape:SolidMolecular weight:425.48R-268712
CAS:R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formula:C20H18FN5OPurity:99.61%Color and Shape:SolidMolecular weight:363.39Ref: TM-T16708
1mg47.00€5mg87.00€10mg137.00€25mg264.00€50mg399.00€100mg567.00€200mg805.00€1mL*10mM (DMSO)97.00€5-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formula:C12H9N3SPurity:97%Color and Shape:SolidMolecular weight:227.29Ref: TM-T50042
2mg46.00€5mg64.00€10mg95.00€25mg145.00€50mg212.00€100mg319.00€200mg455.00€1mL*10mM (DMSO)64.00€ALK2-IN-2
CAS:ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.Formula:C28H27N5O2SPurity:99.55%Color and Shape:SolidMolecular weight:497.61Ref: TM-T10287
1mg62.00€5mg135.00€10mg207.00€25mg325.00€50mg449.00€100mg620.00€200mg843.00€1mL*10mM (DMSO)149.00€A 83-01 sodium salt
CAS:A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 nM.Formula:C25H19N5NaSColor and Shape:SolidMolecular weight:444.51CEP-28122
CAS:CEP-28122 is a highly potent and selective orally active ALK inhibitor.Formula:C28H35ClN6O3Purity:100%Color and Shape:SolidMolecular weight:539.07Vactosertib Hydrochloride
CAS:Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an ALK5 inhibitor, a TGF-β receptor I inhibitor with antimetastatic and anticancer effects.Formula:C22H19ClFN7Purity:98.03%Color and Shape:SolidMolecular weight:435.89Ref: TM-T15262
1mg35.00€5mg74.00€10mg97.00€25mg169.00€50mg255.00€100mg395.00€200mg563.00€1mL*10mM (DMSO)81.00€N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS:Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.Formula:C22H18BrN7Purity:99.27%Color and Shape:SolidMolecular weight:460.33Ref: TM-T9837
1mg87.00€5mg192.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)226.00€K02288
CAS:K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.Formula:C20H20N2O4Purity:98% - 99.81%Color and Shape:SolidMolecular weight:352.38
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