c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
Products of "c-Fms"
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Anti-CSF1R Antibody (7V18)
Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.Color and Shape:Odour LiquidSotuletinib dihydrochloride
CAS:Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.Formula:C20H24Cl2N4O3SPurity:98%Color and Shape:SolidMolecular weight:471.4c-Fms-IN-9
CAS:c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 <0.01μM and 0.1-1μM, from patent WO2014145023A1.Formula:C21H23N7O2Purity:98%Color and Shape:SolidMolecular weight:405.45cFMS Receptor Inhibitor IV
CAS:cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.Formula:C22H26N4O2Purity:99.73%Color and Shape:SolidMolecular weight:378.47AZ304
CAS:AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Formula:C27H25N5O2Purity:99.82%Color and Shape:SolidMolecular weight:451.52CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:SDS-PAGE: 97.7%; SEC-HPLC: 99.7%Color and Shape:Lyophilized PowderMolecular weight:56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98Ref: TM-T6930
10mg52.00€25mg90.00€50mg96.00€100mg140.00€200mg229.00€500mg359.00€1mL*10mM (DMSO)52.00€Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formula:C23H25N7O2Purity:99.05% - 99.57%Color and Shape:SolidMolecular weight:431.49Ref: TM-T10652
1mg92.00€5mg188.00€10mg311.00€25mg533.00€50mg727.00€100mg938.00€1mL*10mM (DMSO)215.00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg50.00€10mg85.00€25mg126.00€50mg188.00€100mg274.00€200mg505.00€500mg815.00€1mL*10mM (DMSO)52.00€c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Formula:C23H30N6OPurity:99.92%Color and Shape:SolidMolecular weight:406.52Ref: TM-T10649
1mg50.00€5mg111.00€10mg170.00€25mg279.00€50mg378.00€100mg552.00€1mL*10mM (DMSO)116.00€CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:31.1 kDa (predicted)Anti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Color and Shape:Odour LiquidGW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Formula:C20H22N4O3Purity:100% - 99.86%Color and Shape:SolidMolecular weight:366.41c-Fms-IN-1
CAS:c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Formula:C22H27N5O2Purity:99.88%Color and Shape:SolidMolecular weight:393.48CSF1R-IN-3
CAS:CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Formula:C30H38N8O4Purity:97.31%Color and Shape:SolidMolecular weight:574.67Ref: TM-T64066
1mg106.00€5mg259.00€10mg378.00€25mg702.00€50mg1,026.00€100mg1,473.00€1mL*10mM (DMSO)325.00€CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formula:C25H20F3N5O2Purity:97.02% - 98.56%Color and Shape:SolidMolecular weight:479.45Ref: TM-T10894
1mg94.00€5mg210.00€10mg325.00€25mg550.00€50mg787.00€100mg1,093.00€200mg1,454.00€1mL*10mM (DMSO)230.00€CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Color and Shape:Lyophilized PowderMolecular weight:83.04 kDa (predicted); 110.87 kDa (reducing conditions)Anti-CSF1R Antibody (1R707)
Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.Color and Shape:Odour LiquidAZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Formula:C23H27FN6O3Purity:98.01% - 99.09%Color and Shape:SolidMolecular weight:454.5Ref: TM-T14380
1mg52.00€5mg116.00€10mg170.00€25mg305.00€50mg442.00€100mg615.00€200mg832.00€1mL*10mM (DMSO)134.00€IACS-9439
CAS:IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Formula:C23H26ClN7O3SPurity:98%Color and Shape:SolidMolecular weight:516.02
