VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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Pazopanib
CAS:Formula:C21H23N7O2SPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:437.52AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formula:C25H20F3N5O2Purity:98.9%Color and Shape:SolidMolecular weight:479.45TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurity:99.28% - 99.82%Color and Shape:SolidMolecular weight:380.85Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formula:C22H18N4OSPurity:98.9% - 99.81%Color and Shape:Off-White SolidMolecular weight:386.47VEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.Color and Shape:Odour SolidSu1498
CAS:Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.Formula:C25H30N2O2Purity:99.54%Color and Shape:SolidMolecular weight:390.52Ref: TM-T3980
1mg40.00€2mg51.00€5mg79.00€10mg119.00€25mg221.00€50mg329.00€100mg487.00€1mL*10mM (DMSO)87.00€Anti-VEGFR2/KDR Antibody-FITC (1T318)
Anti-VEGFR2/KDR Antibody-FITC (1T318) is a FITC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-FITC (1T318) can be used in FCM.Color and Shape:Odour LiquidGamabufotalin
CAS:Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.Formula:C24H34O5Purity:99.18% - 99.51%Color and Shape:SolidMolecular weight:402.52Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Formula:C22H23N5OPurity:98% - 98.87%Color and Shape:SolidMolecular weight:373.45Nintedanib
CAS:Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formula:C31H33N5O4Purity:98% - 99.92%Color and Shape:SolidMolecular weight:539.62LY2874455
CAS:LY2874455 has been used in trials studying the treatment of Advanced Cancer.Formula:C21H19Cl2N5O2Purity:97.22% - 99.46%Color and Shape:SolidMolecular weight:444.31Ref: TM-T2361
1mg52.00€5mg97.00€10mg160.00€25mg313.00€50mg494.00€100mg742.00€200mg1,008.00€1mL*10mM (DMSO)111.00€Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:464.82Ginsenoside Rk2
CAS:Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities.Formula:C36H60O7Color and Shape:SolidMolecular weight:604.869Tinengotinib
CAS:Tinengotinib is a multikinase inhibitor that targets a series of kinases , including Aurora kinases A/B, JAK1/2, FGFR1/2/3, VEGFRs, and many other kinases.Formula:C20H19ClN6OPurity:99.05%Color and Shape:SolidMolecular weight:394.86CP-547632
CAS:CP-547632 is an oral ATP-competitive inhibitor of VEGFR-2/FGF kinase with IC50s of 11/9 nM, highly selective, has antitumor activity.Formula:C20H24BrF2N5O3SPurity:98.51%Color and Shape:SolidMolecular weight:532.4Anti-VEGFR2/KDR Antibody-APC (8D594)
Anti-VEGFR2/KDR Antibody-APC (8D594) is a APC-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (8D594) can be used in FCM.Color and Shape:Odour LiquidVEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature,Color and Shape:Lyophilized PowderMolecular weight:84.37 kDa (predicted). Due to glycosylation, the protein migrates to 115-145 kDa based on Tris-Bis PAGE result.BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purity:99.08%Color and Shape:SolidMolecular weight:368.43Treprostinil Sodium
CAS:Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).Formula:C23H33NaO5Purity:99.67% - 99.95%Color and Shape:SolidMolecular weight:412.5Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56VEGFR2-IN-4
VEGFR2-IN-4 (compound 25) is a potent, selective inhibitor of the VEGFR2 kinase, exhibiting a GI50 of 0.7 nM and demonstrating anti-angiogenic effects.Formula:C23H20N4O3SPurity:98%Color and Shape:SolidMolecular weight:432.49AG-13958
CAS:AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.Formula:C26H22FN7OPurity:99.40%Color and Shape:SolidMolecular weight:467.5Ref: TM-T7493
1mg97.00€5mg264.00€10mg406.00€25mg655.00€50mg944.00€100mg1,254.00€1mL*10mM (DMSO)274.00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg50.00€10mg85.00€25mg126.00€50mg188.00€100mg274.00€200mg505.00€500mg815.00€1mL*10mM (DMSO)52.00€Anti-VEGFR2/KDR Antibody-FITC (4B612)
Anti-VEGFR2/KDR Antibody-FITC (4B612) is a FITC-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-FITC (4B612) can be used in FCM.Color and Shape:Odour LiquidCYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurity:96.6% - 97.59%Color and Shape:SolidMolecular weight:368.46Ref: TM-T6458
2mg39.00€5mg56.00€10mg78.00€25mg135.00€50mg217.00€100mg358.00€500mg908.00€1mL*10mM (DMSO)49.00€Penduletin
CAS:Penduletin: anti-inflammatory, anti-tumor, anti-bacterial, inhibits neisseria gonorrhoeae, fights EV71 with low toxicity.Formula:C18H16O7Purity:98%Color and Shape:SolidMolecular weight:344.319Anti-VEGFR2/KDR Antibody-APC (6M522)
Anti-VEGFR2/KDR Antibody-APC (6M522) is a APC-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (6M522) can be used in FCM.Color and Shape:Odour LiquidRhamnazin
CAS:Rhamnazin (3',7-Dimethylquercetin) is a VEGFR2 signaling pathway inhibitor with anti-angiogenic, anti-tumor, antioxidant, and anti-inflammatory activities.Formula:C17H14O7Purity:98%Color and Shape:SolidMolecular weight:330.29Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formula:C21H19ClN4O4Purity:98.46% - 99.8000%Color and Shape:SolidMolecular weight:426.85Faricimab
CAS:Faricimab, a bispecific antibody, simultaneously targets angiopoietin-2 and vascular endothelial growth factor-A (VEGF-A), and is utilized in research onPurity:98%Color and Shape:LiquidSorafenib tosylate
CAS:Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formula:C21H16ClF3N4O3·C7H8O3SPurity:99.2% - 99.94%Color and Shape:White To Off-White Crystalline PowderMolecular weight:637.03VEGFR-2-IN-36
VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstratedFormula:C24H23N7O5Purity:98%Color and Shape:SolidMolecular weight:489.48VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:50.4 kDa (predicted)Jaceidin
CAS:Jaceidin (Quercetagetin 3,3',6-trimethyl ether) is a membrane-permeable inhibitor of VEGFR with anti-tumor activities.Formula:C18H16O8Purity:98%Color and Shape:SolidMolecular weight:360.31Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07%Color and Shape:SolidMolecular weight:510.36Ref: TM-T8482
1mg80.00€5mg167.00€10mg281.00€25mg500.00€50mg727.00€100mg1,198.00€200mg1,596.00€1mL*10mM (DMSO)213.00€AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56TG 100572
CAS:TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2Formula:C26H26ClN5O2Purity:98%Color and Shape:SolidMolecular weight:475.97Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Ref: TM-T5164
1mg44.00€2mg55.00€5mg69.00€10mg97.00€25mg169.00€50mg248.00€100mg349.00€200mg568.00€500mg908.00€Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formula:C11H12Cl2N2O5Purity:99.6% - 99.84%Color and Shape:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidMolecular weight:323.13Regorafenib Hydrochloride
CAS:Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formula:C21H16Cl2F4N4O3Purity:99.56%Color and Shape:SolidMolecular weight:519.28hCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Formula:C24H28N6O6SPurity:98%Color and Shape:SolidMolecular weight:528.58Anti-VEGFR2/KDR Antibody-APC (4B612)
Anti-VEGFR2/KDR Antibody-APC (4B612) is a APC-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (4B612) can be used in FCM.Color and Shape:Odour LiquidAKB-6899
CAS:AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treatedFormula:C14H11FN2O4Purity:97.11%Color and Shape:SolidMolecular weight:290.25Ref: TM-T29797
1mg74.00€5mg169.00€10mg263.00€25mg455.00€50mg652.00€100mg929.00€1mL*10mM (DMSO)178.00€Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 98.03%Color and Shape:SolidMolecular weight:488.54KRN-633
CAS:KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.Formula:C20H21ClN4O4Purity:99.22% - 99.65%Color and Shape:SolidMolecular weight:416.86Ref: TM-T6137
2mg42.00€5mg64.00€10mg90.00€25mg149.00€50mg210.00€100mg313.00€200mg445.00€1mL*10mM (DMSO)70.00€SU 1498
CAS:Formula:C25H30N2O2Purity:>98.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:390.53TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Formula:C26H27Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:512.43SU 5416
CAS:Formula:C15H14N2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:238.29BIBF 1202
CAS:BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).Formula:C30H31N5O4Purity:98.04%Color and Shape:SolidMolecular weight:525.6Ref: TM-TQ0321
5mg104.00€10mg154.00€25mg298.00€50mg439.00€100mg645.00€500mg1,359.00€1mL*10mM (DMSO)115.00€
