TAM Receptor
TAM receptor inhibitors target the TAM family of receptor tyrosine kinases, which includes Tyro3, Axl, and Mer. These receptors are involved in the regulation of immune responses, cell survival, and clearance of apoptotic cells. Dysregulation of TAM receptors is implicated in cancer, autoimmune diseases, and chronic inflammation. At CymitQuimica, we offer TAM receptor inhibitors to aid your research in immunology, oncology, and inflammation.
Products of "TAM Receptor"
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DS-1205
CAS:DS-1205: AXL kinase inhibitor (IC50=1.3 nM), also targets MER, MET, TRKA (IC50s: 63, 104, 407 nM), hinders cell migration and tumor growth.Formula:C41H42FN5O7Purity:99.28%Color and Shape:SolidMolecular weight:735.8TAM-IN-2
CAS:TAM-IN-2 is an inhibitor of TAM.Formula:C31H27F2N7O3Purity:98.09% - 99.74%Color and Shape:SolidMolecular weight:583.59UNC2541
CAS:UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.Formula:C24H34FN7O2Purity:98.33%Color and Shape:SolidMolecular weight:471.57UNC569
CAS:UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.Formula:C22H29FN6Purity:98.91%Color and Shape:SolidMolecular weight:396.5Ref: TM-T21302
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg311.00€50mg512.00€100mg730.00€1mL*10mM (DMSO)96.00€Ningetinib
CAS:Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C31H29FN4O5Purity:99.77% - 99.95%Color and Shape:SolidMolecular weight:556.58Bemcentinib
CAS:Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.Formula:C30H34N8Purity:97% - 99.8%Color and Shape:SolidMolecular weight:506.64Ref: TM-T6269
1mg40.00€2mg52.00€5mg87.00€10mg144.00€25mg212.00€50mg274.00€100mg465.00€200mg622.00€500mg948.00€RU-302
CAS:RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.Formula:C24H24F3N3O2SPurity:99.45%Color and Shape:SolidMolecular weight:475.53Ref: TM-T16806
1mg43.00€5mg96.00€10mg150.00€25mg259.00€50mg374.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)96.00€AXL-IN-15
CAS:AXL-IN-15 (cpd391) is a potent inhibitor of Axl, exhibiting both a dissociation constant (K i) and a half-maximal inhibitory concentration (IC50) of less than 1Formula:C26H32F3N9O3Purity:98%Color and Shape:SolidMolecular weight:575.59MerTK/Axl-IN-1
CAS:MerTK/Axl-IN-1 (Compound A-910) is a potent and selective dual inhibitor of MerTK/Axl, exhibiting IC50 values of 4.2 nM and 8.8 nM in Ba/F3 cells, and 0.2 nM and 0.9 nM in HTRF cells, respectively. It effectively inhibits pMerTK in vivo and possesses a long half-life and high oral bioavailability.Formula:C40H47FN6O4Color and Shape:SolidMolecular weight:694.84BMS 777607
CAS:BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.Formula:C25H19ClF2N4O4Purity:100% - 99.89%Color and Shape:SolidMolecular weight:512.89Ref: TM-T2699
1mg35.00€5mg79.00€10mg124.00€25mg217.00€50mg359.00€100mg533.00€500mg1,169.00€1mL*10mM (DMSO)92.00€UNC 569 hydrochloride
UNC 569 hydrochloride: reversible ATP-competitive Mer inhibitor, IC50 2.9 nM, Ki 4.3 nM, also inhibits Axl/Tyro3; used in leukemia, teratoid tumor studies.Formula:C22H30ClFN6Purity:100%Color and Shape:SolidMolecular weight:432.96SGI-7079
CAS:SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.Formula:C26H26FN7Purity:95.05% - 99.26%Color and Shape:SolidMolecular weight:455.53Ref: TM-T6982
2mg42.00€5mg62.00€10mg97.00€25mg188.00€50mg243.00€100mg354.00€500mg825.00€1mL*10mM (DMSO)67.00€XL092
CAS:XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.Formula:C29H25FN4O5Purity:98.60%Color and Shape:SolidMolecular weight:528.53LDC1267
CAS:LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).Formula:C30H26F2N4O5Purity:99.38% - 99.76%Color and Shape:SolidMolecular weight:560.55Ref: TM-T2311
1mg35.00€2mg52.00€5mg77.00€10mg105.00€25mg168.00€50mg248.00€100mg419.00€1mL*10mM (DMSO)93.00€Dubermatinib
CAS:Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.Formula:C24H30ClN7O2SPurity:98.65% - 98.92%Color and Shape:SolidMolecular weight:516.06Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79AXL-IN-14
CAS:AXL-IN-14: orally active, potent AXL inhibitor (IC50=0.8 nM); hinders Gas6/AXL migration, invasion; lowers p-AXL, p-AKT; anti-tumor.Formula:C32H24F2N4O4Purity:98%Color and Shape:SolidMolecular weight:566.55MerTK-IN-1
CAS:MerTK-IN-1 (compound 31) serves as an inhibitor of MerTK, with the capability to bind to the target in vivo.Formula:C23H26N8O4Color and Shape:SolidMolecular weight:478.50Sitravatinib malate
CAS:Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5Formula:C37H35F2N5O9SPurity:98%Color and Shape:SolidMolecular weight:763.76UNC2881
CAS:UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.Formula:C25H33N7O2Purity:98.97% - 99.74%Color and Shape:SolidMolecular weight:463.58
