Src
Src inhibitors are compounds that target Src family kinases, which are involved in various cellular processes, including growth, differentiation, and angiogenesis. Src kinases play a critical role in the signaling pathways that promote the formation of new blood vessels in tumors. Inhibiting Src can disrupt these pathways, thereby reducing angiogenesis and tumor growth. Src inhibitors are widely used in cancer research and therapeutic development. At CymitQuimica, we provide a comprehensive selection of high-quality Src inhibitors to support your research in oncology, cell signaling, and angiogenesis.
Products of "Src"
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Scutellarein
CAS:Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.Formula:C15H10O6Purity:98.02% - 99.63%Color and Shape:SolidMolecular weight:286.24A 419259
CAS:A 419259 is a pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family (IC50s: 9 nM, <3 nM and <3 nM for Src, Lck and Lyn).Formula:C29H34N6OColor and Shape:SolidMolecular weight:482.62AZ12672857
CAS:AZ12672857 is an inhibitor of EphB4 with IC50 of 1.3 nM.Formula:C26H30N8O2Purity:98.05%Color and Shape:SolidMolecular weight:486.57Ref: TM-T9650
1mg70.00€2mg93.00€5mg155.00€10mg259.00€25mg424.00€50mg662.00€100mg894.00€1mL*10mM (DMSO)166.00€UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68SU6656
CAS:SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.Formula:C19H21N3O3SPurity:97% - 98.21%Color and Shape:SolidMolecular weight:371.45Ref: TM-T6997
1mg40.00€2mg51.00€5mg85.00€10mg139.00€25mg269.00€50mg449.00€100mg667.00€1mL*10mM (DMSO)88.00€lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formula:C14H13NO5Purity:97.77%Color and Shape:Yellow To Tan PowderMolecular weight:275.26Ref: TM-T4185
1mg44.00€2mg58.00€5mg87.00€10mg160.00€25mg349.00€50mg518.00€100mg747.00€1mL*10mM (DMSO)95.00€Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFormula:C25H28O6Purity:99.94% - ≥98%Color and Shape:SolidMolecular weight:424.49PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurity:99.23%Color and Shape:SolidMolecular weight:532.51Ref: TM-T23127
1mg35.00€5mg92.00€10mg149.00€25mg305.00€50mg492.00€100mg700.00€200mg938.00€1mL*10mM (DMSO)125.00€CH6953755
CAS:CH6953755: oral YES1 kinase inhibitor, IC50 1.8 nM, potent, selective, anticancer, halts cell proliferation.Formula:C26H22F2N6O4SPurity:98.03%Color and Shape:SolidMolecular weight:552.55Ref: TM-T10784
1mg58.00€5mg123.00€10mg187.00€25mg366.00€50mg588.00€100mg944.00€1mL*10mM (DMSO)149.00€CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formula:C20H20FN7O2Purity:99.29%Color and Shape:SolidMolecular weight:409.42Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62Ref: TM-T6311
1mg37.00€2mg52.00€5mg79.00€10mg103.00€25mg159.00€50mg188.00€100mg350.00€200mg455.00€1mL*10mM (DMSO)90.00€TGF-βRI inhibitor 3
CAS:TGF-βRI inhibitor 3 (Compound 9ac) is a selective inhibitor of TGF-β that effectively suppresses the TGF-β signaling pathway. It exhibits IC50 values of 13 μM for c-Src kinase and 0.63 μM for ALK5 kinase.Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.396PP 3
CAS:PP 3 is a Negative control for the Src kinase inhibitor PP 2Formula:C11H9N5Purity:98.61%Color and Shape:Whit To Off-White SolidMolecular weight:211.22Ref: TM-T23176
5mg51.00€10mg79.00€25mg140.00€50mg202.00€100mg305.00€500mg733.00€1mL*10mM (DMSO)55.00€Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purity:98.98% - 99.9%Color and Shape:Yellowish-Orange Or Pink To Brownish Solid Solid PowderMolecular weight:530.45OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.391-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formula:C19H19N5Purity:99.85%Color and Shape:White Cyrstalline SolidMolecular weight:317.39PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:98.34% - 99.62%Color and Shape:SolidMolecular weight:419.48BT424
CAS:BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].Formula:C22H15BCl2N2O2Purity:98%Color and Shape:SolidMolecular weight:421.08WHI-P154
CAS:Formula:C16H14BrN3O3Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:376.21Tolimidone
CAS:Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.Formula:C11H10N2O2Purity:99.85% - 99.85%Color and Shape:SolidMolecular weight:202.21TL02-59 dihydrochloride
CAS:TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).Formula:C32H36Cl2F3N5O4Purity:98%Color and Shape:SolidMolecular weight:682.56A-770041
CAS:A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Formula:C34H39N9O3Purity:99.23% - 99.86%Color and Shape:SolidMolecular weight:621.73Ref: TM-T14074
1mg55.00€5mg116.00€10mg188.00€25mg426.00€50mg725.00€100mg1,130.00€200mg1,501.00€1mL*10mM (DMSO)159.00€A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurity:100% - 99.47%Color and Shape:SolidMolecular weight:592Ref: TM-TQ0132
1mg52.00€2mg74.00€5mg107.00€10mg170.00€25mg319.00€50mg557.00€100mg797.00€500mg1,586.00€GluR6 antagonist-1
CAS:GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formula:C15H11ClN2OSPurity:98.07%Color and Shape:SolidMolecular weight:302.78Ref: TM-T9723
2mg38.00€5mg58.00€10mg90.00€25mg138.00€50mg197.00€100mg294.00€200mg411.00€1mL*10mM (DMSO)65.00€KX1-004
CAS:KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.Formula:C16H13FN2O2Purity:99.12% - ≥95%Color and Shape:SolidMolecular weight:284.29Ref: TM-T1812
1mg46.00€2mg59.00€5mg87.00€10mg160.00€25mg283.00€50mg465.00€100mg655.00€500mg1,378.00€1mL*10mM (DMSO)97.00€Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurity:100% - 99.68%Color and Shape:SolidMolecular weight:506.03Src Inhibitor 1
CAS:Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.Formula:C22H19N3O3Purity:100% - 99.38%Color and Shape:SolidMolecular weight:373.4MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formula:C20H20N2OPurity:98.17% - 99.33%Color and Shape:SolidMolecular weight:304.39Ref: TM-T6886
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg259.00€50mg378.00€100mg567.00€1mL*10mM (DMSO)96.00€1-Naphthyl PP1 hydrochloride
CAS:1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormula:C19H20ClN5Purity:98.63%Color and Shape:SolidMolecular weight:353.85NVP-BHG 712
CAS:Formula:C26H20F3N7OPurity:>95.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:503.49SI-2 hydrochloride
CAS:SI-2 hydrochloride, an SRC-3 inhibitor, induces breast cancer cell death (IC50: 3-20 nM) with good oral bioavailability.Formula:C15H16ClN5Purity:98.18%Color and Shape:SolidMolecular weight:301.771-NM-PP1
CAS:1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.Formula:C20H21N5Purity:98% - 98.93%Color and Shape:White Cyrstalline SolidMolecular weight:331.41Ref: TM-T2153
1mg50.00€2mg66.00€5mg88.00€10mg139.00€25mg286.00€50mg532.00€100mg705.00€1mL*10mM (DMSO)95.00€Rebastinib
CAS:DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,Formula:C30H28FN7O3Purity:99.53% - 99.79%Color and Shape:SolidMolecular weight:553.59PP 2
CAS:Formula:C15H16ClN5Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:301.78AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurity:99.94%Color and Shape:SolidMolecular weight:217.65Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormula:C31H32N8O5Purity:98%Color and Shape:SolidMolecular weight:596.64PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:95.65% - 98%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg47.00€5mg69.00€10mg116.00€25mg188.00€50mg321.00€100mg510.00€200mg725.00€1mL*10mM (DMSO)74.00€PP 1
CAS:Formula:C16H19N5Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:281.36Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01TL02-59
CAS:TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Formula:C32H34F3N5O4Purity:95.63%Color and Shape:SolidMolecular weight:609.64Ref: TM-T13186
1mg71.00€5mg135.00€10mg212.00€25mg359.00€50mg512.00€100mg695.00€200mg937.00€1mL*10mM (DMSO)170.00€Bosutinib
CAS:Formula:C26H29Cl2N5O3Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:530.45Dasatinib
CAS:Formula:C22H26ClN7O2SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:488.01PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormula:C21H16Cl2N4OSPurity:98.52% - 99.28%Color and Shape:SolidMolecular weight:443.35RK-24466
CAS:RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.Formula:C23H22N4OPurity:98.07%Color and Shape:SolidMolecular weight:370.45Ref: TM-T16760
1mg66.00€5mg144.00€10mg227.00€25mg393.00€50mg588.00€100mg905.00€1mL*10mM (DMSO)159.00€Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99.42%Color and Shape:SolidMolecular weight:527.63Ref: TM-T15675
2mg38.00€5mg56.00€10mg70.00€25mg126.00€50mg243.00€100mg416.00€200mg562.00€1mL*10mM (DMSO)65.00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:100% - 99.55%Color and Shape:SolidMolecular weight:498.64Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56
