c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
Products of "c-Kit"
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c-Kit Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:99.4%Color and Shape:Lyophilized PowderMolecular weight:56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formula:C20H16ClN5O3Purity:97.61% - 99.81%Color and Shape:SolidMolecular weight:409.83JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:SolidMolecular weight:364.79Ref: TM-T22349
1mg52.00€2mg74.00€5mg105.00€10mg156.00€25mg259.00€50mg378.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)113.00€M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formula:C29H32N8OPurity:98.52%Color and Shape:SolidMolecular weight:508.62Ref: TM-T9689
1mg52.00€5mg116.00€10mg178.00€25mg306.00€50mg437.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)129.00€Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormula:C22H23N5O·2H3PO4Purity:99.76%Color and Shape:SolidMolecular weight:569.44Anti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Color and Shape:Odour LiquidPLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formula:C21H17F3N4Purity:99.38%Color and Shape:SolidMolecular weight:382.38Ref: TM-T1925
2mg42.00€5mg60.00€10mg90.00€25mg134.00€50mg188.00€100mg279.00€200mg411.00€1mL*10mM (DMSO)64.00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)92.00€Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurity:98.78% - 99.72%Color and Shape:White PowderMolecular weight:437.52Ref: TM-T0097L
10mg49.00€25mg73.00€50mg96.00€100mg145.00€200mg236.00€500mg331.00€1mL*10mM (DMSO)59.00€Anti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidBLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formula:C27H29FN10OPurity:99.67%Color and Shape:SolidMolecular weight:528.58Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:97.16% - 99.37%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg47.00€5mg96.00€10mg154.00€25mg283.00€50mg464.00€100mg740.00€200mg1,008.00€1mL*10mM (DMSO)96.00€Anti-C-Kit Antibody (3F840)
Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.Color and Shape:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Color and Shape:Odour Liquidc-Kit Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Purity:97.1%Color and Shape:Lyophilized PowderMolecular weight:82 kDa (predicted); 93-115 kDa (reducing conditions)Anti-C-Kit Antibody (3N57)
Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).Color and Shape:Odour LiquidBezuclastinib
CAS:Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.Formula:C19H17N5OPurity:99.81%Color and Shape:SolidMolecular weight:331.37AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.Formula:C21H21FN6OPurity:99.66% - 99.78%Color and Shape:SolidMolecular weight:392.43Ref: TM-T6289
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg328.00€200mg490.00€500mg783.00€1mL*10mM (DMSO)50.00€KG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).Formula:C20H16F3N7OSPurity:98.2%Color and Shape:SolidMolecular weight:459.45Ref: TM-T41003
1mg34.00€2mg47.00€5mg74.00€10mg105.00€25mg205.00€50mg313.00€100mg449.00€200mg628.00€1mL*10mM (DMSO)89.00€Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purity:98.34% - 99.51%Color and Shape:SolidMolecular weight:417.81Ref: TM-T2115
5mg48.00€10mg62.00€25mg95.00€50mg120.00€100mg154.00€200mg202.00€500mg350.00€1mL*10mM (DMSO)52.00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:96.25%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg90.00€5mg187.00€10mg305.00€25mg520.00€50mg748.00€100mg1,026.00€1mL*10mM (DMSO)215.00€Anti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Color and Shape:Odour LiquidMulti-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formula:C20H17F3N4O3Purity:99.34%Color and Shape:SolidMolecular weight:418.37CHMFL-ABL/KIT-155
CAS:CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).Formula:C33H38F3N5O3Purity:98%Color and Shape:SolidMolecular weight:609.68CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Color and Shape:Lyophilized PowderMolecular weight:56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:98.2%Color and Shape:Lyophilized PowderMolecular weight:57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Color and Shape:Odour LiquidDovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Formula:C19H21N3O2SPurity:98.39%Color and Shape:SolidMolecular weight:355.45c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.Formula:C25H28FN5O5Color and Shape:SolidMolecular weight:497.52Anti-C-Kit Antibody (1R766)
Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.Color and Shape:Odour LiquidImatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurity:100% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Ref: TM-T2624
1mg51.00€5mg93.00€10mg144.00€25mg263.00€50mg424.00€100mg612.00€200mg873.00€1mL*10mM (DMSO)97.00€
