Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Panobinostat
CAS:Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.Formula:C21H23N3O2Purity:97.2% - 99.14%Color and Shape:Yellow SolidMolecular weight:349.43Ref: TM-T2383
5mg38.00€10mg57.00€25mg87.00€50mg105.00€100mg144.00€200mg177.00€500mg364.00€1mL*10mM (DMSO)55.00€Kaempferol
CAS:Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.Formula:C15H10O6Purity:98% - 99.41%Color and Shape:Yellow Needles From Alcohol And Water SolidMolecular weight:286.24Ref: TM-T2177
1g274.00€5mg52.00€25mg39.00€50mg50.00€100mg64.00€200mg89.00€500mg187.00€1mL*10mM (DMSO)55.00€Meglutol
CAS:Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.Formula:C6H10O5Purity:99.73% - 99.94%Color and Shape:SolidMolecular weight:162.14Capivasertib
CAS:Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Formula:C21H25ClN6O2Purity:97.59% - 99.6%Color and Shape:SolidMolecular weight:428.92Ref: TM-T1920
1mg40.00€2mg52.00€5mg70.00€10mg99.00€25mg168.00€50mg246.00€100mg378.00€200mg610.00€1mL*10mM (DMSO)89.00€Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formula:C21H24F3N3SPurity:98.3% - 99.46%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:407.5Erlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4·HClPurity:99.78% - 99.85%Color and Shape:White Or Off-White PowderMolecular weight:429.9Oxyresveratrol
CAS:1.Formula:C14H12O4Purity:98.09% - 99.69%Color and Shape:Yellow SolidMolecular weight:244.24Sodium 4-phenylbutyrate
CAS:Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.Formula:C10H11NaO2Purity:100% - 99.92%Color and Shape:SolidMolecular weight:186.18Resveratrol
CAS:Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities.Formula:C14H12O3Purity:99.53% - 99.9%Color and Shape:Off-White To Tan PowderMolecular weight:228.24Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:SolidMolecular weight:593.22Ref: TM-T1073
5mg38.00€10mg52.00€25mg87.00€50mg117.00€100mg170.00€200mg250.00€500mg424.00€1mL*10mM (DMSO)55.00€Flavopiridol
CAS:Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; also inhibits EGFR, PKA. In Phase 1/2 trials.Formula:C21H20ClNO5Purity:97.74% - 99.86%Color and Shape:SolidMolecular weight:401.84SU9516
CAS:SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formula:C13H11N3O2Purity:100% - 99.68%Color and Shape:SolidMolecular weight:241.25Ref: TM-T6167
1mg35.00€2mg50.00€5mg73.00€10mg103.00€25mg208.00€50mg376.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)74.00€Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purity:99.79%Color and Shape:SolidMolecular weight:428.44A-867744
CAS:A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Formula:C20H19ClN2O3SPurity:95.66%Color and Shape:SolidMolecular weight:402.89MG-132
CAS:View and buy MG-132 from TargetMol.MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).Cited in 50 publications.Formula:C26H41N3O5Purity:95% - 99.99%Color and Shape:White To Off-White PowderMolecular weight:475.62Ref: TM-T2154
10mg48.00€25mg88.00€50mg144.00€100mg216.00€200mg376.00€500mg472.00€1mL*10mM (DMSO)47.00€KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formula:C26H29ClN2O4SPurity:99.78% - 99.86%Color and Shape:White SolidMolecular weight:501.04Ref: TM-T2697
1mg57.00€2mg79.00€5mg113.00€10mg155.00€25mg305.00€50mg378.00€100mg552.00€1mL*10mM (DMSO)127.00€Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purity:98.11% - 98.87%Color and Shape:SolidMolecular weight:578.52BGT226
CAS:BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formula:C28H25F3N6O2Purity:100% - 98.40%Color and Shape:SolidMolecular weight:534.53Ref: TM-T6072L
1mg52.00€5mg114.00€10mg187.00€25mg411.00€50mg607.00€100mg847.00€1mL*10mM (DMSO)156.00€Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47Talarozole
CAS:Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of 5.4/0.46 nM.Formula:C21H23N5SPurity:97.51%Color and Shape:SolidMolecular weight:377.5110058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purity:98% - 99.82%Color and Shape:SolidMolecular weight:249.35BGT226 maleate
CAS:BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .Formula:C28H25F3N6O2·C4H4O4Purity:97.75% - 98.78%Color and Shape:SolidMolecular weight:650.6Ref: TM-T6072
1mg38.00€5mg77.00€10mg114.00€25mg244.00€50mg359.00€100mg512.00€200mg702.00€1mL*10mM (DMSO)99.00€Schizandrin A
CAS:Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μMFormula:C24H32O6Purity:99.91%Color and Shape:SolidMolecular weight:416.51Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32SMER18
CAS:SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.Formula:C16H14ClNO2Purity:97.27%Color and Shape:SolidMolecular weight:287.74Ref: TM-T16900
1mg133.00€5mg329.00€10mg472.00€25mg914.00€50mg1,415.00€100mg1,882.00€1mL*10mM (DMSO)360.00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purity:99.17% - 99.67%Color and Shape:SolidMolecular weight:328.32Adapalene
CAS:Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.Formula:C28H28O3Purity:99.53% - 99.76%Color and Shape:White To Off-White Crystalline PowderMolecular weight:412.52Gemcitabine
CAS:Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4Purity:100% - 99.67%Color and Shape:SolidMolecular weight:263.2Ixazomib
CAS:Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.Formula:C14H19BCl2N2O4Purity:98% - 98.92%Color and Shape:SolidMolecular weight:361.03Ref: TM-T2122
1mg48.00€5mg95.00€10mg127.00€25mg259.00€50mg416.00€100mg652.00€200mg922.00€1mL*10mM (DMSO)97.00€Efavirenz
CAS:Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formula:C14H9ClF3NO2Purity:99.2% - 99.83%Color and Shape:White To Slightly Pink Crystalline PowderMolecular weight:315.67Ref: TM-T2393
1g404.00€5mg42.00€10mg52.00€25mg71.00€50mg89.00€100mg116.00€500mg273.00€1mL*10mM (DMSO)49.00€Acitretin
CAS:Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.Formula:C21H26O3Purity:100% - 98.60%Color and Shape:Crystals From Hexane SolidMolecular weight:326.43DMH-1
CAS:DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formula:C27H20ClFN4O4Purity:100% - 99.82%Color and Shape:SolidMolecular weight:518.92Ref: TM-T2241
5mg55.00€10mg96.00€25mg155.00€50mg226.00€100mg354.00€200mg454.00€500mg743.00€1mL*10mM (DMSO)63.00€CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formula:C22H18Cl2N8Purity:97.94% - ≥95%Color and Shape:SolidMolecular weight:465.34Ref: TM-T2310
2mg43.00€5mg64.00€10mg96.00€25mg160.00€50mg254.00€100mg404.00€200mg603.00€500mg938.00€1mL*10mM (DMSO)70.00€Loperamide hydrochloride
CAS:Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Purity:100% - 99.94%Color and Shape:Crystals Practically Insoluble In WaterMolecular weight:513.498Colchicine
CAS:Colchicine (Colcin) is a natural product that is an inhibitor of microtubule polymerization (IC50=3 nM) and blocks microtubule polymerization by binding toFormula:C22H25NO6Purity:98% - 99.96%Color and Shape:Pale Yellow Scales Or Powder; Pale Yellow Needles When Crystallized From Ethyl Acetate To Light Used To Treat Gouty Arthritis Pseudogout Sarcoidal Arthritis And Calcific Tendinitis (EpaMolecular weight:399.44Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Formula:C9H16ClN3O2Purity:98.36% - 99.44%Color and Shape:Solid SolidMolecular weight:233.7Tempol
CAS:Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formula:C9H18NO2Purity:97% - 99.74%Color and Shape:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMolecular weight:172.25Tanespimycin
CAS:Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69Sedanolide
CAS:Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.Formula:C12H18O2Purity:97.14% - ≥98%Color and Shape:SolidMolecular weight:194.27α-Thujone
CAS:α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formula:C10H16OPurity:98.16% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23GSK621
CAS:GSK621 is a specific and potent AMPK activator.Formula:C26H20ClN3O5Purity:97.02% - 97.05%Color and Shape:SolidMolecular weight:489.91DMOG
CAS:DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14ZLN005
CAS:ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.Formula:C17H18N2Purity:100% - 99.8%Color and Shape:SolidMolecular weight:250.34Ref: TM-T1802
5mg37.00€10mg56.00€25mg90.00€50mg170.00€100mg274.00€200mg411.00€500mg653.00€1mL*10mM (DMSO)40.00€Carprofen
CAS:Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.Formula:C15H12ClNO2Purity:98.99% - 99.65%Color and Shape:SolidMolecular weight:273.71Autogramin-1
CAS:Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.Formula:C23H27N5O5SPurity:97.22% - 98.76%Color and Shape:SolidMolecular weight:485.56Vitexin
CAS:Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.Formula:C21H20O10Purity:99.16% - 99.64%Color and Shape:Yellow PowderMolecular weight:432.38Lithocholic acid
CAS:Lithocholic acid, a bile acid, aids fat absorption, often paired with glycine/taurine, and promotes bile flow.Formula:C24H40O3Purity:99.69% - 99.93%Color and Shape:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Molecular weight:376.57BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purity:99.31% - 99.64%Color and Shape:SolidMolecular weight:490.64Ref: TM-T7697
1mg40.00€2mg51.00€5mg85.00€10mg117.00€25mg207.00€50mg350.00€100mg518.00€200mg740.00€1mL*10mM (DMSO)131.00€Colistin sulfate
CAS:Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Formula:C53H100N16O17SPurity:≥95%Color and Shape:PowderMolecular weight:1253.51
