Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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VISTA-IN-2
CAS:VISTA-IN-2 (Compound 1) is a V-domain Ig suppressor of T-cell activation (VISTA) inhibitor that promotes the degradation of VISTA in cells via autophagy,Formula:C23H23N3OPurity:98%Color and Shape:SolidMolecular weight:357.45Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurity:98% - 99.75%Color and Shape:SolidMolecular weight:393.49Ref: TM-T1825
1mg38.00€2mg49.00€5mg70.00€10mg88.00€25mg164.00€50mg224.00€100mg393.00€1mL*10mM (DMSO)70.00€TA-01
CAS:TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Formula:C20H12F3N3Purity:98.77% - 99.94%Color and Shape:SolidMolecular weight:351.32Ref: TM-T4645
2mg35.00€5mg52.00€10mg85.00€25mg156.00€50mg235.00€100mg329.00€200mg464.00€1mL*10mM (DMSO)71.00€10074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purity:97.22% - 99.67%Color and Shape:SolidMolecular weight:332.31Ref: TM-T3686
2mg42.00€5mg63.00€10mg88.00€25mg142.00€50mg225.00€100mg396.00€200mg565.00€500mg900.00€1mL*10mM (DMSO)69.00€Temozolomide
CAS:Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity.Formula:C6H6N6O2Purity:98% - 99.87%Color and Shape:Off-White To Light-Pink Crystalline SolidMolecular weight:194.15Ref: TM-T1178
1g236.00€10mg49.00€25mg74.00€50mg89.00€100mg96.00€200mg127.00€500mg166.00€1mL*10mM (DMSO)59.00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purity:98.81% - 99.18%Color and Shape:SolidMolecular weight:624.77Metyrapone
CAS:Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.Formula:C14H14N2OPurity:99.03% - ≥95%Color and Shape:Crystals From Ether & Pentane SolidMolecular weight:226.27Afzelin
CAS:Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-Formula:C21H20O10Purity:98.92% - 99.38%Color and Shape:SolidMolecular weight:432.38DCC-3116
CAS:DCC-3116 is an orally active, selective and potent ULK1/2 inhibitor with anticancer activity.DCC-3116 inhibits autophagy and can be used in cancer research.Formula:C26H36F3N7O2Purity:98.80%Color and Shape:SoildMolecular weight:535.61Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formula:C64H116N22O19Purity:100%Color and Shape:SolidMolecular weight:1497.74Nitroxoline
CAS:Nitroxoline (5-nitroquinolin-8-ol) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found inFormula:C9H6N2O3Purity:97.74% - ≥98%Color and Shape:SolidMolecular weight:190.16Sertaconazole nitrate
CAS:Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.Formula:C20H15Cl3N2OS·HNO3Purity:98.66%Color and Shape:SolidMolecular weight:500.78Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formula:C19H12ClN3O2Purity:98% - 99.90%Color and Shape:SolidMolecular weight:349.77Ref: TM-T2259
1mg40.00€2mg51.00€5mg85.00€10mg125.00€25mg207.00€50mg329.00€100mg520.00€500mg1,111.00€1mL*10mM (DMSO)93.00€Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurity:100% - 99.81%Color and Shape:SolidMolecular weight:259.33Ref: TM-T1847
5mg35.00€10mg49.00€25mg82.00€50mg113.00€100mg170.00€200mg250.00€500mg419.00€1mL*10mM (DMSO)52.00€Scutellarein
CAS:Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.Formula:C15H10O6Purity:98.02% - 99.63%Color and Shape:SolidMolecular weight:286.24LY2183240
CAS:LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).Formula:C17H17N5OPurity:99.26%Color and Shape:SolidMolecular weight:307.35PF-543
CAS:PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.Formula:C27H31NO4SPurity:99.02%Color and Shape:SolidMolecular weight:465.6Ref: TM-T6085
1mg50.00€5mg106.00€10mg156.00€25mg251.00€50mg374.00€100mg557.00€200mg903.00€1mL*10mM (DMSO)124.00€Lumacaftor
CAS:Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.Formula:C24H18F2N2O5Purity:99.48% - 99.68%Color and Shape:SolidMolecular weight:452.41D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formula:C23H18N4O3Purity:99.02% - 99.96%Color and Shape:SolidMolecular weight:398.41Ref: TM-T2449
1mg43.00€2mg55.00€5mg78.00€10mg95.00€25mg159.00€50mg226.00€100mg408.00€200mg597.00€500mg938.00€1mL*10mM (DMSO)86.00€Pennogenin 3-O-β-chacotrioside
CAS:Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.Formula:C45H72O17Purity:99.69% - 99.77%Color and Shape:SolidMolecular weight:885.043PO
CAS:3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.Formula:C13H10N2OPurity:97.76% - 99.67%Color and Shape:SolidMolecular weight:210.23Ref: TM-T22223
5mg57.00€10mg81.00€25mg127.00€50mg188.00€100mg340.00€200mg507.00€500mg807.00€1mL*10mM (DMSO)64.00€Emodin
CAS:Emodin, a plant-derived anthraquinone, inhibits Y cell growth via various signaling pathways.Formula:C15H10O5Purity:94.4% - 98.9%Color and Shape:Physical Description Orange Needles Or Powder (Ntp 1992)Molecular weight:270.24Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purity:97.10% - 99.33%Color and Shape:SolidMolecular weight:558.7EIPA
CAS:EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.Formula:C11H18ClN7OPurity:96.62% - 98.52%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purity:99.14% - 99.32%Color and Shape:SolidMolecular weight:416.46Ref: TM-T6S1917
5mg71.00€10mg96.00€25mg202.00€50mg303.00€100mg452.00€500mg1,035.00€1mL*10mM (DMSO)79.00€Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formula:C15H10Cl2N2O2SPurity:96.57% - 99.6%Color and Shape:SolidMolecular weight:353.22Ref: TM-T1907
5mg47.00€10mg56.00€25mg90.00€50mg153.00€100mg227.00€200mg338.00€500mg558.00€1mL*10mM (DMSO)50.00€Turofexorate Isopropyl
CAS:Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nMFormula:C25H24F2N2O3Purity:99.33% - 99.73%Color and Shape:SolidMolecular weight:438.47ROC-325
CAS:ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.Formula:C28H27ClN4OSPurity:99.26%Color and Shape:SolidMolecular weight:503.06Ref: TM-T16777
1mg35.00€2mg47.00€5mg64.00€10mg97.00€25mg188.00€50mg311.00€100mg449.00€500mgTo inquireOlaparib
CAS:View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formula:C24H23FN4O3Purity:100% - 99.90%Color and Shape:SolidMolecular weight:434.46Autophagy-IN-6
Autophagy-IN-6 (compound 1u) is an inhibitor of lysosomal autophagy that induces the accumulation of the LC3-II protein. Additionally, it exhibits antiproliferative activity.Formula:C28H43N3O3Color and Shape:SolidMolecular weight:469.66MRT68921
CAS:MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.Formula:C25H34N6OPurity:99.23%Color and Shape:SolidMolecular weight:434.58Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formula:C14H24Cl2N2O3Purity:99.58%Color and Shape:Crystalline SolidMolecular weight:339.258Dexamethasone acetate
CAS:Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formula:C24H31FO6Purity:99.22% - 99.65%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:434.5Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69Ref: TM-T6165
10mg47.00€25mg65.00€50mg88.00€100mg119.00€200mg187.00€500mg424.00€1mL*10mM (DMSO)50.00€FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formula:C23H24FN5O2Purity:98.01% - 99.08%Color and Shape:SolidMolecular weight:421.47Etoposide
CAS:Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).Formula:C29H32O13Purity:99.19% - 99.94%Color and Shape:Crystals From Methanol SolidMolecular weight:588.56Diosgenin glucoside
CAS:Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosisFormula:C33H52O8Purity:97.17% - 99.44%Color and Shape:SolidMolecular weight:576.76Leonurine
CAS:Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.Formula:C14H21N3O5Purity:98.55%Color and Shape:White Crystalline PowderMolecular weight:311.33Pentoxifylline
CAS:Pentoxifylline (PTX) stimulates cytokines, inhibits phosphodiesterase, enhances blood flow, and increases cell flexibility.Formula:C13H18N4O3Purity:99.26% - 99.96%Color and Shape:SolidMolecular weight:278.31UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68CCT128930
CAS:'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Formula:C18H20ClN5Purity:99.07% - 99.18%Color and Shape:SolidMolecular weight:341.84Ref: TM-T6303
2mg42.00€5mg65.00€10mg94.00€25mg170.00€50mg273.00€100mg409.00€200mg652.00€1mL*10mM (DMSO)71.00€Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purity:97.82% - 98.49%Color and Shape:SolidMolecular weight:676.66Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow Crystalline PowderMolecular weight:623.14Ref: TM-T0486L
10mg35.00€25mg52.00€50mg69.00€100mg95.00€200mg136.00€500mg268.00€1mL*10mM (DMSO)74.00€Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Formula:C26H30ClN3O6Purity:99.58% - 99.89%Color and Shape:Yellow SolidMolecular weight:515.99Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purity:95.37% - 99.82%Color and Shape:Dark Green To Black SolidMolecular weight:718.79Ref: TM-T3112
1mg40.00€2mg51.00€5mg85.00€10mg115.00€25mg225.00€50mg365.00€100mg462.00€1mL*10mM (DMSO)120.00€BL-918
CAS:BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.Formula:C23H15F8N3OSPurity:99.11% - 99.40%Color and Shape:SolidMolecular weight:533.44Ref: TM-T8322
1mg49.00€2mg70.00€5mg104.00€10mg156.00€25mg284.00€50mg455.00€100mg747.00€500mg1,501.00€1mL*10mM (DMSO)127.00€4E1rcat
CAS:4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formula:C28H18N2O6Purity:99.36%Color and Shape:SolidMolecular weight:478.45Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purity:95.10% - 99.3% （SEC-HPLC）Color and Shape:LiquidMolecular weight:145 kDaTamibarotene
CAS:Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplasticFormula:C22H25NO3Purity:97.22% - 98.2%Color and Shape:Crystalline SolidMolecular weight:351.44Ref: TM-T6694
1g369.00€10mg47.00€25mg64.00€50mg79.00€100mg97.00€200mg153.00€500mg249.00€1mL*10mM (DMSO)47.00€PF-06454589
CAS:PF-06454589 is a potent inhibitor of LRRK2.Formula:C14H16N6OPurity:99.06%Color and Shape:SolidMolecular weight:284.32Ref: TM-T7729
2mg35.00€5mg50.00€10mg80.00€25mg135.00€50mg197.00€100mg306.00€200mg442.00€1mL*10mM (DMSO)55.00€Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purity:96.39% - 99.29%Color and Shape:SolidMolecular weight:394.42Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:100% - 99.93%Color and Shape:SolidMolecular weight:533.95Ancitabine hydrochloride
CAS:Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.Formula:C9H12ClN3O4Purity:99.02% - 99.37%Color and Shape:White SolidMolecular weight:261.66SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purity:99.94% - 99.97%Color and Shape:SolidMolecular weight:264.12Ref: TM-T3155
5mg51.00€10mg73.00€25mg127.00€50mg235.00€100mg452.00€200mg660.00€500mg1,035.00€1mL*10mM (DMSO)51.00€Sapanisertib
CAS:Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formula:C15H15N7OPurity:100% - 99.67%Color and Shape:SolidMolecular weight:309.33Ref: TM-T1838
1mg40.00€2mg51.00€5mg85.00€10mg96.00€25mg160.00€50mg235.00€100mg350.00€500mg838.00€1mL*10mM (DMSO)88.00€DPN
CAS:DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formula:C15H13NO2Purity:99.01%Color and Shape:Off-White SolidMolecular weight:239.27Memantine hydrochloride
CAS:Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.Formula:C12H22ClNPurity:99.56% - 99.96%Color and Shape:Crystalline SolidMolecular weight:215.763Britannin
CAS:Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.Formula:C19H26O7Purity:98% - 98.53%Color and Shape:SolidMolecular weight:366.41Oxyphenisatin acetate
CAS:Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.Formula:C24H19NO5Purity:98% - 98.62%Color and Shape:SolidMolecular weight:401.41Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purity:90.08% - 99.25%Color and Shape:Yellow PowderMolecular weight:446.36Hoechst 33342
CAS:Hoechst 33342: a benzimidazole dye, DNA stain for AT-rich regions, cell-permeable, quantifies DNA in live cells.Formula:C27H28N6OPurity:98.45% - 99.57%Color and Shape:Yellow-Green PowderMolecular weight:452.55Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purity:97.45% - 99.28%Color and Shape:SolidMolecular weight:443.54SBI-0206965
CAS:SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.Formula:C21H21BrN4O5Purity:99.13%Color and Shape:SolidMolecular weight:489.32DAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formula:C23H26F2N2O4Purity:98.06% - 99.81%Color and Shape:White SolidMolecular weight:432.46Ref: TM-T6202
5mg58.00€10mg88.00€25mg165.00€50mg279.00€100mg414.00€200mg517.00€500mg835.00€1mL*10mM (DMSO)59.00€Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.57%Color and Shape:Clear In WaterMolecular weight:367.4SR-3677
CAS:SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).Formula:C22H24N4O4Purity:98.46%Color and Shape:SolidMolecular weight:408.45H-89 dihydrochloride
CAS:H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).Formula:C20H20BrN3O2S·2HClPurity:100% - 99.40%Color and Shape:SolidMolecular weight:519.28Ref: TM-T6250
5mg39.00€10mg58.00€25mg106.00€50mg202.00€100mg344.00€200mg512.00€500mg815.00€1mL*10mM (DMSO)52.00€Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purity:97.09% - 99.60%Color and Shape:Light Yellow SolidMolecular weight:351.4Autogramin-2
CAS:Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by eitherFormula:C21H27N3O4SPurity:96.25%Color and Shape:SolidMolecular weight:417.52AS-605240
CAS:AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).Formula:C12H7N3O2SPurity:97% - 99.91%Color and Shape:SolidMolecular weight:257.27PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Formula:C17H13Br2N5OSPurity:99.43% - 99.60%Color and Shape:SolidMolecular weight:495.19Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formula:C21H20O6Purity:95% - 98.98%Color and Shape:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Molecular weight:368.3799JH-II-127
CAS:JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Formula:C19H21ClN6O3Purity:98.32%Color and Shape:SolidMolecular weight:416.86Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:99.28% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.37MAO-B-IN-26
CAS:MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Formula:C17H12BrNOPurity:98%Color and Shape:SolidMolecular weight:326.19Tea polyphenol
CAS:Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.Formula:C17H19N3OPurity:98%Color and Shape:Yelloish Green Free Flowing PowderMolecular weight:281.36Venetoclax
CAS:Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).Formula:C45H50ClN7O7SPurity:98% - 99.96%Color and Shape:SolidMolecular weight:868.44LY2109761
CAS:LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Formula:C26H27N5O2Purity:97% - 99.83%Color and Shape:SolidMolecular weight:441.52Ref: TM-T2123
2mg47.00€5mg70.00€10mg111.00€25mg188.00€50mg335.00€100mg507.00€200mg730.00€1mL*10mM (DMSO)77.00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Ref: TM-T1792L
5mg35.00€10mg48.00€25mg69.00€50mg88.00€100mg140.00€200mg207.00€500mg348.00€1mL*10mM (DMSO)58.00€Thalidomide
CAS:Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Formula:C13H10N2O4Purity:98.88% - 99.88%Color and Shape:White SolidMolecular weight:258.23Taxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purity:94.91% - 98.9%Color and Shape:Yellowish PowderMolecular weight:304.25Beclin1-ATG14L interaction inhibitor 1
CAS:Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L.Formula:C23H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:468.53Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Formula:C15H24N2OPurity:100% - 97.16%Color and Shape:SolidMolecular weight:248.36SLW131
CAS:SLW131 (Compound 10) is a CCR7 antagonist with strong affinity, showing a Ki of 9.85 nM. It inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM and β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 also suppresses CCL19-induced morphological changes in primary BMDC cells and CCR7-mediated migration of mouse CD4+ T cells.Formula:C21H27N5O5SColor and Shape:SolidMolecular weight:461.535Alginic acid
CAS:Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formula:C14H22O13Purity:≥98%Color and Shape:SolidMolecular weight:398.317GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formula:C21H27N7O3Purity:100% - 98.78%Color and Shape:SolidMolecular weight:425.48Brivanib
CAS:Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormula:C19H19FN4O3Purity:98.87%Color and Shape:SolidMolecular weight:370.38Ref: TM-T6036
1mg47.00€5mg88.00€10mg144.00€25mg259.00€50mg375.00€100mg560.00€200mg815.00€1mL*10mM (DMSO)97.00€SGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Formula:C20H22F3N5OPurity:100% - 99.84%Color and Shape:SolidMolecular weight:405.42Carboplatin
CAS:Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.Formula:C6H12N2O4PtPurity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:371.25Licochalcone A
CAS:Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.Formula:C21H22O4Purity:98.11% - 98.96%Color and Shape:White Crystalline PowderMolecular weight:338.4PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formula:C20H13FN4O2Purity:98.65%Color and Shape:SolidMolecular weight:360.34URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Formula:C20H22N2O3Purity:98.24%Color and Shape:SolidMolecular weight:338.4LRRK2-IN-10
CAS:LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2Formula:C20H15N5OPurity:98%Color and Shape:SolidMolecular weight:341.37LC3-mHTT-IN-AN1
CAS:LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B.Formula:C15H9Br2NO3Purity:97.26%Color and Shape:SolidMolecular weight:411.04Spautin-1
CAS:Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Formula:C15H11F2N3Purity:97.69% - 98.99%Color and Shape:SolidMolecular weight:271.26Nesolicaftor
CAS:Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.Formula:C18H18N4O4Purity:98.64%Color and Shape:SolidMolecular weight:354.36Ref: TM-T16681
1mg96.00€5mg215.00€10mg378.00€25mg650.00€50mg927.00€100mg1,254.00€1mL*10mM (DMSO)236.00€2-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:302.41Schisandrin
CAS:Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.Formula:C24H32O7Purity:98.97% - 99.32%Color and Shape:White PowderMolecular weight:432.51Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Isorhapontigenin
CAS:Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.Formula:C15H14O4Purity:98.49% - 99.85%Color and Shape:Off White Crystals PowerMolecular weight:258.27KB-R7943 mesylate
CAS:KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.Formula:C17H21N3O6S2Purity:99.22% - ≥95%Color and Shape:SolidMolecular weight:427.5Nilotinib
CAS:Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.Formula:C28H22F3N7OPurity:99.61% - 99.83%Color and Shape:Off-White SolidMolecular weight:529.52Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.36Ixazomib citrate
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).Formula:C20H23BCl2N2O9Purity:100% - 98.37%Color and Shape:SolidMolecular weight:517.12Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purity:99.46% - 99.66%Color and Shape:SolidMolecular weight:441.46E-64
CAS:E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.Formula:C15H27N5O5Purity:98% - 99.95%Color and Shape:White SolidMolecular weight:357.41Ref: TM-T6037
2mg37.00€5mg50.00€10mg79.00€25mg140.00€50mg225.00€100mg335.00€500mg790.00€1mL*10mM (DMSO)51.00€Fluoxetine hydrochloride
CAS:Fluoxetine HCl (Lilly110140), a selective serotonin reuptake inhibitor (SSRI), is an antidepressant with fewer side effects.Formula:C17H19ClF3NOPurity:99.6% - 99.98%Color and Shape:White To Off-White Crystalline Solid White To Off-White PowderMolecular weight:345.787Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurity:98.78% - 99.72%Color and Shape:White PowderMolecular weight:437.52Ref: TM-T0097L
10mg49.00€25mg73.00€50mg96.00€100mg145.00€200mg236.00€500mg331.00€1mL*10mM (DMSO)59.00€Lasalocid sodium
CAS:Lasalocid sodium, an antibiotic from Streptomyces lasaliensis, regulates calcium in muscles and is used as a poultry coccidiostat.Formula:C34H53NaO8Purity:97.08% - 98.49%Color and Shape:SolidMolecular weight:612.77Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.Formula:C29H25F4N3O5SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:603.58Ref: TM-T4379
1mg87.00€5mg166.00€10mg248.00€25mg437.00€50mg665.00€100mg1,008.00€200mg1,520.00€500mg2,252.00€1mL*10mM (DMSO)213.00€Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formula:C10H16ClN5Purity:97.11% - 99.23%Color and Shape:Lactic AcidosisMolecular weight:241.72BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76Torkinib
CAS:Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).Formula:C16H16N6OPurity:99.11%Color and Shape:SolidMolecular weight:308.34Ref: TM-T2414
5mg57.00€10mg74.00€25mg96.00€50mg136.00€100mg227.00€200mg338.00€500mg560.00€1mL*10mM (DMSO)63.00€Iohexol
CAS:Iohexol, a contrast agent, has an osmolality of 322-844 mOsm/kg, 1.1-3 times blood plasma's.Formula:C19H26I3N3O9Purity:80.18% - 99.61%Color and Shape:White To Off-White Solid PowderMolecular weight:821.14Soyasapogenol B
CAS:Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.Formula:C30H50O3Purity:99.81% - 99.92%Color and Shape:SolidMolecular weight:458.72PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurity:97.21% - 98.59%Color and Shape:SolidMolecular weight:347.39Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purity:99.19% - 99.68%Color and Shape:SolidMolecular weight:432.46Honokiol
CAS:Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.Formula:C18H18O2Purity:99.65% - 99.94%Color and Shape:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TasteMolecular weight:266.33Calcimycin
CAS:Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.Formula:C29H37N3O6Purity:98%Color and Shape:SolidMolecular weight:523.62Autophagy-lysosome activator-1
Autophagy-lysosome Activator-1 (Compound F1) is an autophagy-lysosome stimulator that effectively induces the degradation of PD-L1 or VISTA in tumor cells.Formula:C17H18N4O2Color and Shape:SolidMolecular weight:310.35Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5SPurity:98.85% - 99.58%Color and Shape:SolidMolecular weight:556.76
