VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurity:99.43% - 99.96%Color and Shape:SolidMolecular weight:649.76Ref: TM-T5001
5mg43.00€10mg57.00€25mg71.00€50mg85.00€100mg105.00€200mg164.00€500mg316.00€1mL*10mM (DMSO)63.00€(Rac)-SAR131675
CAS:(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.Formula:C18H22N4O4Purity:98.34% - 99.1%Color and Shape:SolidMolecular weight:358.39NVP-BHG 712
CAS:Formula:C26H20F3N7OPurity:>95.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:503.49Anti-VEGFR2/KDR Antibody-APC (1T318)
Anti-VEGFR2/KDR Antibody-APC (1T318) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (1T318) can be used in FCM.Color and Shape:Odour LiquidVEGFR-2-IN-9
CAS:VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Formula:C23H25N3O3Purity:97.19%Color and Shape:SolidMolecular weight:391.46Brolucizumab
CAS:Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment exhibiting low picomolar affinity (K D = 1.05 pM), utilized for cancer research [1] [2].Purity:98%Color and Shape:LiquidMulti-kinase inhibitor 3
CAS:Multi-kinase inhibitor 3 (compound 12) is an orally active and effective multikinase (multikinase) inhibitor, demonstrating potent IC50 values against FLT1/VEGFR1, KDR/VEGFR2, FLT4/VEGFR3, FLT3, PDGFRα, and PDGFRβ, at 1.59, 1.23, 1.19, 0.59, 0.22, and 1.15 nM respectively. This compound exhibits anti-proliferative and anticancer activities.Formula:C26H26N6O2Color and Shape:SolidMolecular weight:454.52JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.35% - 99.41%Color and Shape:SolidMolecular weight:466.33Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:98.44% - 99.54%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg51.00€10mg79.00€25mg129.00€50mg213.00€100mg358.00€200mg535.00€500mg843.00€1mL*10mM (DMSO)57.00€Tanshinone IIA
CAS:Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.Formula:C19H18O3Purity:100% - 99.36%Color and Shape:Cherry CrystalMolecular weight:294.34Anti-VEGFR2/KDR Antibody (4B612)
Anti-VEGFR2/KDR Antibody (4B612) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (4B612) can be used in ELISA(Cap),FCM.Color and Shape:Odour LiquidIcrucumab
CAS:Icrucumab, a humanized antibody, inhibits VEGFR-1 and shows antitumor effects, tested in metastatic colon cancer.Purity:> 95%Color and Shape:LiquidMolecular weight:150 kDaDMH4
CAS:DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Formula:C24H24N4O2Purity:98.68%Color and Shape:SolidMolecular weight:400.47(Z)-Semaxinib
CAS:(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition forFormula:C15H14N2OPurity:96.09% - ≥95%Color and Shape:SolidMolecular weight:238.28Ref: TM-T2496
1mg57.00€5mg111.00€10mg188.00€25mg331.00€50mg568.00€100mg695.00€200mg948.00€1mL*10mM (DMSO)144.00€Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Formula:C15H10O6Purity:98% - 98%Color and Shape:SolidMolecular weight:286.24VEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formula:C20H21N7O2SPurity:99.01%Color and Shape:SolidMolecular weight:423.49N-Desethylsunitinib hydrochloride
CAS:N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Formula:C20H24ClFN4O2Purity:99.42%Color and Shape:SolidMolecular weight:406.88Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formula:C28H24FN3O5Purity:99.59% - 99.88%Color and Shape:SolidMolecular weight:501.51
