Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Isorhapontigenin
CAS:Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.Formula:C15H14O4Purity:98.49% - 99.85%Color and Shape:Off White Crystals PowerMolecular weight:258.27KB-R7943 mesylate
CAS:KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.Formula:C17H21N3O6S2Purity:99.22% - ≥95%Color and Shape:SolidMolecular weight:427.5Nilotinib
CAS:Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.Formula:C28H22F3N7OPurity:99.61% - 99.83%Color and Shape:Off-White SolidMolecular weight:529.52Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.36Ixazomib citrate
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).Formula:C20H23BCl2N2O9Purity:100% - 98.37%Color and Shape:SolidMolecular weight:517.12Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purity:99.46% - 99.66%Color and Shape:SolidMolecular weight:441.46E-64
CAS:E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.Formula:C15H27N5O5Purity:98% - 99.95%Color and Shape:White SolidMolecular weight:357.41Ref: TM-T6037
2mg37.00€5mg50.00€10mg79.00€25mg140.00€50mg225.00€100mg335.00€500mg790.00€1mL*10mM (DMSO)51.00€Fluoxetine hydrochloride
CAS:Fluoxetine HCl (Lilly110140), a selective serotonin reuptake inhibitor (SSRI), is an antidepressant with fewer side effects.Formula:C17H19ClF3NOPurity:99.6% - 99.98%Color and Shape:White To Off-White Crystalline Solid White To Off-White PowderMolecular weight:345.787Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurity:98.78% - 99.72%Color and Shape:White PowderMolecular weight:437.52Ref: TM-T0097L
10mg49.00€25mg73.00€50mg96.00€100mg145.00€200mg236.00€500mg331.00€1mL*10mM (DMSO)59.00€Lasalocid sodium
CAS:Lasalocid sodium, an antibiotic from Streptomyces lasaliensis, regulates calcium in muscles and is used as a poultry coccidiostat.Formula:C34H53NaO8Purity:97.08% - 98.49%Color and Shape:SolidMolecular weight:612.77Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.Formula:C29H25F4N3O5SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:603.58Ref: TM-T4379
1mg87.00€5mg166.00€10mg248.00€25mg437.00€50mg665.00€100mg1,008.00€200mg1,520.00€500mg2,252.00€1mL*10mM (DMSO)213.00€Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formula:C10H16ClN5Purity:97.11% - 99.23%Color and Shape:Lactic AcidosisMolecular weight:241.72BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76Torkinib
CAS:Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).Formula:C16H16N6OPurity:99.11%Color and Shape:SolidMolecular weight:308.34Ref: TM-T2414
5mg57.00€10mg74.00€25mg96.00€50mg136.00€100mg227.00€200mg338.00€500mg560.00€1mL*10mM (DMSO)63.00€Iohexol
CAS:Iohexol, a contrast agent, has an osmolality of 322-844 mOsm/kg, 1.1-3 times blood plasma's.Formula:C19H26I3N3O9Purity:80.18% - 99.61%Color and Shape:White To Off-White Solid PowderMolecular weight:821.14Soyasapogenol B
CAS:Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.Formula:C30H50O3Purity:99.81% - 99.92%Color and Shape:SolidMolecular weight:458.72PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurity:97.21% - 98.59%Color and Shape:SolidMolecular weight:347.39Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purity:99.19% - 99.68%Color and Shape:SolidMolecular weight:432.46Honokiol
CAS:Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.Formula:C18H18O2Purity:99.65% - 99.94%Color and Shape:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TasteMolecular weight:266.33Calcimycin
CAS:Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.Formula:C29H37N3O6Purity:98%Color and Shape:SolidMolecular weight:523.62Autophagy-lysosome activator-1
Autophagy-lysosome Activator-1 (Compound F1) is an autophagy-lysosome stimulator that effectively induces the degradation of PD-L1 or VISTA in tumor cells.Formula:C17H18N4O2Color and Shape:SolidMolecular weight:310.35Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5SPurity:98.85% - 99.58%Color and Shape:SolidMolecular weight:556.76
