VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 97.89%Color and Shape:SolidMolecular weight:491.39Ref: TM-TQ0166
1mg107.00€2mg156.00€5mg236.00€10mg457.00€25mg750.00€50mg1,026.00€1mL*10mM (DMSO)255.00€ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Formula:C19H16BrFN6O2Purity:99.12%Color and Shape:SolidMolecular weight:459.27Ref: TM-T5475
1mg85.00€5mg183.00€10mg275.00€25mg437.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)185.00€BMS-2
CAS:BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formula:C25H16F2N4O3Purity:98.33%Color and Shape:SolidMolecular weight:458.42GW806742X
CAS:GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.Formula:C25H22F3N7O4SPurity:98.30%Color and Shape:SolidMolecular weight:573.552H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
CAS:Formula:C15H14N2OPurity:98%Color and Shape:SolidMolecular weight:238.2845SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formula:C18H22N4O4Purity:97.52% - 99.68%Color and Shape:SolidMolecular weight:358.39Ref: TM-T6012
1mg35.00€5mg73.00€10mg113.00€25mg226.00€50mg344.00€100mg515.00€200mg620.00€1mL*10mM (DMSO)86.00€CP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormula:C24H27N5O2Purity:99.62% - 99.88%Color and Shape:SolidMolecular weight:417.5Ref: TM-T6091
1mg52.00€2mg66.00€5mg96.00€10mg180.00€25mg354.00€50mg540.00€100mg778.00€500mg1,605.00€1mL*10mM (DMSO)114.00€EOC317
CAS:EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).Formula:C27H26F5N7O3Purity:98.00% - 99.26%Color and Shape:SolidMolecular weight:591.53Ref: TM-T4318
1mg117.00€2mg172.00€5mg248.00€10mg418.00€25mgTo inquire50mgTo inquire100mgTo inquire1mL*10mM (DMSO)324.00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:98.31% - ≥95%Color and Shape:SolidMolecular weight:284.31VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:24.8 kDa (predicted)JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurity:99.43% - 99.96%Color and Shape:SolidMolecular weight:649.76Ref: TM-T5001
5mg43.00€10mg57.00€25mg71.00€50mg85.00€100mg105.00€200mg164.00€500mg316.00€1mL*10mM (DMSO)63.00€(Rac)-SAR131675
CAS:(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.Formula:C18H22N4O4Purity:98.34% - 99.1%Color and Shape:SolidMolecular weight:358.39NVP-BHG 712
CAS:Formula:C26H20F3N7OPurity:>95.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:503.49Anti-VEGFR2/KDR Antibody-APC (1T318)
Anti-VEGFR2/KDR Antibody-APC (1T318) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (1T318) can be used in FCM.Color and Shape:Odour LiquidVEGFR-2-IN-9
CAS:VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Formula:C23H25N3O3Purity:97.19%Color and Shape:SolidMolecular weight:391.46Brolucizumab
CAS:Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment exhibiting low picomolar affinity (K D = 1.05 pM), utilized for cancer research [1] [2].Purity:98%Color and Shape:LiquidMulti-kinase inhibitor 3
CAS:Multi-kinase inhibitor 3 (compound 12) is an orally active and effective multikinase (multikinase) inhibitor, demonstrating potent IC50 values against FLT1/VEGFR1, KDR/VEGFR2, FLT4/VEGFR3, FLT3, PDGFRα, and PDGFRβ, at 1.59, 1.23, 1.19, 0.59, 0.22, and 1.15 nM respectively. This compound exhibits anti-proliferative and anticancer activities.Formula:C26H26N6O2Color and Shape:SolidMolecular weight:454.52JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.35% - 99.41%Color and Shape:SolidMolecular weight:466.33Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:98.44% - 99.54%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg51.00€10mg79.00€25mg129.00€50mg213.00€100mg358.00€200mg535.00€500mg843.00€1mL*10mM (DMSO)57.00€Tanshinone IIA
CAS:Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.Formula:C19H18O3Purity:100% - 99.36%Color and Shape:Cherry CrystalMolecular weight:294.34Anti-VEGFR2/KDR Antibody (4B612)
Anti-VEGFR2/KDR Antibody (4B612) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (4B612) can be used in ELISA(Cap),FCM.Color and Shape:Odour LiquidIcrucumab
CAS:Icrucumab, a humanized antibody, inhibits VEGFR-1 and shows antitumor effects, tested in metastatic colon cancer.Purity:> 95%Color and Shape:LiquidMolecular weight:150 kDaDMH4
CAS:DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Formula:C24H24N4O2Purity:98.68%Color and Shape:SolidMolecular weight:400.47(Z)-Semaxinib
CAS:(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition forFormula:C15H14N2OPurity:96.09% - ≥95%Color and Shape:SolidMolecular weight:238.28Ref: TM-T2496
1mg57.00€5mg111.00€10mg188.00€25mg331.00€50mg568.00€100mg695.00€200mg948.00€1mL*10mM (DMSO)144.00€Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Formula:C15H10O6Purity:98% - 98%Color and Shape:SolidMolecular weight:286.24VEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formula:C20H21N7O2SPurity:99.01%Color and Shape:SolidMolecular weight:423.49N-Desethylsunitinib hydrochloride
CAS:N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Formula:C20H24ClFN4O2Purity:99.42%Color and Shape:SolidMolecular weight:406.88Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formula:C28H24FN3O5Purity:99.59% - 99.88%Color and Shape:SolidMolecular weight:501.51VEGFR-2/c-Met-IN-1
VEGFR-2/c-Met-IN-1 is a dual inhibitor targeting VEGFR-2 and c-Met with respective IC50 values of 138 nM and 74 nM, demonstrating antitumor activity [1].Purity:98%Color and Shape:Odour SolidAnti-VEGFR2/KDR Antibody-FITC (5U735)
Anti-VEGFR2/KDR Antibody-FITC (5U735) is a FITC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-FITC (5U735) can be used in FCM.Color and Shape:Odour LiquidSakuranetin
CAS:Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effectsFormula:C16H14O5Purity:98.54% - 99.65%Color and Shape:SolidMolecular weight:286.28SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Formula:C16H13NO2Purity:99.45% - 99.55%Color and Shape:SolidMolecular weight:251.28VEGFR-2-IN-65
CAS:VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.Formula:C21H18N2O3Color and Shape:SolidMolecular weight:346.379Cediranib Maleate
CAS:Formula:C25H27FN4O3·C4H4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:566.59Acrizanib
CAS:Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.Formula:C20H18F3N7O2Purity:98.71% - 98.72%Color and Shape:SolidMolecular weight:445.4Ref: TM-T5373
1mg111.00€5mg274.00€10mg424.00€25mg723.00€50mg1,008.00€100mg1,311.00€1mL*10mM (DMSO)303.00€Anti-VEGFR2/KDR Antibody (8D594)
Anti-VEGFR2/KDR Antibody (8D594) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (8D594) can be used in FCM.Color and Shape:Odour LiquidSU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:99.72%Color and Shape:SolidMolecular weight:442.48Pz-1
CAS:Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Formula:C26H26N6O2Purity:99.95%Color and Shape:SolidMolecular weight:454.52Cabozantinib S-malate
CAS:Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.Formula:C32H30FN3O10Purity:100% - 99.41%Color and Shape:SolidMolecular weight:635.59Linifanib
CAS:Formula:C21H18FN5OPurity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:375.41CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formula:C22H25FN4O2Purity:97.14%Color and Shape:SolidMolecular weight:396.46Regorafenib
CAS:Formula:C21H15ClF4N4O3Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:482.82Naphazoline
CAS:Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Formula:C14H14N2Purity:99.25%Color and Shape:White Crystalline Powder SolidMolecular weight:210.27SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31Tyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formula:C16H14N2O2Purity:97.51%Color and Shape:SolidMolecular weight:266.29Ref: TM-T13238
1mg52.00€5mg97.00€10mg160.00€25mg271.00€50mg416.00€100mg620.00€500mg1,283.00€1mL*10mM (DMSO)111.00€Chloropyramine hydrochloride
CAS:Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.Formula:C16H20ClN3·HClPurity:99.45% - 99.8%Color and Shape:SolidMolecular weight:326.26
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