Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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AZD1208
CAS:AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48Ref: TM-T2300
2mg38.00€5mg51.00€10mg74.00€25mg118.00€50mg213.00€100mg378.00€200mg495.00€500mg792.00€1mL*10mM (DMSO)57.00€Sildenafil citrate
CAS:Sildenafil citrate, a PDE5 inhibitor for erectile dysfunction and occasionally pulmonary hypertension.Formula:C28H38N6O11SPurity:99.59% - 99.97%Color and Shape:White SolidMolecular weight:666.7Piperine
CAS:Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.Formula:C17H19NO3Purity:100% - 97.79%Color and Shape:SolidMolecular weight:285.34Cyclovirobuxine D
CAS:Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formula:C26H46N2OPurity:97.78% - 98%Color and Shape:SolidMolecular weight:402.66Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39PTC-209 hydrobromide
CAS:PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results inFormula:C17H13Br2N5OS·HBrPurity:98%Color and Shape:SolidMolecular weight:576.1TWS119
CAS:TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFormula:C18H14N4O2Purity:98.02% - 99.13%Color and Shape:SolidMolecular weight:318.33Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurity:99.74%Color and Shape:Leaves From Petroleum Ether; White-Brown Scales SolidMolecular weight:131.17Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purity:99.04% - 99.3%Color and Shape:SolidMolecular weight:785.01Ref: TM-T3916
1mg35.00€5mg69.00€10mg88.00€25mg144.00€50mg205.00€100mg303.00€500mg735.00€1mL*10mM (DMSO)97.00€CD437
CAS:CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Formula:C27H26O3Purity:98.79% - 99.63%Color and Shape:SolidMolecular weight:398.49Triptonide
CAS:Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formula:C20H22O6Purity:99.11% - 99.64%Color and Shape:White Crystalline PowderMolecular weight:358.39Ref: TM-T5S1058
1mg56.00€5mg114.00€10mg166.00€25mg283.00€50mg454.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)140.00€Hoechst 33342 trihydrochloride
CAS:Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.Formula:C27H31Cl3N6OPurity:98.73% - ≥98%Color and Shape:SolidMolecular weight:561.93TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formula:C20H13F2N3Purity:99.35% - 99.79%Color and Shape:SolidMolecular weight:333.33Ref: TM-T4646
5mg39.00€10mg58.00€25mg104.00€50mg160.00€100mg244.00€500mgTo inquire1mL*10mM (DMSO)43.00€Rosuvastatin
CAS:Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formula:C22H28FN3O6SPurity:95.24% - 99.8%Color and Shape:SolidMolecular weight:481.54Imiquimod
CAS:Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.Formula:C14H16N4Purity:100% - 99.62%Color and Shape:White To Off White Crystalline PowderMolecular weight:240.3SAFit2
CAS:SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51).Cost-effective and quality-assuredFormula:C46H62N2O10Purity:98.24% - 99.96%Color and Shape:SolidMolecular weight:802.99Ref: TM-T16836
1mg92.00€5mg197.00€10mg296.00€25mg504.00€50mg717.00€100mg938.00€200mg1,320.00€1mL*10mM (DMSO)261.00€Azithromycin
CAS:Azithromycin (CP 62993) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.Formula:C38H72N2O12Purity:99.88% - 99.9%Color and Shape:White To Off-White Solid CrystallineMolecular weight:748.98Wogonin
CAS:Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26Oxybenzone
CAS:Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone.Formula:C14H12O3Purity:99.70%Color and Shape:Colorless Crystals Physical Description White To Off-White Or Light Yellow Powder (Ntp 1992)Molecular weight:228.24Glucosamine
CAS:Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.Formula:C6H13NO5Purity:99.80% - 99.80%Color and Shape:CoaMolecular weight:179.17Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formula:C29H31N7O·CH4SO3Purity:100% - 99.97%Color and Shape:White Crystalline PowderMolecular weight:589.71Polyphyllin G
CAS:Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.Formula:C51H84O22Purity:98%Color and Shape:SolidMolecular weight:1049.21PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Formula:C18H11F3N2OPurity:95.49% - 98.58%Color and Shape:SolidMolecular weight:328.29Ref: TM-T3105
1mg35.00€2mg48.00€5mg70.00€10mg96.00€25mg173.00€50mg273.00€100mg432.00€1mL*10mM (DMSO)77.00€Adezmapimod
CAS:Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formula:C21H16FN3OSPurity:99.42% - 99.87%Color and Shape:White SolidMolecular weight:377.43UNC1999
CAS:UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).Formula:C33H43N7O2Purity:100% - 99.49%Color and Shape:SolidMolecular weight:569.74Ref: TM-T3057
1mg37.00€2mg52.00€5mg71.00€10mg97.00€25mg177.00€50mg286.00€100mg515.00€500mg1,130.00€1mL*10mM (DMSO)89.00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purity:99.99%Color and Shape:White Or Off-White PowderMolecular weight:146.14MLi-2
CAS:MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Formula:C21H25N5O2Purity:98.96%Color and Shape:SolidMolecular weight:379.46Ref: TM-T16115
1mg66.00€2mg96.00€5mg133.00€10mg197.00€25mg435.00€50mg658.00€100mg937.00€1mL*10mM (DMSO)142.00€Lycorine hydrochloride
CAS:Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.Formula:C16H18ClNO4Purity:99.45% - 99.49%Color and Shape:Fine Crystal PowderMolecular weight:323.77Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82Ref: TM-T1792
5mg35.00€10mg51.00€25mg80.00€50mg96.00€100mg144.00€200mg185.00€500mg309.00€1mL*10mM (DMSO)57.00€Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:100% - 99.85%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg43.00€2mg56.00€5mg88.00€10mg106.00€25mg213.00€50mg344.00€100mg550.00€1mL*10mM (DMSO)87.00€Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.69%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24KU-55933
CAS:KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.Formula:C21H17NO3S2Purity:100% - 99.80%Color and Shape:SolidMolecular weight:395.49Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purity:99.62% - 99.62%Color and Shape:SolidMolecular weight:246.3Ref: TM-TQ0165
1mg104.00€5mg240.00€10mg360.00€25mg520.00€50mg692.00€100mg1,035.00€1mL*10mM (DMSO)310.00€Lys05
CAS:Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.Formula:C23H26Cl5N5Purity:99.13% - 99.45%Color and Shape:SolidMolecular weight:549.75Salubrinal
CAS:Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formula:C21H17Cl3N4OSPurity:100% - 98.25%Color and Shape:SolidMolecular weight:479.81Ref: TM-T3045
2mg42.00€5mg62.00€10mg93.00€25mg163.00€50mg274.00€100mg465.00€500mg1,035.00€1mL*10mM (DMSO)67.00€yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Formula:C15H14O4Purity:98.82% - 99.55%Color and Shape:Pale Yellow PowderMolecular weight:258.27Ref: TM-T3S0738
1mg70.00€5mg135.00€10mg207.00€25mg349.00€50mg515.00€100mg735.00€1mL*10mM (DMSO)177.00€Rupatadine Fumarate
CAS:Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.Formula:C26H26ClN3·C4H4O4Purity:99.86%Color and Shape:White Or Almost-White PowderMolecular weight:532.03BRD4 degrader-5
BRD4 degrader-5 (Compound 23) is a protein degrader utilizing a hydrophobic tag (HyTag) that targets BRD4 for degradation through endoplasmic reticulum stress and the autophagy-lysosome pathway (DC50 = 24.7 μM). It also inhibits the proliferation of 4T1 cancer cells, with an IC50 of 20.6 μM.Formula:C35H42ClN7O2SColor and Shape:SolidMolecular weight:660.27Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurity:99.79% - 99.84%Color and Shape:SolidMolecular weight:291.37Pirarubicin
CAS:Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.Formula:C32H37NO12Purity:97.61% - 98.27%Color and Shape:Red Crystalline PowderMolecular weight:627.64Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56PR-619
CAS:PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.Formula:C7H5N5S2Purity:100% - 99.10%Color and Shape:SolidMolecular weight:223.28Cabergoline
CAS:Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.Formula:C26H37N5O2Purity:99.86%Color and Shape:White Crystalline SolidMolecular weight:451.6Pemetrexed disodium hemipenta hydrate
CAS:Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formula:C20H21N5O6·2NaH2OPurity:98.76%Color and Shape:SolidMolecular weight:518.43Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:White SolidMolecular weight:345.42Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54Ref: TM-T1961
1mg37.00€5mg74.00€10mg117.00€25mg173.00€50mg236.00€100mg378.00€200mg558.00€1mL*10mM (DMSO)84.00€Juglanin
CAS:Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formula:C20H18O10Purity:98.8% - 99.33%Color and Shape:SolidMolecular weight:418.35Citalopram hydrobromide
CAS:Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormula:C20H22BrFN2OPurity:99.81%Color and Shape:White Crystalline PowderMolecular weight:405.304
