c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
Products of "c-Fms"
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Plonmarlimab
CAS:Plonmarlimab(TJ003234) is an anti-GM-CSF monoclonal antibody with potential antiviral activity for the study of immune disorders and novel coronavirus infectionColor and Shape:LiquidKi20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:97.16% - 99.37%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg47.00€5mg96.00€10mg154.00€25mg283.00€50mg464.00€100mg740.00€200mg1,008.00€1mL*10mM (DMSO)96.00€Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.Formula:C21H21FN6OPurity:99.66% - 99.78%Color and Shape:SolidMolecular weight:392.43Ref: TM-T6289
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg328.00€200mg490.00€500mg783.00€1mL*10mM (DMSO)50.00€CSF1R Protein, Human, Recombinant (His & Avi)
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Nampt-IN-1
CAS:Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Formula:C20H25N3O5SPurity:96.82% - 99.4%Color and Shape:SolidMolecular weight:419.49Ref: TM-T4376
1mg39.00€2mg52.00€5mg84.00€10mg137.00€25mg259.00€50mg432.00€100mg638.00€1mL*10mM (DMSO)92.00€Anumigilimab
CAS:Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.Purity:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Color and Shape:LiquidMolecular weight:143.86 kDaPexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purity:98.34% - 99.51%Color and Shape:SolidMolecular weight:417.81Ref: TM-T2115
5mg48.00€10mg62.00€25mg95.00€50mg120.00€100mg154.00€200mg202.00€500mg350.00€1mL*10mM (DMSO)52.00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:96.25%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg90.00€5mg187.00€10mg305.00€25mg520.00€50mg748.00€100mg1,026.00€1mL*10mM (DMSO)215.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:98.34% - 99.62%Color and Shape:SolidMolecular weight:419.48CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.c-Fms-IN-14
CAS:c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Formula:C26H24N6OPurity:98%Color and Shape:SolidMolecular weight:436.51PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Formula:C26H30Cl2N6O4Purity:98.65%Color and Shape:SolidMolecular weight:561.46Ref: TM-TQ0015
1mg81.00€2mg105.00€5mg170.00€10mg305.00€25mg520.00€50mg748.00€100mg1,026.00€1mL*10mM (DMSO)212.00€Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Formula:C20H22N4O3SPurity:97.43% - 99.82%Color and Shape:SolidMolecular weight:398.48Ref: TM-T6119
1mg37.00€5mg79.00€10mg111.00€25mg172.00€50mg216.00€100mg378.00€500mg868.00€1mL*10mM (DMSO)87.00€CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formula:C20H20FN7O2Purity:99.29%Color and Shape:SolidMolecular weight:409.42Pyrithyldione
CAS:Pyrithyldione is a sedative-hypnotic agent known to potentially induce agranulocytosis.Formula:C9H13NO2Color and Shape:SolidMolecular weight:167.21Anti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Color and Shape:Odour LiquidcFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFormula:C23H20N4OPurity:99.80%Color and Shape:SolidMolecular weight:368.43Ref: TM-T5586
1mg49.00€2mg65.00€5mg97.00€10mg154.00€25mg255.00€50mg376.00€100mg547.00€1mL*10mM (DMSO)106.00€Anti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Color and Shape:Odour LiquidOSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Ref: TM-T2624
1mg51.00€5mg93.00€10mg144.00€25mg263.00€50mg424.00€100mg612.00€200mg873.00€1mL*10mM (DMSO)97.00€Enrupatinib
CAS:Enrupatinib is an inhibitor of the colony stimulating factor 1 receptor (CSF1R), exhibiting antitumor activity.Formula:C27H26N6O3Color and Shape:SolidMolecular weight:482.53
