FLT
FLT (Fms-like tyrosine kinase) inhibitors are compounds that target FLT receptors, which are involved in the regulation of angiogenesis through the VEGF (vascular endothelial growth factor) pathway. FLT receptors play a crucial role in the development of new blood vessels in tumors. Inhibiting FLT receptors can effectively reduce angiogenesis and tumor growth, making these inhibitors important in cancer therapy. At CymitQuimica, we offer a selection of high-quality FLT inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "FLT"
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FLT3-IN-2
CAS:FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Formula:C21H16ClF3N4Purity:97.57% - 98.53%Color and Shape:SolidMolecular weight:416.83Ref: TM-T1938
1mg43.00€2mg56.00€5mg87.00€10mg119.00€25mg210.00€50mg350.00€100mg505.00€1mL*10mM (DMSO)87.00€5'-Fluoroindirubinoxime
CAS:5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Formula:C16H10FN3O2Purity:100%Color and Shape:SolidMolecular weight:295.27UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.Formula:C28H42Cl2N6OPurity:99.71%Color and Shape:SolidMolecular weight:549.62Gilteritinib hemifumarate
CAS:Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment ofFormula:C29H44N8O3C4H4O4Purity:98.07%Color and Shape:SolidMolecular weight:610.75Dapolsertib
CAS:Dapolsertib (SEL24-B489) is an orally active and efficient PIM and FLT3-ITD inhibitor, reducing PIM-specific substrate phosphorylation.Formula:C15H18Br2N4O2Purity:99.61%Color and Shape:SolidMolecular weight:446.14FLT3-IN-3
CAS:FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.Formula:C27H38N8OPurity:99.25%Color and Shape:SolidMolecular weight:490.64Ref: TM-T11298
1mg107.00€5mg259.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€500mg2,717.00€1mL*10mM (DMSO)278.00€SB1317 hydrochloride (1204918-72-8(free base))
SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).Formula:C23H25ClN4OPurity:99.84%Color and Shape:SolidMolecular weight:408.92Ref: TM-T4227
1mg49.00€2mg69.00€5mg113.00€10mg180.00€25mg324.00€50mg393.00€100mg585.00€1mL*10mM (DMSO)124.00€BPR1J-097 hydrochloride (1327167-19-0(free base))
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.Formula:C27H29ClN6O3SPurity:98% - 98.54%Color and Shape:SolidMolecular weight:553.07UNC2541
CAS:UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.Formula:C24H34FN7O2Purity:98.33%Color and Shape:SolidMolecular weight:471.57HM43239
CAS:HM43239: oral FLT3 inhibitor; IC50: FLT3 WT 1.1nM, ITD 1.8nM, D835Y 1.0nM; blocks p-STAT5/p-ERK; affects SYK, JAK1/2, TAK1; halts leukemia cell growth.Formula:C29H33ClN6Purity:98.56%Color and Shape:SolidMolecular weight:501.07TG-46
CAS:TG-46 (TG46) inhibits JAK2, FLT3, RET, JAK3 and can be used to study glaucoma.Formula:C26H34N6O3SPurity:100% - 99.87%Color and Shape:SolidMolecular weight:510.65BPR1K871
CAS:BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFormula:C25H28ClN7O2SColor and Shape:SolidMolecular weight:526.05AXL-IN-13
CAS:AXL-IN-13: potent, oral AXL inhibitor, IC50=1.6nM, Kd=0.26nM, anti-cancer, inhibits EMT, cell migration & invasion.Formula:C34H41FN6O5Purity:99.38%Color and Shape:SolidMolecular weight:632.72Gilteritinib
CAS:Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Formula:C29H44N8O3Purity:97.75% - 99.74%Color and Shape:SolidMolecular weight:552.71Ref: TM-T4409
1g1,359.00€1mg40.00€2mg55.00€5mg89.00€10mg120.00€25mg187.00€50mg276.00€100mg434.00€500mg1,008.00€TAS05567
CAS:TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM).Formula:C21H29N9O2Purity:98%Color and Shape:SolidMolecular weight:439.51Anti-FLT1 Antibody (6S618)
Anti-FLT1 Antibody (6S618) is an antibody targeting FLT1. Anti-FLT1 Antibody (6S618) can be used in ELISA, IHC.Color and Shape:Odour LiquidTCS 359
CAS:TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.Formula:C18H20N2O4SPurity:99.31%Color and Shape:SolidMolecular weight:360.43HPK1-IN-2
CAS:HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.Formula:C19H20N6OSPurity:97.31%Color and Shape:SolidMolecular weight:380.47Ref: TM-T9017
1mg78.00€5mg143.00€10mg230.00€25mg385.00€50mg548.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)170.00€Flonoltinib
CAS:Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.Formula:C25H34FN7OPurity:99.52%Color and Shape:SolidMolecular weight:467.58FLT3-ITD-IN-2
FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.Formula:C39H50N8O6Color and Shape:SolidMolecular weight:726.86NVP-AEW541
CAS:NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormula:C27H29N5OPurity:96.03% - 99.55%Color and Shape:SolidMolecular weight:439.55VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.UNC2025
CAS:UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor.Formula:C28H40N6OPurity:99.53% - 99.74%Color and Shape:SolidMolecular weight:476.66TG-89
CAS:TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian andFormula:C26H34N6O3SPurity:98.8%Color and Shape:SolidMolecular weight:510.65FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Color and Shape:Lyophilized PowderMolecular weight:85.45 kDa (predicted); 113.32 kDa (reducing conditions)SGI-7079
CAS:SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.Formula:C26H26FN7Purity:95.05% - 99.26%Color and Shape:SolidMolecular weight:455.53Ref: TM-T6982
2mg42.00€5mg62.00€10mg97.00€25mg188.00€50mg243.00€100mg354.00€500mg825.00€1mL*10mM (DMSO)67.00€4SC-203
CAS:4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formula:C33H38N8O4SPurity:96.4% - 99.73%Color and Shape:SolidMolecular weight:642.77Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purity:97.45% - 99.28%Color and Shape:SolidMolecular weight:443.54FLT3-IN-4
CAS:FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenousFormula:C23H25N7O2Purity:98.96%Color and Shape:SolidMolecular weight:431.49Ref: TM-T11299
1mg93.00€5mg226.00€10mg335.00€25mg538.00€50mg730.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)249.00€Crotonoside
CAS:Crotonoside (Isoguanosine) is a natural product, which inhibits FLT3 and HDAC3/6 and has research potential for the treatment of acute myeloid leukaemia (AML).Formula:C10H13N5O5Purity:100% - 99.51%Color and Shape:SolidMolecular weight:283.24Ref: TM-T6S0033
5mg35.00€10mg51.00€25mg95.00€50mg131.00€100mg200.00€200mg281.00€1mL*10mM (DMSO)35.00€FLT3-IN-10
CAS:FLT3-IN-10, a potent FLT3 inhibitor, may treat FLT3-mutated AML.Formula:C15H11FN2OPurity:99.60%Color and Shape:SolidMolecular weight:254.26Ref: TM-T9856
1mg38.00€5mg85.00€10mg131.00€25mg259.00€50mg383.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)81.00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.88%Color and Shape:SolidMolecular weight:456.37Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58Anti-FLT1 Antibody (6K171)
Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF.Color and Shape:Odour LiquidAnti-FLT1 Antibody (3W705)
Anti-FLT1 Antibody (3W705) is an antibody targeting FLT1. Anti-FLT1 Antibody (3W705) can be used in ELISA, WB, IHC, FCM.Color and Shape:Odour LiquidJI6
CAS:JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.Formula:C19H17N3O4SPurity:97.74%Color and Shape:SoildMolecular weight:383.42AC710
CAS:AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).Formula:C31H42N6O4Purity:99.48%Color and Shape:SolidMolecular weight:562.7Anti-VEGFR1/FLT-1 Antibody (9F18)
Anti-VEGFR1/FLT-1 Antibody (9F18) is a Rabbit antibody targeting VEGFR1/FLT-1. Anti-VEGFR1/FLT-1 Antibody (9F18) can be used in ELISA.Color and Shape:Odour LiquidBPR1J-097
CAS:BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).Formula:C27H28N6O3SPurity:99.3%Color and Shape:SolidMolecular weight:516.61Merestinib dihydrochloride
CAS:Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formula:C30H24Cl2F2N6O3Color and Shape:SolidMolecular weight:625.45JTV-519 free base
CAS:JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmicFormula:C25H32N2O2SPurity:98%Color and Shape:SolidMolecular weight:424.6MRX-2843
CAS:MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).Formula:C29H40N6OPurity:99.63%Color and Shape:SolidMolecular weight:488.67Ref: TM-T16144
1mg65.00€5mg144.00€10mg227.00€25mg454.00€50mg655.00€100mg933.00€1mL*10mM (DMSO)157.00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurity:96.13% - 98.95%Color and Shape:SolidMolecular weight:624.42Ref: TM-T2605
1mg47.00€2mg55.00€5mg88.00€10mg124.00€25mg221.00€50mg374.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)116.00€3-Hydroxy Midostaurin
CAS:3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM inFormula:C35H30N4O5Purity:98%Color and Shape:SolidMolecular weight:586.648OTS447
CAS:OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .Formula:C27H32ClN3O2Purity:97.72%Color and Shape:SolidMolecular weight:466.027BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.Formula:C16H10BrN3O2Purity:99.77%Color and Shape:SolidMolecular weight:356.17Ref: TM-T22012
5mg46.00€10mg64.00€25mg116.00€50mg178.00€100mg284.00€200mg401.00€1mL*10mM (DMSO)52.00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formula:C23H26FN6O9PPurity:93.08% - 99.38%Color and Shape:SolidMolecular weight:580.46Ref: TM-T6115
1mg43.00€2mg57.00€5mg88.00€10mg118.00€25mg210.00€50mg335.00€100mg548.00€500mg1,198.00€1mL*10mM (DMSO)101.00€FN-1501
CAS:FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).Formula:C22H25N9OPurity:96.35%Color and Shape:SolidMolecular weight:431.49Ref: TM-T15335
1mg92.00€5mg187.00€10mg311.00€25mg567.00€50mg852.00€100mg1,159.00€1mL*10mM (DMSO)215.00€JAK3-IN-14
CAS:JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.Formula:C18H13N3OPurity:98.98%Color and Shape:SoildMolecular weight:287.32Ref: TM-T67754
1mg215.00€5mg620.00€10mg904.00€25mg1,320.00€50mg1,786.00€100mg2,432.00€1mL*10mM (DMSO)540.00€FLT1 Protein, Human, Recombinant (aa 1-756, His)
FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:83.7 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)
