Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Topotecan
CAS:Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.Formula:C23H23N3O5Purity:95.19% - 97.58%Color and Shape:Light Yellow Needle Crystal Or Crystalline PowderMolecular weight:421.45Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formula:C28H28ClNO4SPurity:98% - 99.81%Color and Shape:Light Yellow SolidMolecular weight:510.044FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21P62-mediated mitophagy inducer
CAS:P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy .Formula:C14H9IN4O2Purity:98.96%Color and Shape:SolidMolecular weight:392.15Ref: TM-T13809
1mg35.00€5mg70.00€10mg96.00€25mg202.00€50mg329.00€100mg527.00€200mg750.00€1mL*10mM (DMSO)81.00€Aloe emodin
CAS:Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).Formula:C15H10O5Purity:97.00%Color and Shape:Orange SolidMolecular weight:270.24Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61Tetrahydrocurcumin
CAS:Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formula:C21H24O6Purity:99.37%Color and Shape:Solid PowderMolecular weight:372.41GNE-7915
CAS:GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formula:C19H21F4N5O3Purity:98% - ≥95%Color and Shape:SolidMolecular weight:443.4Ref: TM-T1945
5mg47.00€10mg62.00€25mg114.00€50mg187.00€100mg316.00€200mg410.00€500mg680.00€1mL*10mM (DMSO)50.00€Arctigenin
CAS:(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formula:C21H24O6Purity:98% - 99.51%Color and Shape:SolidMolecular weight:372.41Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:420.63Ref: TM-T1789
5mg48.00€10mg52.00€25mg82.00€50mg99.00€100mg163.00€200mg274.00€500mg505.00€1mL*10mM (DMSO)49.00€Berberine hydrogen sulphate
CAS:Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.Formula:C20H19NO8SPurity:99% - 99.79%Color and Shape:Yellow Crystals Off-White To Yellow PowderMolecular weight:433.43U0126-EtOH
CAS:U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).Formula:C18H16N6S2·C2H6OPurity:98.65% - 99.82%Color and Shape:SolidMolecular weight:426.6Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurity:100% - 99.68%Color and Shape:SolidMolecular weight:506.03MK-2206 dihydrochloride
CAS:MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormula:C25H23Cl2N5OPurity:99.228% - 99.91%Color and Shape:SolidMolecular weight:480.39Ref: TM-T1952
2mg35.00€5mg51.00€10mg70.00€25mg96.00€50mg144.00€100mg216.00€200mg354.00€500mg582.00€1mL*10mM (DMSO)56.00€SG31
SG31 is a potent activator of autophagy, exerting its effects through the AMPK/ULK1-dependent pathway.Formula:C26H37N6O8PColor and Shape:SolidMolecular weight:592.58Notoginsenoside Fc
CAS:1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.Formula:C58H98O26Purity:99.22% - 99.94%Color and Shape:SolidMolecular weight:1211.38Salbutamol hemisulfate
CAS:Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Formula:C13H21NO3H2O4SPurity:99.35%Color and Shape:White Or Almost White Odourless PowderMolecular weight:576.7HDAC-IN-62
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively.Formula:C15H14N2O3SPurity:98%Color and Shape:SolidMolecular weight:302.35PD-166866
CAS:PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formula:C20H24N6O3Purity:98.29%Color and Shape:SolidMolecular weight:396.44Amsacrine hydrochloride
CAS:Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formula:C21H20ClN3O3SPurity:99.05% - 99.92%Color and Shape:SolidMolecular weight:429.92
