VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51Ref: TM-T2500
2mg42.00€5mg63.00€10mg92.00€25mg136.00€50mg177.00€100mg254.00€200mg462.00€500mg742.00€1mL*10mM (DMSO)69.00€ZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formula:C22H19ClFN3O2Purity:100%Color and Shape:SolidMolecular weight:411.86Ansornitinib
CAS:Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.Formula:C30H32N6O4Color and Shape:SolidMolecular weight:540.61MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38Axitinib
CAS:Formula:C22H18N4OSPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:386.47PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFormula:C25H20Cl2N2O3Purity:99.19%Color and Shape:SolidMolecular weight:467.34Ref: TM-T12574
1mg117.00€5mg243.00€10mg369.00€25mg622.00€50mg885.00€100mg1,206.00€1mL*10mM (DMSO)250.00€BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purity:97.71% - 99.36%Color and Shape:SolidMolecular weight:439.39JK-P3
CAS:Formula:C18H17N3O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:323.35PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formula:C28H41N7O3Purity:98.15% - 98.21%Color and Shape:Yellow SolidMolecular weight:523.67Ref: TM-T2642
5mg43.00€10mg57.00€25mg89.00€50mg140.00€100mg221.00€200mg393.00€500mg655.00€1mL*10mM (DMSO)59.00€Riddelline
CAS:Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.Formula:C18H23NO6Purity:98%Color and Shape:SolidMolecular weight:349.38Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:61.5 kDa (predicted)Anti-VEGFR2/KDR Antibody (4D988)
Anti-VEGFR2/KDR Antibody (4D988) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (4D988) can be used in ELISA.Color and Shape:Odour LiquidZM 306416
CAS:ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).Formula:C16H13ClFN3O2Purity:99.31% - ≥95%Color and Shape:SolidMolecular weight:333.74Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purity:98.21% - 99.39%Color and Shape:SolidMolecular weight:246.3Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Purity:95.4% (SEC-HPLC) - CE-SDS:97.5% SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:146.53 kDaRef: TM-T9904
1mg127.00€2mg202.00€5mg376.00€10mg560.00€25mg895.00€50mg1,216.00€100mg1,634.00€200mg2,213.00€Dovitinib Dilactic Acid
CAS:Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.Formula:C21H21FN6O·2C3H6O3Purity:98%Color and Shape:SolidMolecular weight:572.59Carvedilol
CAS:Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.Formula:C24H26N2O4Purity:99.73% - 99.88%Color and Shape:Colourless Crystalline PowderMolecular weight:406.47Ref: TM-T0447
25mgTo inquire50mgTo inquire100mgTo inquire200mgTo inquire500mgTo inquire1mL*10mM (DMSO)To inquireIMPDH2-IN-4
IMPDH2-IN-4 (compound 2d) is a Mycophenolic acid analog and a selective IMPDH2 inhibitor with a Ki of 1.8 μM. It exhibits potent cytotoxic activity against osteosarcoma cancer cell lines. Additionally, IMPDH2-IN-4 demonstrates high affinity for VEGFR-2, CDK2, and IMPDH.Formula:C35H34O6SiColor and Shape:SolidMolecular weight:578.73Coumarin-3-carboxylic acid
CAS:The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/Formula:C10H6O4Purity:99.88%Color and Shape:Light Brown Crystalline PowderMolecular weight:190.15PKI-166
CAS:PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth & spread of many human cancers, including pancreatic.Formula:C20H18N4OPurity:99.76%Color and Shape:SolidMolecular weight:330.38Ref: TM-T16549
1mg42.00€5mg119.00€10mg188.00€25mg376.00€50mg628.00€100mg1,008.00€200mg1,349.00€1mL*10mM (DMSO)131.00€VEGFR-2-IN-37
CAS:VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formula:C18H16N2O2SPurity:98%Color and Shape:SolidMolecular weight:324.4Pamufetinib
CAS:Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase.Formula:C27H23FN4O4SPurity:99.39%Color and Shape:SolidMolecular weight:518.56Ref: TM-T13108
1mg50.00€5mg106.00€10mg158.00€25mg258.00€50mg379.00€100mg538.00€200mg733.00€1mL*10mM (DMSO)134.00€SYHA1815
CAS:SYHA1815, an orally active RET inhibitor (IC50=0.9 nmol/L), demonstrates antitumor activity. It exhibits greater selectivity for RET over KDR (IC50=15.9 nmol/L). SYHA1815 operates by downregulating c-Myc, arresting the G1 cell cycle, and inhibiting RET-driven cell proliferation.Formula:C27H26ClF4N5OColor and Shape:SolidMolecular weight:547.98Fruquintinib
CAS:Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39Ref: TM-T2656
2mg35.00€5mg52.00€10mg85.00€25mg117.00€50mg147.00€100mg250.00€500mg620.00€1mL*10mM (DMSO)58.00€ODM-203 sodium
ODM-203 sodium is an orally bioavailable selective and efficient FGFR and VEGFR inhibitor with antitumor activity, used in solid tumor research.Formula:C26H20F2N5NaO2SPurity:99.89%Color and Shape:SolidMolecular weight:527.52VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:84.6 kDa (predicted)JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:SolidMolecular weight:364.79Ref: TM-T22349
1mg52.00€2mg74.00€5mg105.00€10mg156.00€25mg259.00€50mg378.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)113.00€Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.Formula:C15H14N2OPurity:99.84%Color and Shape:Yellow To Yellow OrangeMolecular weight:238.28Anti-VEGFR2/KDR Antibody-APC (5U735)
Anti-VEGFR2/KDR Antibody-APC (5U735) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (5U735) can be used in FCM.Color and Shape:Odour LiquidVGX100
VGX100 is a humanized antibody targeting VEGFC for the study of solid tumors.Color and Shape:LiquidMolecular weight:145.5Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.Formula:C21H20ClFN2OSPurity:98%Color and Shape:SolidMolecular weight:402.91CP-547632 TFA
CAS:CP-547632 TFA, an oral VEGFR-2 and FGF inhibitor, IC50: VEGFR-2 at 11 nM, FGF at 9 nM, shows antitumor activity.Formula:C22H25BrF5N5O5SPurity:98%Color and Shape:SolidMolecular weight:646.43(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurity:100% - 98.13%Color and Shape:SolidMolecular weight:329.17Ref: TM-T23554
2mg35.00€5mg52.00€10mg81.00€25mg138.00€50mg215.00€100mg329.00€200mg464.00€1mL*10mM (DMSO)52.00€SU 4981
CAS:SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.Formula:C19H18N2O2Purity:100%Color and Shape:SoildMolecular weight:306.36Ref: TM-T60094
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)248.00€Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Formula:C26H21F3N4O4Purity:98.98% - 99.39%Color and Shape:SolidMolecular weight:510.46PD 173074
CAS:Formula:C28H41N7O3Purity:>95.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:523.68RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41Ref: TM-T6296
1mg47.00€2mg63.00€5mg87.00€10mg147.00€25mg266.00€50mg435.00€100mg640.00€1mL*10mM (DMSO)99.00€Ramucirumab
CAS:Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.Formula:C285H434N74O88S2Purity:99.2% (SEC-HPLC) - 99.20%Color and Shape:LiquidMolecular weight:143.77 kDaMotesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormula:C22H23N5O·2H3PO4Purity:99.76%Color and Shape:SolidMolecular weight:569.44Carvedilol phosphate hemihydrate
CAS:Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.Formula:C24H26N2O4·5H2O·H3O4PPurity:99.24%Color and Shape:SolidMolecular weight:513.49E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purity:98.83%Color and Shape:SolidMolecular weight:378.46Ref: TM-T6823
1mg50.00€2mg72.00€5mg107.00€10mg167.00€25mg304.00€50mg500.00€100mg725.00€200mg1,017.00€500mg1,510.00€1mL*10mM (DMSO)88.00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Ref: TM-T1792L
5mg35.00€10mg48.00€25mg69.00€50mg88.00€100mg140.00€200mg207.00€500mg348.00€1mL*10mM (DMSO)58.00€Anti-VEGFR2/KDR Antibody-PE (1T318)
Anti-VEGFR2/KDR Antibody-PE (1T318) is a PE-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (1T318) can be used in FCM.Color and Shape:Odour LiquidSuvemcitug
CAS:Suvemcitug, an IgG1κ antibody, specifically targets vascular endothelial growth factor (VEGF) and is derived from the African hare (Oryctolagus cuniculus) [1].Purity:98%Color and Shape:LiquidTakeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99Ref: TM-T22436
1mg97.00€2mg135.00€5mg188.00€10mg283.00€25mg462.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)255.00€Brivanib
CAS:Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormula:C19H19FN4O3Purity:98.87%Color and Shape:SolidMolecular weight:370.38Ref: TM-T6036
1mg47.00€5mg88.00€10mg144.00€25mg259.00€50mg375.00€100mg560.00€200mg815.00€1mL*10mM (DMSO)97.00€VEGFR2-IN-3
CAS:VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].Formula:C26H28ClN5O4Purity:98%Color and Shape:SolidMolecular weight:509.98Anti-VEGFR2/KDR Antibody-PE (8D594)
Anti-VEGFR2/KDR Antibody-PE (8D594) is a PE-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (8D594) can be used in FCM.Color and Shape:Odour LiquidAnti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805)
Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805) is a Rabbit antibody targeting Phospho-VEGF Receptor 2 (Tyr1175). Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805) can be used in WB.Color and Shape:Odour Liquid
