Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Tubastatin A Hydrochloride
CAS:Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).Formula:C20H21N3O2·HClPurity:97.24% - 99.15%Color and Shape:SolidMolecular weight:371.86Ezetimibe
CAS:Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formula:C24H21F2NO3Purity:97.28% - 99.97%Color and Shape:SolidMolecular weight:409.43Ref: TM-T1593
1g283.00€10mg48.00€25mg62.00€50mg77.00€100mg87.00€200mg125.00€500mg197.00€1mL*10mM (DMSO)55.00€Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37Irinotecan
CAS:Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formula:C33H38N4O6Purity:100% - 99.92%Color and Shape:SolidMolecular weight:586.68Indole-3-Glyoxylyl Chloride
CAS:Indole-3-glyoxylyl chloride (3-Indoleglyoxylyl chloride) can be used in chemical synthesis, such as bisindolylmaleimide.Formula:C10H6ClNO2Purity:99.72%Color and Shape:Yellow To Orange Powder Or CrystalsMolecular weight:207.61Ref: TM-T0618
1mg97.00€2mg145.00€5mg235.00€10mg394.00€25mg825.00€50mg1,349.00€100mg2,175.00€1mL*10mM (DMSO)379.00€Urolithin A
CAS:Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formula:C13H8O4Purity:99.14% - 99.66%Color and Shape:SolidMolecular weight:228.2Ref: TM-T7174
5mg49.00€10mg72.00€25mg130.00€50mg187.00€100mg320.00€200mg472.00€500mg753.00€1mL*10mM (DMSO)50.00€Peiminine
CAS:1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.Formula:C27H43NO3Purity:99.52% - ≥95%Color and Shape:White PowderMolecular weight:429.64PF-543 hydrochloride
CAS:PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formula:C27H32ClNO4SPurity:98.90% - 99.93%Color and Shape:SolidMolecular weight:502.1SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formula:C23H14ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:404.82Ref: TM-T5173
1mg39.00€5mg87.00€10mg140.00€25mg271.00€50mg386.00€100mg540.00€200mg735.00€1mL*10mM (DMSO)93.00€Topotecan hydrochloride
CAS:Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formula:C23H24ClN3O5Purity:97.88% - 98.71%Color and Shape:White Crystalline SolidMolecular weight:457.92Ref: TM-T1174
1g512.00€5mg35.00€10mg51.00€25mg80.00€50mg107.00€100mg144.00€500mg344.00€1mL*10mM (DMSO)55.00€AL 8697
CAS:AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formula:C21H21F3N4OPurity:98.96% - 99.26%Color and Shape:SolidMolecular weight:402.41Ref: TM-T10277
1mg70.00€5mg145.00€10mg207.00€25mg348.00€50mg495.00€100mg678.00€500mgTo inquire1mL*10mM (DMSO)169.00€Pterostilbene
CAS:Pterostilbene is extracted from Pterocarpus indicus.Formula:C16H16O3Purity:99.20%Color and Shape:Off-White Crystalline PowderMolecular weight:256.3Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47KM11060
CAS:KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormula:C19H17Cl2N3O2SPurity:98.86%Color and Shape:SolidMolecular weight:422.33Salvianolic acid B
CAS:Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.Formula:C36H30O16Purity:99.76% - 99.86%Color and Shape:Yellow SolidMolecular weight:718.61YM-201636
CAS:YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formula:C25H21N7O3Purity:93.28% - 98.3%Color and Shape:SolidMolecular weight:467.48Ref: TM-T6110
1mg48.00€2mg64.00€5mg96.00€10mg173.00€25mg359.00€50mg562.00€100mg802.00€500mg1,644.00€1mL*10mM (DMSO)97.00€Ambroxol hydrochloride
CAS:Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formula:C13H18Br2N2O·HClPurity:99.70%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:414.56Ref: TM-T5S2358
1mg57.00€2mg81.00€5mg111.00€10mg160.00€25mg263.00€50mg378.00€100mg558.00€200mg797.00€1mL*10mM (DMSO)123.00€PF-06447475
CAS:PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.Formula:C17H15N5OPurity:98.61% - 99.62%Color and Shape:SolidMolecular weight:305.33DC661
CAS:DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formula:C31H39Cl2N5Purity:99.07%Color and Shape:SolidMolecular weight:552.58Ref: TM-T5538
1mg80.00€2mg105.00€5mg188.00€10mg319.00€25mg545.00€50mg780.00€100mg1,074.00€1mL*10mM (DMSO)230.00€
