Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Dinoprost
CAS:Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formula:C20H34O5Purity:≥98%Color and Shape:White To Off-White Crystalline SolidMolecular weight:354.48Ref: TM-T15133
5mg51.00€10mg79.00€25mg144.00€50mg216.00€100mg344.00€200mg512.00€1mL*10mM (DMSO)57.00€Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35Elexacaftor
CAS:Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Formula:C26H34F3N7O4SPurity:98.87% - 99.87%Color and Shape:SolidMolecular weight:597.65Ref: TM-T14935
1mg87.00€2mg137.00€5mg243.00€10mg393.00€25mg772.00€50mg1,074.00€100mg1,444.00€1mL*10mM (DMSO)320.00€TFEB activator 1
CAS:TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer'sFormula:C19H18O3Purity:98.87%Color and Shape:SolidMolecular weight:294.34AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formula:C27H30FN5O3Purity:99.37%Color and Shape:SolidMolecular weight:491.56Ref: TM-T14381
1mg73.00€5mg160.00€10mg250.00€25mg507.00€50mg737.00€100mg1,026.00€1mL*10mM (DMSO)170.00€SR10067
CAS:SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Formula:C31H31NO3Purity:99.88%Color and Shape:SolidMolecular weight:465.58Ref: TM-T12998
1mg58.00€5mg134.00€10mg207.00€25mg353.00€50mg510.00€100mg658.00€200mg905.00€1mL*10mM (DMSO)144.00€Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purity:98.1% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09Naringin
CAS:Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Formula:C27H32O14Purity:99.23%Color and Shape:Beige Creamish Powder Solid Solid Particulate/PowderMolecular weight:580.53FMK 9a
CAS:FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formula:C23H21FN2O3Purity:98.97%Color and Shape:SolidMolecular weight:392.42Ref: TM-T15303
1mg139.00€5mg329.00€10mg494.00€25mg800.00€50mg1,103.00€100mg1,491.00€500mg2,973.00€1mL*10mM (DMSO)284.00€GPP78
CAS:GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.Formula:C27H29N5OPurity:98%Color and Shape:SolidMolecular weight:439.55MRT67307
CAS:Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formula:C26H36N6O2Purity:99.25% - 99.79%Color and Shape:SolidMolecular weight:464.6Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purity:98.67%Color and Shape:SolidMolecular weight:487.93Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Paroxetine hydrochloride
CAS:Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.Formula:C19H21ClFNO3Purity:98% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:365.826Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:100% - 99.91%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g615.00€5mg52.00€10mg65.00€25mg82.00€50mg97.00€100mg145.00€200mg227.00€500mg418.00€1mL*10mM (DMSO)59.00€Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formula:C27H29NO11·HClPurity:98% - 99.36%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.99Calmidazolium chloride
CAS:Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formula:C31H23Cl7N2OPurity:98.06%Color and Shape:SolidMolecular weight:687.7Ref: TM-T10667
5mg63.00€10mg87.00€25mg145.00€50mg215.00€100mg320.00€200mg467.00€1mL*10mM (DMSO)95.00€PF-4708671
CAS:PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formula:C19H21F3N6Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:390.41Procainamide hydrochloride
CAS:Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analogFormula:C13H21N3O·HClPurity:99.83% - 99.97%Color and Shape:White To Slightly Yellow PowderMolecular weight:271.79Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formula:C15H12O4Purity:100% - 99.61%Color and Shape:SolidMolecular weight:256.25Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purity:≥98%Color and Shape:Brown PowderMolecular weight:676.83Rutin hydrate
CAS:Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formula:C27H32O17Purity:97.23%Color and Shape:SolidMolecular weight:628.53Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formula:C25H38O5Purity:98.54% - 99.13%Color and Shape:SolidMolecular weight:418.57Ref: TM-T0687
10mg43.00€25mg58.00€50mg69.00€100mg106.00€200mg140.00€500mg270.00€1mL*10mM (DMSO)47.00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.5Atorvastatin
CAS:Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formula:C33H35FN2O5Purity:99.37% - 99.69%Color and Shape:SolidMolecular weight:558.64Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Formula:C16H12O5Purity:97.1% - 98.97%Color and Shape:SolidMolecular weight:284.26BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formula:C10H9NO2SPurity:97.91% - 99.92%Color and Shape:SolidMolecular weight:207.25Ref: TM-T1902
5mg50.00€10mg57.00€25mg96.00€50mg170.00€100mg265.00€200mg399.00€500mg662.00€1mL*10mM (DMSO)52.00€CCG-1423
CAS:CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formula:C18H13ClF6N2O3Purity:99.80%Color and Shape:SolidMolecular weight:454.75CXM102
CXM102 is an activator of autophagy. This compound induces autophagy in aged BMSCs, rejuvenating them and promoting their preferential differentiation into osteoblasts. CXM102 enhances the nuclear translocation of transcription factor EB (TFEB) and the formation of osteoblasts. In middle-aged male mice, it stimulates bone anabolic metabolism, reduces marrow adipocytes, delays bone loss, lowers serum inflammation levels, reduces organ fibrosis, and extends lifespan.Formula:C28H27NO3Color and Shape:SolidMolecular weight:425.52Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:SolidMolecular weight:450.34GW 4064
CAS:GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).Formula:C28H22Cl3NO4Purity:97.47% - 99.94%Color and Shape:SolidMolecular weight:542.84Ref: TM-T2233
5mg50.00€10mg84.00€25mg139.00€50mg235.00€100mg424.00€200mg640.00€500mg1,008.00€1mL*10mM (DMSO)63.00€Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formula:C9H13N3O5Purity:99.83% - 99.93%Color and Shape:Fine Off-White Crystalline PowderMolecular weight:243.22Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purity:97.14%Color and Shape:White Crystalline PowderMolecular weight:446.52Adenosine
CAS:Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.Formula:C10H13N5O4Purity:98.76% - 99.86%Color and Shape:Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Molecular weight:267.24Glucosamine sulfate
CAS:Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.25ML327
CAS:ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formula:C19H18N4O4Purity:99.48%Color and Shape:SolidMolecular weight:366.37Sorafenib tosylate
CAS:Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formula:C21H16ClF3N4O3·C7H8O3SPurity:99.2% - 99.94%Color and Shape:White To Off-White Crystalline PowderMolecular weight:637.03Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36GSK2606414
CAS:GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor.Cost-effective and quality-assured.Formula:C24H20F3N5OPurity:100% - 98.63%Color and Shape:SolidMolecular weight:451.44Erythromycin ethylsuccinate
CAS:Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.Formula:C43H75NO16Purity:77% - 98%Color and Shape:White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline SolidMolecular weight:862.05GSK3-IN-3
CAS:GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.Formula:C24H35N3O4Purity:99.37%Color and Shape:SolidMolecular weight:429.55Mocetinostat
CAS:Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formula:C23H20N6OPurity:99% - 99.21%Color and Shape:SolidMolecular weight:396.44Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purity:98.29% - 99.59%Color and Shape:Dark Purple Crystalline PowderMolecular weight:651.94LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurity:99.45%Color and Shape:SolidMolecular weight:474.91Ref: TM-T4398
2mg37.00€5mg52.00€10mg84.00€25mg137.00€50mg229.00€100mg340.00€200mg472.00€1mL*10mM (DMSO)58.00€Perphenazine
CAS:Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.Formula:C21H26ClN3OSPurity:99.3% - 99.72%Color and Shape:SolidMolecular weight:403.97Naproxen sodium
CAS:Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Formula:C14H13NaO3Purity:99.68% - 99.79%Color and Shape:White PowderMolecular weight:252.24Rapamycin
CAS:Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.Formula:C51H79NO13Purity:97.08% - 99.03%Color and Shape:Yellow SolidMolecular weight:914.17Ref: TM-T1537
1g283.00€10mg35.00€25mg48.00€50mg52.00€100mg69.00€200mg106.00€500mg188.00€1mL*10mM (DMSO)50.00€Nimodipine
CAS:Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Formula:C21H26N2O7Purity:99.64% - 99.79%Color and Shape:SolidMolecular weight:418.44Thiamet G
CAS:Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal -hexosaminidase.Formula:C9H16N2O4SPurity:99.74% - 99.76%Color and Shape:SolidMolecular weight:248.3Ref: TM-T6056
2mg44.00€5mg63.00€10mg93.00€25mg188.00€50mg343.00€100mg510.00€500mg1,130.00€1mL*10mM (DMSO)63.00€Fluoxetine
CAS:Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formula:C17H18F3NOPurity:99.07% - 99.28%Color and Shape:SolidMolecular weight:309.33Rottlerin
CAS:Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formula:C30H28O8Purity:97.41% - 99.44%Color and Shape:Orange To Brown PowderMolecular weight:516.54Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purity:98% - 99.92%Color and Shape:Light Yellow PowderMolecular weight:610.74SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formula:C28H30ClN5O4SPurity:98.62% - 99.44%Color and Shape:Orange PowderMolecular weight:568.09Ref: TM-T6154
1mg47.00€2mg59.00€5mg97.00€10mg150.00€25mg283.00€50mg465.00€100mg688.00€1mL*10mM (DMSO)150.00€EACC
CAS:EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.Formula:C13H11N3O6S2Purity:98.89%Color and Shape:SolidMolecular weight:369.37AZ PFKFB3 26
CAS:AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.Formula:C24H26N4O2Purity:98.91%Color and Shape:SolidMolecular weight:402.49GSK4112
CAS:GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formula:C18H21ClN2O4SPurity:99.63%Color and Shape:SolidMolecular weight:396.89Silmitasertib sodium salt
CAS:Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Formula:C19H11ClN3NaO2Purity:99.49% - 99.62%Color and Shape:SolidMolecular weight:371.75Ataluren
CAS:Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formula:C15H9FN2O3Purity:99.16% - 99.84%Color and Shape:SolidMolecular weight:284.24Ref: TM-T1805
5mg38.00€10mg57.00€25mg93.00€50mg124.00€100mg188.00€200mg225.00€500mg379.00€1mL*10mM (DMSO)48.00€Streptozocin
CAS:Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation.Formula:C8H15N3O7Purity:100% - 99.56%Color and Shape:Pale Yellow Crystalline PowderMolecular weight:265.22Bergenin
CAS:Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.Formula:C14H16O9Purity:99.55% - 99.60%Color and Shape:The Loose White Needle Crystal Powder Or CrystallineMolecular weight:328.27NL-1
CAS:NL-1 is a mitoNEET inhibitor with antileukemic effect.Formula:C18H25NO3SPurity:98.64%Color and Shape:SolidMolecular weight:335.46PH-797804
CAS:PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.Formula:C22H19BrF2N2O3Purity:97.79% - 97.90%Color and Shape:SolidMolecular weight:477.3Ref: TM-T1974
1mg46.00€5mg94.00€10mg144.00€25mg255.00€50mg406.00€100mg628.00€500mg1,320.00€1mL*10mM (DMSO)97.00€Purvalanol A
CAS:Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Formula:C19H25ClN6OPurity:98.13% - 98.91%Color and Shape:PowderMolecular weight:388.89Quinacrine dihydrochloride
CAS:Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFormula:C23H30CLN3O·2HClPurity:98.24% - 99.72%Color and Shape:Yellow Crystals Or PowderMolecular weight:472.88Avermectin B1
CAS:Avermectin B1 is served as anthelmintic and insecticide.Formula:C48H72O14Purity:mixture - mixtureColor and Shape:White PowderMolecular weight:873.09ICCB-19 hydrochloride
CAS:ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formula:C12H22ClN3OSPurity:99.30%Color and Shape:SolidMolecular weight:291.84Ref: TM-T8931L
5mg35.00€10mg52.00€25mg96.00€50mg145.00€100mg210.00€200mg313.00€500mg495.00€1mL*10mM (DMSO)35.00€Sertindole
CAS:Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Formula:C24H26ClFN4OPurity:99.74%Color and Shape:Off-White To Pale Yellow SolidMolecular weight:440.94Ruxolitinib
CAS:Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formula:C17H18N6Purity:100% - 99.99%Color and Shape:SolidMolecular weight:306.36Ref: TM-T1829
5mg58.00€10mg74.00€25mg92.00€50mg116.00€100mg155.00€200mg245.00€500mg414.00€1mL*10mM (DMSO)65.00€Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormula:C16H12O5Purity:96.26% - ≥98%Color and Shape:Pale-Yellow NeedlesMolecular weight:284.26WYE-354
CAS:WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formula:C24H29N7O5Purity:97.86% - 99.61%Color and Shape:SolidMolecular weight:495.53N6-Isopentenyladenosine
CAS:N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.Formula:C15H21N5O4Purity:99.51%Color and Shape:SolidMolecular weight:335.36Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formula:C11H12Cl2N2O5Purity:99.6% - 99.84%Color and Shape:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidMolecular weight:323.13EB-42486
CAS:EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Formula:C22H22N8OPurity:98.06%Color and Shape:SolidMolecular weight:414.46Ref: TM-T39972
1mg70.00€2mg93.00€5mg156.00€10mg226.00€25mg409.00€50mg610.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)170.00€Sanguinarine
CAS:Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.Formula:C20H14NO4Purity:99.04% - 99.18%Color and Shape:SolidMolecular weight:332.33Regorafenib Hydrochloride
CAS:Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formula:C21H16Cl2F4N4O3Purity:99.56%Color and Shape:SolidMolecular weight:519.289-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purity:99.32%Color and Shape:SolidMolecular weight:404.35Ref: TM-T14066
1mg49.00€2mg70.00€5mg99.00€10mg163.00€25mg325.00€50mg472.00€100mg705.00€1mL*10mM (DMSO)116.00€N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formula:C25H37NOPurity:98.00% - 99.92%Color and Shape:SolidMolecular weight:367.57Ref: TM-TN1965
1mg88.00€5mg187.00€10mg281.00€25mg475.00€50mg692.00€100mg935.00€200mg1,264.00€1mL*10mM (DMSO)188.00€Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5Melatonin
CAS:Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formula:C13H16N2O2Purity:98% - 99.79%Color and Shape:Pale Yellow Leaflets From Benzene SolidMolecular weight:232.28Triclosan
CAS:Triclosan (Irgasan) is an antibacterial and antifungal agent.Formula:C12H7Cl3O2Purity:99.63%Color and Shape:White Solid CrystallineMolecular weight:289.54Galangin
CAS:Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.Formula:C15H10O5Purity:98.24% - 99.93%Color and Shape:Yellowish Needle-Like CrystalMolecular weight:270.24Briciclib
CAS:Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formula:C19H23O10PSPurity:98% - 99.84%Color and Shape:SolidMolecular weight:474.42Ref: TM-T3207
1mg47.00€2mg57.00€5mg88.00€10mg126.00€25mg250.00€50mg376.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)87.00€PFE-360
CAS:PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).Formula:C16H16N6OPurity:98.14% - 99.73%Color and Shape:SolidMolecular weight:308.34Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:464.82Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01Bacilotetrin C analogue
Bacilotetrin C analogue is a variant of Bacilotetrin C. It exhibits cytotoxicity against the triple-negative breast cancer cell line MDA-MB-231, with an IC50 of 0.48 μM. This compound induces autophagy (autophagy) in tumor cells and possesses antitumor activity.Formula:C44H76N6O10Color and Shape:SolidMolecular weight:849.11Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurity:99.76%Color and Shape:SolidMolecular weight:523.75Ref: TM-T8946
1mg58.00€5mg111.00€10mg170.00€25mg284.00€50mg393.00€100mg552.00€200mg748.00€1mL*10mM (DMSO)129.00€Hesperetin
CAS:Hesperetin belongs to the flavanone class of flavonoids.Formula:C16H14O6Purity:99.27%Color and Shape:SolidMolecular weight:302.28SN-38
CAS:SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).Formula:C22H20N2O5Purity:98% - 99.97%Color and Shape:Light-Yellow SolidMolecular weight:392.44,4'-Dimethoxychalcone
CAS:4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.Formula:C17H16O3Purity:99.57%Color and Shape:SolidMolecular weight:268.31Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formula:C25H28N8O2Purity:99.15% - 99.95%Color and Shape:SolidMolecular weight:472.54FTO-IN-10
FTO-IN-10 (compound 7), a potent inhibitor of the human demethylase FTO (fat mass and obesity-associated protein), exhibits an IC50 of 4.5 μM.Purity:98%Color and Shape:Odour SolidBIX 02565
CAS:BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Formula:C26H30N6O2Purity:97.44% - 99.61%Color and Shape:SolidMolecular weight:458.56Felodipine
CAS:Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.Formula:C18H19Cl2NO4Purity:99.91%Color and Shape:SolidMolecular weight:384.25Ref: TM-T0145
5mg51.00€10mg82.00€25mg124.00€50mg180.00€100mg264.00€200mg398.00€500mg647.00€1mL*10mM (DMSO)90.00€(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurity:97.57% - ≥95%Color and Shape:SolidMolecular weight:456.99Ref: TM-T2110
1mg35.00€2mg44.00€5mg60.00€10mg79.00€25mg96.00€50mg144.00€100mg188.00€200mg283.00€500mg512.00€1mL*10mM (DMSO)66.00€ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formula:C22H24Cl2N2O4Purity:97.86% - 99.27%Color and Shape:SolidMolecular weight:451.34Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494Binimetinib
CAS:Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formula:C17H15BrF2N4O3Purity:100% - 99%Color and Shape:SolidMolecular weight:441.23Hydroxychloroquine sulfate
CAS:Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.Formula:C18H26ClN3O·H2SO4Purity:98.92% - 99.88%Color and Shape:Odorless SolidMolecular weight:433.95
