Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purity:99.79% - 99.95%Color and Shape:SolidMolecular weight:408.45ML-SA5
CAS:ML-SA5 is a MCOLN1 agonist that blocks autophagic flux by disrupting fusion between autophagosomes and lysosomes.Cost-effective and quality-assured.Formula:C19H24ClN3O4S2Purity:100.00% - 99.16%Color and Shape:SoildMolecular weight:457.99IU1
CAS:IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂,可以穿透细胞,IC50为 4.7 μM。Formula:C18H21FN2OPurity:98% - 99.30%Color and Shape:SolidMolecular weight:300.37Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formula:C50H46CaF2N2O8Purity:100% - 99.49%Color and Shape:White To Off-White PowderMolecular weight:880.98Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H19N5Purity:98% - 99.77%Color and Shape:SolidMolecular weight:329.4Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formula:C22H19N5O2Purity:≥95%Color and Shape:SolidMolecular weight:385.42Tazarotene
CAS:Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formula:C21H21NO2SPurity:97.01% - 99.14%Color and Shape:White SolidMolecular weight:351.46Ref: TM-T6696
5mg38.00€10mg49.00€25mg88.00€50mg147.00€100mg256.00€200mg334.00€500mg563.00€1mL*10mM (DMSO)55.00€BI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formula:C19H23F2N5O2Purity:98.51% - 99.43%Color and Shape:SolidMolecular weight:391.42Ref: TM-T6171
1mg52.00€2mg78.00€5mg137.00€10mg207.00€25mg335.00€50mg472.00€100mg658.00€500mg1,378.00€1mL*10mM (DMSO)117.00€Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formula:C23H34O5Purity:99.12%Color and Shape:White-Yellowish To Yellow Powder Solid PowderMolecular weight:390.51Tezacaftor
CAS:Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formula:C26H27F3N2O6Purity:100% - 99.69%Color and Shape:SolidMolecular weight:520.5Ref: TM-T2263
1mg40.00€2mg52.00€5mg82.00€10mg123.00€25mg212.00€50mg343.00€100mg505.00€1mL*10mM (DMSO)88.00€Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurity:98.21% - 98.76%Color and Shape:Colorless Crystals SolidMolecular weight:265.33Entrectinib
CAS:Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C31H34F2N6O2Purity:98.03% - 99.61%Color and Shape:SolidMolecular weight:560.64Ref: TM-T3678
2mg42.00€5mg59.00€10mg88.00€25mg111.00€50mg168.00€100mg283.00€500mg692.00€1mL*10mM (DMSO)69.00€PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formula:C19H16N4O3Purity:96.59% - 99.3%Color and Shape:SolidMolecular weight:348.36Salinomycin sodium salt
CAS:Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.Formula:C42H69NaO11Purity:98.76% - 99.11%Color and Shape:White Or Light Yellow Crystalline Powder With Special SmelMolecular weight:772.98Resveratrol analog 1
CAS:Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.Formula:C14H11FO2Purity:98.42%Color and Shape:SolidMolecular weight:230.23PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg51.00€10mg73.00€25mg140.00€50mg207.00€100mg368.00€200mg547.00€500mg877.00€1mL*10mM (DMSO)57.00€C646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formula:C24H19N3O6Purity:98% - 99.21%Color and Shape:SolidMolecular weight:445.42Bromhexine hydrochloride
CAS:Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.Formula:C14H21Br2ClN2Purity:99.98%Color and Shape:White SolidMolecular weight:412.59ALLO-1
CAS:ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.Formula:C17H15ClN2O2Purity:98%Color and Shape:SolidMolecular weight:314.77Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formula:C20H21N5O6Purity:98.1% - 99.92%Color and Shape:Similar To White PowderMolecular weight:427.413,3'-Diindolylmethane
CAS:3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.Formula:C17H14N2Purity:100%Color and Shape:SolidMolecular weight:246.31Peretinoin
CAS:Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.Formula:C20H30O2Purity:97.23%Color and Shape:SolidMolecular weight:302.45Ref: TM-TQ0064
1mg40.00€2mg51.00€5mg88.00€10mg126.00€25mg230.00€50mg401.00€100mg597.00€500mg1,283.00€1mL*10mM (DMSO)87.00€Tenovin-1
CAS:Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.Formula:C20H23N3O2SPurity:99.33%Color and Shape:SolidMolecular weight:369.48Sevelamer hydrochloride
CAS:Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorptionFormula:(C3H7N·C3H5ClO·HCl)xPurity:98%Color and Shape:SolidMolecular weight:186.08NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99%Color and Shape:SolidMolecular weight:380.24Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purity:99.55% - 99.55%Color and Shape:White To Off-White SolidMolecular weight:407.04Luteolin
CAS:Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.Formula:C15H10O6Purity:96.61% - 98%Color and Shape:SolidMolecular weight:286.24Bakuchiol
CAS:Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Formula:C18H24OPurity:98.69% - 99.47%Color and Shape:Brownish Yellow Liquid ViscousMolecular weight:256.38Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formula:C19H20F2N4O4Purity:97.63% - 99.99%Color and Shape:SolidMolecular weight:406.38Ref: TM-T6927
1mg56.00€5mg119.00€10mg187.00€25mg378.00€50mg605.00€100mg852.00€500mg1,700.00€1mL*10mM (DMSO)131.00€XRK3F2
CAS:XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.Formula:C23H24ClF2NO3Purity:98.75% - 98.91%Color and Shape:SolidMolecular weight:435.89STF-31
CAS:STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Formula:C23H25N3O3SPurity:99.55% - 99.98%Color and Shape:SolidMolecular weight:423.53Ref: TM-T2363
1mg38.00€2mg50.00€5mg81.00€10mg113.00€25mg230.00€50mg437.00€100mg640.00€500mg1,349.00€1mL*10mM (DMSO)106.00€Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formula:C33H40N2O9Purity:98.85% - 99.81%Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Molecular weight:608.68Nifedipine
CAS:Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.Formula:C17H18N2O6Purity:99.39% - 99.49%Color and Shape:Yellow Crystals Physical Description Odorless Yellow Crystals Or Powder Tasteless (Ntp 1992)Molecular weight:346.33Vinorelbine ditartrate
CAS:Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity. Cost-effective and quality-assured.Formula:C45H54N4O8·2C4H6O6Purity:98% - 99.86%Color and Shape:White To Off-White Crystalline PowderMolecular weight:1079.11Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.Formula:C27H45NO2Purity:98.38% - 99.98%Color and Shape:SolidMolecular weight:415.65Proflavine Hemisulfate
CAS:Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formula:C13H12N3O2S0Purity:99.55%Color and Shape:Orange To Red PowderMolecular weight:258.29CGI-1746
CAS:CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Formula:C34H37N5O4Purity:97.69% - 97.88%Color and Shape:SolidMolecular weight:579.69Aumitin
CAS:Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.Formula:C24H20ClN5OPurity:99.13%Color and Shape:SolidMolecular weight:429.9Ref: TM-T14346
1mg65.00€5mg150.00€10mg219.00€25mg395.00€50mg552.00€100mg775.00€200mg1,026.00€1mL*10mM (DMSO)164.00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purity:100% - 99.66%Color and Shape:Yellow SolidMolecular weight:267.28Ref: TM-T2623
5mg40.00€10mg52.00€25mg82.00€50mg106.00€100mg177.00€200mg264.00€500mg444.00€1mL*10mM (DMSO)58.00€NSC 185058
CAS:NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.Formula:C11H9N3SPurity:99.27%Color and Shape:SolidMolecular weight:215.27Tubastatin A Hydrochloride
CAS:Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).Formula:C20H21N3O2·HClPurity:97.24% - 99.15%Color and Shape:SolidMolecular weight:371.86Ezetimibe
CAS:Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formula:C24H21F2NO3Purity:97.28% - 99.97%Color and Shape:SolidMolecular weight:409.43Ref: TM-T1593
1g283.00€10mg48.00€25mg62.00€50mg77.00€100mg87.00€200mg125.00€500mg197.00€1mL*10mM (DMSO)55.00€Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37Irinotecan
CAS:Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formula:C33H38N4O6Purity:100% - 99.92%Color and Shape:SolidMolecular weight:586.68Indole-3-Glyoxylyl Chloride
CAS:Indole-3-glyoxylyl chloride (3-Indoleglyoxylyl chloride) can be used in chemical synthesis, such as bisindolylmaleimide.Formula:C10H6ClNO2Purity:99.72%Color and Shape:Yellow To Orange Powder Or CrystalsMolecular weight:207.61Ref: TM-T0618
1mg97.00€2mg145.00€5mg235.00€10mg394.00€25mg825.00€50mg1,349.00€100mg2,175.00€1mL*10mM (DMSO)379.00€Urolithin A
CAS:Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formula:C13H8O4Purity:99.14% - 99.66%Color and Shape:SolidMolecular weight:228.2Ref: TM-T7174
5mg49.00€10mg72.00€25mg130.00€50mg187.00€100mg320.00€200mg472.00€500mg753.00€1mL*10mM (DMSO)50.00€Peiminine
CAS:1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.Formula:C27H43NO3Purity:99.52% - ≥95%Color and Shape:White PowderMolecular weight:429.64PF-543 hydrochloride
CAS:PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formula:C27H32ClNO4SPurity:98.90% - 99.93%Color and Shape:SolidMolecular weight:502.1SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formula:C23H14ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:404.82Ref: TM-T5173
1mg39.00€5mg87.00€10mg140.00€25mg271.00€50mg386.00€100mg540.00€200mg735.00€1mL*10mM (DMSO)93.00€Topotecan hydrochloride
CAS:Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formula:C23H24ClN3O5Purity:97.88% - 98.71%Color and Shape:White Crystalline SolidMolecular weight:457.92Ref: TM-T1174
1g512.00€5mg35.00€10mg51.00€25mg80.00€50mg107.00€100mg144.00€500mg344.00€1mL*10mM (DMSO)55.00€AL 8697
CAS:AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formula:C21H21F3N4OPurity:98.96% - 99.26%Color and Shape:SolidMolecular weight:402.41Ref: TM-T10277
1mg70.00€5mg145.00€10mg207.00€25mg348.00€50mg495.00€100mg678.00€500mgTo inquire1mL*10mM (DMSO)169.00€Pterostilbene
CAS:Pterostilbene is extracted from Pterocarpus indicus.Formula:C16H16O3Purity:99.20%Color and Shape:Off-White Crystalline PowderMolecular weight:256.3Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47KM11060
CAS:KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormula:C19H17Cl2N3O2SPurity:98.86%Color and Shape:SolidMolecular weight:422.33Salvianolic acid B
CAS:Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.Formula:C36H30O16Purity:99.76% - 99.86%Color and Shape:Yellow SolidMolecular weight:718.61YM-201636
CAS:YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formula:C25H21N7O3Purity:93.28% - 98.3%Color and Shape:SolidMolecular weight:467.48Ref: TM-T6110
1mg48.00€2mg64.00€5mg96.00€10mg173.00€25mg359.00€50mg562.00€100mg802.00€500mg1,644.00€1mL*10mM (DMSO)97.00€Ambroxol hydrochloride
CAS:Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formula:C13H18Br2N2O·HClPurity:99.70%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:414.56Ref: TM-T5S2358
1mg57.00€2mg81.00€5mg111.00€10mg160.00€25mg263.00€50mg378.00€100mg558.00€200mg797.00€1mL*10mM (DMSO)123.00€PF-06447475
CAS:PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.Formula:C17H15N5OPurity:98.61% - 99.62%Color and Shape:SolidMolecular weight:305.33DC661
CAS:DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formula:C31H39Cl2N5Purity:99.07%Color and Shape:SolidMolecular weight:552.58Ref: TM-T5538
1mg80.00€2mg105.00€5mg188.00€10mg319.00€25mg545.00€50mg780.00€100mg1,074.00€1mL*10mM (DMSO)230.00€Olanzapine
CAS:Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formula:C17H20N4SPurity:100% - ≥95%Color and Shape:Yellowish Crystalline PowderMolecular weight:312.43sbp-7455
CAS:SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.Formula:C16H17F3N4O2Purity:97.90% - 99.03%Color and Shape:SolidMolecular weight:354.33Doxorubicin
CAS:Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formula:C27H29NO11Purity:99.31%Color and Shape:Red Crystalline Solid SolidMolecular weight:543.52RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purity:97.76% - 98.85%Color and Shape:SolidMolecular weight:292.37Ref: TM-T1798
1mg35.00€2mg46.00€5mg66.00€10mg96.00€25mg188.00€50mg344.00€100mg509.00€200mg715.00€500mg1,093.00€1mL*10mM (DMSO)89.00€5-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purity:99.31% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2(-)-Epigallocatechin
CAS:(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting theirFormula:C15H14O7Purity:98.83% - 99.76%Color and Shape:White PowderMolecular weight:306.27OSI-027
CAS:OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formula:C21H22N6O3Purity:97.42%Color and Shape:SolidMolecular weight:406.44Ref: TM-T6319
1mg42.00€2mg52.00€5mg86.00€10mg138.00€25mg248.00€50mg389.00€100mg567.00€1mL*10mM (DMSO)88.00€FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formula:C24H23N3O3S3Purity:98.05%Color and Shape:SolidMolecular weight:497.65Ref: TM-T11256
1mg52.00€5mg116.00€10mg182.00€25mg306.00€50mg442.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)128.00€MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Ref: TM-T5494
1mg39.00€5mg96.00€10mg153.00€25mg305.00€50mg454.00€100mg655.00€500mg1,406.00€1mL*10mM (DMSO)114.00€Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formula:C22H23N3O7SPurity:99.33% - 99.51%Color and Shape:Off-White SolidMolecular weight:473.5Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormula:C25H35N7O9S4Purity:99.63%Color and Shape:SolidMolecular weight:705.85Bicyclol
CAS:Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.Formula:C19H18O9Purity:99.48% - 99.88%Color and Shape:SolidMolecular weight:390.34Ref: TM-T4121
5mg63.00€10mg88.00€25mg192.00€50mg354.00€100mg518.00€500mg1,111.00€1mL*10mM (DMSO)63.00€Vismodegib
CAS:Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).Formula:C19H14Cl2N2O3SPurity:98% - 99.99%Color and Shape:SolidMolecular weight:421.3URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purity:98.43% - 99.32%Color and Shape:SolidMolecular weight:421.54Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formula:C26H52N6O11SPurity:94.68% - 99.80%Color and Shape:SolidMolecular weight:656.79Paclitaxel
CAS:Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.Formula:C47H51NO14Purity:98% - 99.92%Color and Shape:White PowderMolecular weight:853.91Danthron
CAS:Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.Formula:C14H8O4Purity:99.97%Color and Shape:Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)Molecular weight:240.21PATULIN
CAS:Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.Formula:C7H6O4Purity:99.91%Color and Shape:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallineMolecular weight:154.12Ref: TM-T3936
1mg79.00€5mg210.00€10mg349.00€25mgTo inquire50mgTo inquire100mg2,619.00€1mL*10mM (DMSO)120.00€CZC-25146
CAS:CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formula:C22H25FN6O4SPurity:97.68%Color and Shape:SolidMolecular weight:488.54Topotecan
CAS:Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.Formula:C23H23N3O5Purity:95.19% - 97.58%Color and Shape:Light Yellow Needle Crystal Or Crystalline PowderMolecular weight:421.45Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formula:C28H28ClNO4SPurity:98% - 99.81%Color and Shape:Light Yellow SolidMolecular weight:510.044FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21P62-mediated mitophagy inducer
CAS:P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy .Formula:C14H9IN4O2Purity:98.96%Color and Shape:SolidMolecular weight:392.15Ref: TM-T13809
1mg35.00€5mg70.00€10mg96.00€25mg202.00€50mg329.00€100mg527.00€200mg750.00€1mL*10mM (DMSO)81.00€Aloe emodin
CAS:Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).Formula:C15H10O5Purity:97.00%Color and Shape:Orange SolidMolecular weight:270.24Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61Tetrahydrocurcumin
CAS:Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formula:C21H24O6Purity:99.37%Color and Shape:Solid PowderMolecular weight:372.41GNE-7915
CAS:GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formula:C19H21F4N5O3Purity:98% - ≥95%Color and Shape:SolidMolecular weight:443.4Ref: TM-T1945
5mg47.00€10mg62.00€25mg114.00€50mg187.00€100mg316.00€200mg410.00€500mg680.00€1mL*10mM (DMSO)50.00€Arctigenin
CAS:(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formula:C21H24O6Purity:98% - 99.51%Color and Shape:SolidMolecular weight:372.41Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:420.63Ref: TM-T1789
5mg48.00€10mg52.00€25mg82.00€50mg99.00€100mg163.00€200mg274.00€500mg505.00€1mL*10mM (DMSO)49.00€Berberine hydrogen sulphate
CAS:Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.Formula:C20H19NO8SPurity:99% - 99.79%Color and Shape:Yellow Crystals Off-White To Yellow PowderMolecular weight:433.43U0126-EtOH
CAS:U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).Formula:C18H16N6S2·C2H6OPurity:98.65% - 99.82%Color and Shape:SolidMolecular weight:426.6Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurity:100% - 99.68%Color and Shape:SolidMolecular weight:506.03MK-2206 dihydrochloride
CAS:MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormula:C25H23Cl2N5OPurity:99.228% - 99.91%Color and Shape:SolidMolecular weight:480.39Ref: TM-T1952
2mg35.00€5mg51.00€10mg70.00€25mg96.00€50mg144.00€100mg216.00€200mg354.00€500mg582.00€1mL*10mM (DMSO)56.00€SG31
SG31 is a potent activator of autophagy, exerting its effects through the AMPK/ULK1-dependent pathway.Formula:C26H37N6O8PColor and Shape:SolidMolecular weight:592.58Notoginsenoside Fc
CAS:1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.Formula:C58H98O26Purity:99.22% - 99.94%Color and Shape:SolidMolecular weight:1211.38Salbutamol hemisulfate
CAS:Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Formula:C13H21NO3H2O4SPurity:99.35%Color and Shape:White Or Almost White Odourless PowderMolecular weight:576.7HDAC-IN-62
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively.Formula:C15H14N2O3SPurity:98%Color and Shape:SolidMolecular weight:302.35PD-166866
CAS:PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formula:C20H24N6O3Purity:98.29%Color and Shape:SolidMolecular weight:396.44Amsacrine hydrochloride
CAS:Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formula:C21H20ClN3O3SPurity:99.05% - 99.92%Color and Shape:SolidMolecular weight:429.92
