Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
Sort by
p38-α MAPK-IN-1
CAS:p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.Formula:C27H35N5O3Purity:99.52%Color and Shape:SolidMolecular weight:477.6Ref: TM-T12347
1mg88.00€5mg180.00€10mg281.00€25mg520.00€50mg777.00€100mg1,169.00€200mg1,568.00€1mL*10mM (DMSO)188.00€Cisatracurium besylate
CAS:Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant for intravenous administration.Formula:C53H72N2O12·2C6H5O3SPurity:99.57% - ≥95%Color and Shape:White Or White Powder CategoryMolecular weight:1243.48Ref: TM-T1459
10mg47.00€25mg70.00€50mg111.00€100mg180.00€200mg264.00€500mg452.00€1mL*10mM (DMSO)60.00€4EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formula:C18H12Cl2N4O4SPurity:96.8% - 99.12%Color and Shape:SolidMolecular weight:451.28Ivermectin
CAS:Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.Formula:C48H74O14Purity:94.11% - 97.74%Color and Shape:SolidMolecular weight:875.09IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63Ref: TM-T6176
1mg40.00€2mg52.00€5mg88.00€10mg139.00€25mg245.00€50mg406.00€100mg607.00€200mg845.00€1mL*10mM (DMSO)87.00€AICAR phosphate
CAS:AICAR phosphate (Acadesine phosphate) is an AMPK activator, an inhibitor of autophagy, YAP and mitophagy, and inhibits iNOS production.Formula:C9H14N4O5·xH3O4PPurity:100%Color and Shape:SolidMolecular weight:356.23Milciclib
CAS:Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formula:C25H32N8OPurity:99.28%Color and Shape:SolidMolecular weight:460.57Ref: TM-T6081
1mg51.00€5mg106.00€10mg177.00€25mg376.00€50mg603.00€100mg905.00€200mg1,216.00€1mL*10mM (DMSO)110.00€Prazosin hydrochloride
CAS:Prazosin HCl, a synthetic antiadrenergic, treats hypertension, heart failure, and more by relaxing blood vessels with an unclear mechanism.Formula:C19H22ClN5O4Purity:99.87% - 99.89%Color and Shape:White To Tan Powder Off-White To Yellow PowderMolecular weight:419.86Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purity:98.92% - 99.64%Color and Shape:White Crystal PowderMolecular weight:608.72Ganoderic acid A
CAS:Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formula:C30H44O7Purity:99.31% - ≥95%Color and Shape:SolidMolecular weight:516.67Ref: TM-T6S1141
1mg47.00€5mg97.00€10mg160.00€25mg250.00€50mg374.00€100mg547.00€1mL*10mM (DMSO)110.00€Levosimendan
CAS:Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.Formula:C14H12N6OPurity:99.32% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28LY3009120
CAS:LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.Formula:C23H29FN6OPurity:96.96% - ≥95%Color and Shape:SolidMolecular weight:424.51PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Formula:C29H30ClN5O2SPurity:98.35%Color and Shape:SolidMolecular weight:548.1Ref: TM-T14860
1mg52.00€2mg74.00€5mg119.00€10mg170.00€25mg354.00€50mg550.00€100mg792.00€1mL*10mM (DMSO)144.00€Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purity:100% - 99.74%Color and Shape:SolidMolecular weight:346.42Ref: TM-T4672
1mg96.00€5mg215.00€10mg369.00€25mg610.00€50mg840.00€100mg1,130.00€500mg2,308.00€1mL*10mM (DMSO)235.00€Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formula:C20H19NO3Purity:99.87%Color and Shape:Solid CompactMolecular weight:321.37Naproxen
CAS:Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesicFormula:C14H14O3Purity:99.6% - 99.89%Color and Shape:Crystals From Acetone-Hexane SolidMolecular weight:230.26ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41Gartanin
CAS:Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.Formula:C23H24O6Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:396.43Cinobufagin
CAS:Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.Formula:C26H34O6Purity:97.77% - 98.16%Color and Shape:SolidMolecular weight:442.54Ref: TM-T3432
1mg52.00€5mg96.00€10mg144.00€25mg215.00€50mg298.00€100mg464.00€500mg1,008.00€1mL*10mM (DMSO)96.00€
