Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formula:C18H14N2O4Purity:95.85% - 99.22%Color and Shape:SolidMolecular weight:322.31Ref: TM-T1848
5mg49.00€10mg79.00€25mg140.00€50mg259.00€100mg374.00€200mg560.00€500mg883.00€1mL*10mM (DMSO)87.00€Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formula:C14H12O4Purity:98.66% - 99.57%Color and Shape:Light Tan To Yellow PowderMolecular weight:244.24Isoliquiritigenin
CAS:Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.Formula:C15H12O4Purity:97.61% - 99.44%Color and Shape:PowderMolecular weight:256.25GNE0877
CAS:GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Formula:C14H16F3N7Purity:98.01% - 99.96%Color and Shape:SolidMolecular weight:339.32Ref: TM-T6031
1mg47.00€2mg60.00€5mg119.00€10mg187.00€25mg376.00€50mg562.00€100mg802.00€500mg1,644.00€1mL*10mM (DMSO)96.00€ZSTK474
CAS:PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potentialFormula:C19H21F2N7O2Purity:98.29% - 99.76%Color and Shape:White PowderMolecular weight:417.41Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purity:100% - 99.76%Color and Shape:SolidMolecular weight:425.42Ref: TM-T6130
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg208.00€50mg313.00€100mg465.00€1mL*10mM (DMSO)87.00€Rutin
CAS:Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, andFormula:C27H30O16Purity:95.66% - 97.19%Color and Shape:SolidMolecular weight:610.52Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formula:C26H22N2O2Purity:99.52% - 99.96%Color and Shape:SolidMolecular weight:394.47Ref: TM-T6671
2mg43.00€5mg58.00€10mg93.00€25mg178.00€50mg343.00€100mg509.00€500mg1,121.00€1mL*10mM (DMSO)58.00€Cryptotanshinone
CAS:Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.Formula:C19H20O3Purity:97.69% - ≥95%Color and Shape:Orange Needle CrystalMolecular weight:296.36Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is a metabolite of artemisinin.Formula:C15H24O5Purity:99.41% - 99.72%Color and Shape:White SolidMolecular weight:284.35Paeonol
CAS:Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.Formula:C9H10O3Purity:98.55% - 99.56%Color and Shape:White To Beige Crystalline PowderMolecular weight:166.17MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurity:100%Color and Shape:SolidMolecular weight:461.94Retro-2
CAS:Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.Formula:C19H16N2OSPurity:98.15%Color and Shape:SolidMolecular weight:320.41Parthenolide
CAS:Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C15H20O3Purity:99.10% - 99.46%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:248.32NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formula:C27H45IN2Purity:98.60%Color and Shape:SolidMolecular weight:524.56Ref: TM-T6605
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg264.00€50mg454.00€100mg655.00€1mL*10mM (DMSO)87.00€Cobaltic Protoporphyrin IX chloride
CAS:Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activities.Formula:C34H32ClCoN4O4Purity:≥95.0%Color and Shape:SolidMolecular weight:655.03Autophagy-IN-7
CAS:Autophagy-IN-7 is an autophagy inhibitor that can be used in tumor research.Formula:C15H11N7Color and Shape:SolidMolecular weight:289.295VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purity:100% - 99%Color and Shape:SolidMolecular weight:404.32TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Ranolazine dihydrochloride
CAS:Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Formula:C24H35Cl2N3O4Purity:100% - 99.96%Color and Shape:White Crystalline PowderMolecular weight:500.46BRD5631
CAS:BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway.Formula:C30H35N3O4Purity:98%Color and Shape:SolidMolecular weight:501.62GDC-0349
CAS:GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Formula:C24H32N6O3Purity:96.00% - 98.98%Color and Shape:SolidMolecular weight:452.55Ref: TM-T6510
2mg39.00€5mg66.00€10mg107.00€25mg215.00€50mg324.00€100mg462.00€500mgTo inquire1mL*10mM (DMSO)70.00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:100% - 98.11%Color and Shape:SolidMolecular weight:718.08Ref: TM-T1773
1g467.00€5mg40.00€10mg59.00€25mg87.00€50mg107.00€100mg140.00€200mg188.00€500mg313.00€1mL*10mM (DMSO)66.00€mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21kaempferide
CAS:kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formula:C16H12O6Purity:98.31% - 99.66%Color and Shape:SolidMolecular weight:300.26SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formula:C24H28Cl2N2O4Purity:97.98% - ≥95%Color and Shape:SolidMolecular weight:479.4Clinofibrate
CAS:Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formula:C28H36O6Purity:99.84%Color and Shape:White Crystalline PowderMolecular weight:468.58XCT790
CAS:XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formula:C23H13F9N4O3SPurity:99% - 99.74%Color and Shape:SolidMolecular weight:596.42Pregnenolone
CAS:Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.Formula:C21H32O2Purity:100% - 99.5%Color and Shape:SolidMolecular weight:316.48Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity againstFormula:C66H76Cl3N9O24Purity:97.20% - 99.19%Color and Shape:Off White PowderMolecular weight:1485.71Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purity:98.56% - 99.05%Color and Shape:SolidMolecular weight:383.46Ref: TM-T2277
2mg35.00€5mg52.00€10mg78.00€25mg139.00€50mg225.00€100mg406.00€500mg920.00€1mL*10mM (DMSO)55.00€Lanatoside C
CAS:Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.Formula:C49H76O20Purity:100% - 99.8%Color and Shape:SolidMolecular weight:985.12Doramapimod
CAS:Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formula:C31H37N5O3Purity:97.73% - 98.80%Color and Shape:SolidMolecular weight:527.66Ref: TM-T6277
1g562.00€5mg37.00€10mg55.00€25mg79.00€50mg92.00€100mg127.00€200mg225.00€500mg379.00€1mL*10mM (DMSO)44.00€QN523
CAS:QN523 has drug-like traits, kills cancer cells in vitro, effective in vivo against pancreatic cancer, works via autophagy.Formula:C14H10N4OPurity:97.26%Color and Shape:SolidMolecular weight:250.26Ref: TM-T64374
1mg35.00€5mg74.00€10mg105.00€25mg207.00€50mg325.00€100mg469.00€200mg650.00€1mL*10mM (DMSO)71.00€Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purity:98.91% - 99.49%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21Tigecycline
CAS:Tigecycline (GAR-936), a broad-spectrum glycylcycline, disrupts protein synthesis by binding the 30S ribosomal subunit.Formula:C29H39N5O8Purity:100% - 99.94%Color and Shape:PowderMolecular weight:585.65Ref: TM-T1569
5mg38.00€10mg57.00€25mg79.00€50mg105.00€100mg168.00€200mg248.00€500mg418.00€1mL*10mM (DMSO)59.00€Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purity:94.54% - 98.1%Color and Shape:SolidMolecular weight:338.35QX77
CAS:QX77 is a chaperone-mediated autophagy (CMA) activator.Formula:C16H13ClN2O2Purity:98.21%Color and Shape:SolidMolecular weight:300.74Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formula:C24H25ClFN5O3Purity:97.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Ref: TM-T21312
5mg35.00€10mg51.00€25mg86.00€50mg115.00€100mg144.00€200mg177.00€500mg300.00€1mL*10mM (DMSO)52.00€p62-ZZ Ligand-Linker Conjugate 1
CAS:p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204.Formula:C31H42N2O6Color and Shape:SolidMolecular weight:538.68Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purity:97.72% - 99.41%Color and Shape:SolidMolecular weight:207.27Vps34-PIK-III
CAS:Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.Formula:C17H17N7Purity:98.39% - 98.43%Color and Shape:SolidMolecular weight:319.36Ref: TM-T6945
1mg51.00€2mg71.00€5mg116.00€10mg202.00€25mg454.00€50mg663.00€100mg944.00€500mg1,890.00€1mL*10mM (DMSO)116.00€Nitrendipine
CAS:Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.Formula:C18H20N2O6Purity:99.54% - 99.55%Color and Shape:SolidMolecular weight:360.36Ref: TM-T0119
1g437.00€10mg38.00€25mg55.00€50mg71.00€100mg119.00€200mg175.00€500mg283.00€1mL*10mM (DMSO)55.00€HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formula:C23H22N4O3S2Purity:99.77% - 99.86%Color and Shape:SolidMolecular weight:466.58Ref: TM-T6855
1mg40.00€2mg51.00€5mg84.00€10mg96.00€25mg187.00€50mg329.00€100mg567.00€1mL*10mM (DMSO)84.00€Veliparib dihydrochloride
CAS:Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formula:C13H18Cl2N4OPurity:97.09% - 98%Color and Shape:SolidMolecular weight:317.21Danshensu sodium salt
CAS:Danshensu sodium salt (Sodium Danshensu) is sodium salt of danshensu from the widely used Chinese herb Danshen.Formula:C9H9NaO5Purity:97.04% - 99.52%Color and Shape:SolidMolecular weight:220.16LRRK2 inhibitor 1
CAS:LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.Formula:C20H23N5O4Purity:99.73%Color and Shape:SolidMolecular weight:397.43Ref: TM-T11878
1mg74.00€2mg97.00€5mg160.00€10mg264.00€25mg557.00€50mg944.00€100mg1,491.00€1mL*10mM (DMSO)170.00€Chloroquine phosphate
CAS:Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is used as an autophagy inhibitor. Chloroquine also is an inhibitor of TLRs.Formula:C18H26CLN3·2(H3PO4)Purity:99.64% - ≥95%Color and Shape:White To Slightly Yellow Crystalline Powder White SolidMolecular weight:515.87SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purity:97.03% - 99.89%Color and Shape:SolidMolecular weight:317.34Andrographolide
CAS:Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potentialFormula:C20H30O5Purity:100% - 99.97%Color and Shape:PowderMolecular weight:350.45L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formula:C20H14ClN3OPurity:≥95%Color and Shape:SolidMolecular weight:347.86-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:100% - 98.75%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19Quisinostat dihydrochloride
CAS:Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性,高效的 pan-HDAC 抑制剂,具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。Formula:C21H28Cl2N6O2Purity:97.13%Color and Shape:SolidMolecular weight:467.39Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purity:100% - 99.84%Color and Shape:SolidMolecular weight:228.2Everolimus
CAS:Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.Formula:C53H83NO14Purity:97.76% - 99.52%Color and Shape:Off-White To Light Yellow PowdMolecular weight:958.22Ref: TM-T1784
5mg44.00€10mg55.00€25mg82.00€50mg96.00€100mg120.00€200mg177.00€500mg298.00€1mL*10mM (DMSO)55.00€Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Formula:C7H5NaO3Purity:99.36% - 99.77%Color and Shape:White Solid AmorphousMolecular weight:160.11Cilofexor
CAS:Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formula:C28H22Cl3N3O5Purity:99.32% - ≥95%Color and Shape:SolidMolecular weight:586.85Ref: TM-T7436
1mg50.00€2mg73.00€5mg124.00€10mg188.00€25mg380.00€50mg567.00€100mg807.00€500mg1,644.00€1mL*10mM (DMSO)158.00€Rosolutamide
CAS:Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formula:C28H32O6Purity:96.54% - 99.36%Color and Shape:SolidMolecular weight:464.55Pantoprazole Sodium Hydrate
CAS:Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormula:C16H14F2N3NaO4SH2OPurity:98.32%Color and Shape:SolidMolecular weight:432.37Di-N-desethyl amiodarone hydrochloride
CAS:Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formula:C21H22ClI2NO3Purity:98%Color and Shape:SolidMolecular weight:625.67Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purity:98.42% - 99%Color and Shape:SolidMolecular weight:344.32UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purity:99.82%Color and Shape:SolidMolecular weight:436.58Ref: TM-T17209
1mg35.00€2mg52.00€5mg74.00€10mg119.00€25mg243.00€50mg406.00€100mg607.00€1mL*10mM (DMSO)86.00€NDBM
NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screeningFormula:C33H35BrN4O7Purity:98%Color and Shape:SolidMolecular weight:679.56Magnolol
CAS:Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Formula:C18H18O2Purity:99.49%Color and Shape:A Bioactive Compound Found In The Bark Of The Houpu MagnoliaMolecular weight:266.33CUR5g
CAS:CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formula:C22H20N2O2Purity:98.92%Color and Shape:SolidMolecular weight:344.41Ref: TM-T73550
1mg92.00€5mg216.00€10mg344.00€25mg692.00€50mg1,103.00€100mg1,644.00€1mL*10mM (DMSO)240.00€ATG7-IN-1
CAS:ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.Formula:C17H19FN6O5S2Purity:100% - 100%Color and Shape:SolidMolecular weight:470.5BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62Resatorvid
CAS:Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.Formula:C15H17ClFNO4SPurity:100% - 99.9%Color and Shape:SolidMolecular weight:361.82Ref: TM-TQ0181
1mg49.00€2mg70.00€5mg96.00€10mg164.00€25mg306.00€50mg502.00€100mg805.00€1mL*10mM (DMSO)116.00€Polydatin
CAS:Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.Formula:C20H22O8Purity:97.2% - 98.83%Color and Shape:White Fine PowderMolecular weight:390.38LC3-mHTT-IN-AN2
CAS:LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formula:C15H10O4Purity:≥98%Color and Shape:SolidMolecular weight:254.24Clemastine fumarate
CAS:Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.Formula:C25H30ClNO5Purity:99.52% - 99.8%Color and Shape:Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline PowderMolecular weight:459.97Rabusertib
CAS:Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.Formula:C18H22BrN5O3Purity:98.86% - 99.63%Color and Shape:SolidMolecular weight:436.3Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88Ref: TM-T10990
1mg58.00€5mg111.00€10mg160.00€25mg264.00€50mg396.00€100mg563.00€1mL*10mM (DMSO)124.00€ATG16L1 stabilizer-1
ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent stabilizer of ATG16L1 that enhances cellular autophagy (Autophagy). Regardless of the presence of FKBP12, it has an inhibitory EC50 value of 12.1 μM for ATG16L1. When used alone, ATG16L1 stabilizer-1 can induce GFP-LC3 puncta formation, with an EC50 value of 12.0 μM.Formula:C45H62N14O5SColor and Shape:SolidMolecular weight:911.13Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purity:95.87% - 99.36%Color and Shape:SolidMolecular weight:622.83Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:100% - 99.64%Color and Shape:White Crystalline PowderMolecular weight:1030.29Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purity:96.01% - ≥98%Color and Shape:SolidMolecular weight:394.47Ref: TM-T6055
1mg59.00€2mg86.00€5mg124.00€10mg213.00€25mg331.00€50mg427.00€100mg607.00€1mL*10mM (DMSO)139.00€Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26Aceglutamide
CAS:Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory.Formula:C7H12N2O4Purity:99.56% - 99.77%Color and Shape:SolidMolecular weight:188.18Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57Nortriptyline hydrochloride
CAS:Nortriptyline HCl, a metabolite of amitriptyline, treats major and atypical depression, dysthymia.Formula:C19H22ClNPurity:100% - ≥95%Color and Shape:SolidMolecular weight:299.84MTP
CAS:MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.Formula:C29H23F3N4O2Purity:98%Color and Shape:SolidMolecular weight:516.51GC7 Sulfate
CAS:GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.Formula:C8H22N4O4SPurity:100% - 99.85%Color and Shape:SolidMolecular weight:270.35Ref: TM-T6S1784
1mg37.00€5mg74.00€10mg97.00€25mg157.00€50mg224.00€100mg335.00€200mg497.00€1mL*10mM (DMSO)81.00€LYS01
CAS:LYS01 free base is a new lysosomal autophagy inhibitor.Formula:C23H23Cl2N5Purity:98.28%Color and Shape:SolidMolecular weight:440.37Lumefantrine
CAS:Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formula:C30H32Cl3NOPurity:98.36%Color and Shape:Yellow SolidMolecular weight:528.94Aliskiren hemifumarate
CAS:Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.Formula:C30H53N3O6C4H4O4Purity:96.18% - 99.21%Color and Shape:SolidMolecular weight:1219.6Zoledronic Acid
CAS:Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐,能抑制破骨细胞的分化和凋亡,具有高效的抗骨质再吸收活性,也有抗癌作用。Formula:C5H10N2O7P2Purity:98% - 99.93%Color and Shape:White Crystalline PowderMolecular weight:272.09GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormula:C31H39N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:541.69Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormula:C7H8N4O2Purity:99.47% - 99.97%Color and Shape:White Solid PowderMolecular weight:180.16Chenodeoxycholic acid
CAS:Chenodeoxycholic acid (CDCA), a bile acid, usually conjugated with either glycine or taurine, acts as a detergent to solubilize fats for intestinal absorption.Formula:C24H40O4Purity:99.70% - 99.72%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Monacolin J
CAS:Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Formula:C19H28O4Purity:98.06%Color and Shape:SolidMolecular weight:320.42Ref: TM-T12092
1mg79.00€5mg160.00€10mg235.00€25mg398.00€50mg567.00€100mg820.00€1mL*10mM (DMSO)170.00€Purmorphamine
CAS:Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.Formula:C31H32N6O2Purity:97.19% - 99.48%Color and Shape:Light Tan SolidMolecular weight:520.62Glyphosate
CAS:Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.Formula:C3H8NO5PPurity:99.42% - 99.79%Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Molecular weight:169.07Itraconazole
CAS:Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Formula:C35H38Cl2N8O4Purity:98% - 99.90%Color and Shape:Off-White Crystalline SolidMolecular weight:705.63CZC-25146 hydrochloride
CAS:CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.Formula:C22H26ClFN6O4SPurity:98.76%Color and Shape:SolidMolecular weight:525CX546
CAS:CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formula:C14H17NO3Purity:99.75%Color and Shape:SolidMolecular weight:247.29Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formula:C30H48O3Purity:99.12% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.7
