VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Formula:C18H14ClFN4OPurity:97.96%Color and Shape:SolidMolecular weight:356.78VEGFR-2-IN-33
VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achievingFormula:C20H14N6O2S2Purity:98%Color and Shape:SolidMolecular weight:434.49AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)92.00€AG 1406
CAS:AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.Formula:C16H18N2OPurity:98.12%Color and Shape:SolidMolecular weight:254.33VEGFR2/KDR Protein, Human, Recombinant (His)
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:95.9%Color and Shape:Lyophilized PowderMolecular weight:84.6 kDa (predicted); 120-130 kDa (reducing condition, due to glycosylation)Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purity:99.46% - 99.66%Color and Shape:SolidMolecular weight:441.46Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurity:98.78% - 99.72%Color and Shape:White PowderMolecular weight:437.52Ref: TM-T0097L
10mg49.00€25mg73.00€50mg96.00€100mg145.00€200mg236.00€500mg331.00€1mL*10mM (DMSO)59.00€XL 999
CAS:Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)Formula:C26H28FN5OPurity:98.24% - 99.55%Color and Shape:SolidMolecular weight:445.53Anti-VEGFR2/KDR Antibody-PE (5U735)
Anti-VEGFR2/KDR Antibody-PE (5U735) is a PE-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (5U735) can be used in FCM.Color and Shape:Odour LiquidMGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formula:C26H20FN5O2S2Purity:98.06% - 98.68%Color and Shape:SolidMolecular weight:517.6Vomifoliol
CAS:Vomifoliol, precursor to dehydrovomifoliol and anti-proliferative for lung cancer, is made from ABA metabolism.Formula:C13H20O3Purity:98%Color and Shape:SolidMolecular weight:224.3Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purity:100% - 98.01%Color and Shape:SolidMolecular weight:310.35Pazopanib Hydrochloride
CAS:Formula:C21H23N7O2S·HClPurity:>95.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:473.98Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:97.16% - 99.37%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg47.00€5mg96.00€10mg154.00€25mg283.00€50mg464.00€100mg740.00€200mg1,008.00€1mL*10mM (DMSO)96.00€VEGFR2/HDAC1-IN-1
VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC.Purity:98%Color and Shape:Odour SolidBMS-794833
CAS:BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.Formula:C23H15ClF2N4O3Purity:98% - 99.69%Color and Shape:SolidMolecular weight:468.84Ref: TM-T2419
1mg42.00€2mg52.00€5mg88.00€10mg150.00€25mg296.00€50mg537.00€100mg772.00€1mL*10mM (DMSO)95.00€Foretinib
CAS:Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.Formula:C34H34F2N4O6Purity:98.07% - 99.68%Color and Shape:SolidMolecular weight:632.65Ref: TM-T3113
2mg39.00€5mg57.00€10mg79.00€25mg133.00€50mg207.00€100mg354.00€500mg848.00€1mL*10mM (DMSO)79.00€VEGFR-2-IN-35
VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM.Formula:C25H19N3O3Purity:98%Color and Shape:SolidMolecular weight:409.44AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.Formula:C21H21FN6OPurity:99.66% - 99.78%Color and Shape:SolidMolecular weight:392.43Ref: TM-T6289
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg328.00€200mg490.00€500mg783.00€1mL*10mM (DMSO)50.00€Sunitinib
CAS:Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).Formula:C22H27FN4O2Purity:98% - 99.67%Color and Shape:Yellow SolidMolecular weight:398.47VEGFR2/KDR Protein, Human, Recombinant (hFc)
VEGFR2/KDR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:109 kDa (predicted); 150-160 kDa (reducing condition, due to glycosylation)Lucitanib
CAS:Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Formula:C26H25N3O4Purity:96.13%Color and Shape:SolidMolecular weight:443.49Ref: TM-T15185
1mg48.00€2mg63.00€5mg87.00€10mg144.00€25mg269.00€50mg487.00€100mg710.00€1mL*10mM (DMSO)96.00€(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formula:C21H28O2Purity:98.47% - 99.72%Color and Shape:SolidMolecular weight:312.45SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32T-1-MCPAB
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 µM, effectively suppresses MCF7 cell migration and has applications in cancer research [1].Purity:98%Color and Shape:Odour SolidAnti-VEGFR2/KDR Antibody-PE (6M522)
Anti-VEGFR2/KDR Antibody-PE (6M522) is a PE-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (6M522) can be used in FCM.Color and Shape:Odour LiquidXL092
CAS:XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.Formula:C29H25FN4O5Purity:98.60%Color and Shape:SolidMolecular weight:528.53Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:96.25%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg90.00€5mg187.00€10mg305.00€25mg520.00€50mg748.00€100mg1,026.00€1mL*10mM (DMSO)215.00€4SC-203
CAS:4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formula:C33H38N8O4SPurity:96.4% - 99.73%Color and Shape:SolidMolecular weight:642.77AZD4547
CAS:AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.Formula:C26H33N5O3Purity:99.37% - 99.88%Color and Shape:SolidMolecular weight:463.57Ref: TM-T1948
2mg39.00€5mg49.00€10mg63.00€25mg88.00€50mg113.00€100mg156.00€200mg219.00€500mg366.00€1mL*10mM (DMSO)55.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:98.34% - 99.62%Color and Shape:SolidMolecular weight:419.48Cediranib
CAS:Formula:C25H27FN4O3Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:450.51AAL-993
CAS:AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.Formula:C20H16F3N3OPurity:99.06%Color and Shape:SolidMolecular weight:371.36Ref: TM-T21593
1mg46.00€5mg87.00€10mg145.00€25mg274.00€50mg432.00€100mg638.00€500mg1,359.00€1mL*10mM (DMSO)97.00€SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.Formula:C17H16N2OPurity:100%Color and Shape:SolidMolecular weight:264.32SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formula:C27H24F3N5O2Purity:100% - 99.3%Color and Shape:SolidMolecular weight:507.51Ref: TM-T5194
1mg40.00€5mg84.00€10mg97.00€25mg180.00€50mg269.00€100mg430.00€500mg998.00€1mL*10mM (DMSO)87.00€Naphazoline hydrochloride
CAS:Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.Formula:C14H15ClN2Purity:97.6%Color and Shape:White Crystalline Powder White Crystalline PowderMolecular weight:246.74CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:99.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg35.00€2mg48.00€5mg74.00€10mg97.00€25mg187.00€50mg331.00€100mg547.00€1mL*10mM (DMSO)82.00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Ref: TM-T8491
1mg113.00€5mg235.00€10mg378.00€25mg630.00€50mg898.00€100mg1,216.00€1mL*10mM (DMSO)259.00€Tivozanib hydrochloride hydrate
CAS:Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formula:C22H22Cl2N4O6Purity:98.66%Color and Shape:SolidMolecular weight:509.34Taxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purity:94.91% - 98.9%Color and Shape:Yellowish PowderMolecular weight:304.25SU14813 maleate
CAS:SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formula:C27H31FN4O8Purity:98%Color and Shape:SolidMolecular weight:558.56WAY-600
CAS:WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).Formula:C28H30N8OPurity:99.63%Color and Shape:SolidMolecular weight:494.59Ref: TM-T6730
1mg38.00€2mg64.00€5mg97.00€10mg140.00€25mg245.00€50mg363.00€100mg507.00€500mgTo inquire1mL*10mM (DMSO)111.00€
