Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purity:97.87% - 99.51%Color and Shape:SolidMolecular weight:526.88Ref: TM-T4367
1mg49.00€5mg99.00€10mg168.00€25mg335.00€50mg477.00€100mg662.00€200mg892.00€1mL*10mM (DMSO)116.00€PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurity:99.13% - 99.7%Color and Shape:SolidMolecular weight:369.22Ref: TM-T6932
1mg39.00€2mg49.00€5mg66.00€10mg89.00€25mg155.00€50mg222.00€100mg310.00€1mL*10mM (DMSO)56.00€AC-73
CAS:AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.Formula:C21H21NO2Purity:98.95%Color and Shape:SolidMolecular weight:319.4Ref: TM-T14091
1mg49.00€5mg97.00€10mg173.00€25mg305.00€50mg513.00€100mg909.00€500mg1,825.00€1mL*10mM (DMSO)108.00€EN6
CAS:EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Formula:C19H14F2N4O2Purity:95.16% - 97.04%Color and Shape:SolidMolecular weight:368.34Ref: TM-T11191
1mg47.00€5mg88.00€10mg137.00€25mg205.00€50mg264.00€100mg400.00€500mg909.00€1mL*10mM (DMSO)70.00€Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formula:C23H19F3N4O3Purity:97.53%Color and Shape:SolidMolecular weight:456.421-Monomyristin
CAS:1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFormula:C17H34O4Purity:99.58%Color and Shape:SolidMolecular weight:302.45IITZ-01
CAS:IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Formula:C26H23FN8OPurity:99.31%Color and Shape:SolidMolecular weight:482.51Schisandrin B
CAS:Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.Formula:C23H28O6Purity:100% - 99.84%Color and Shape:SolidMolecular weight:400.46Ref: TM-T2925
1mg42.00€5mg88.00€10mg127.00€25mg230.00€50mg414.00€100mg600.00€500mg1,254.00€1mL*10mM (DMSO)94.00€GNE-9605
CAS:GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).Formula:C17H20ClF4N7OPurity:98.55% - 98.75%Color and Shape:SolidMolecular weight:449.83β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Formula:C15H14O3Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:242.27Ref: TM-T6407
5mg48.00€10mg60.00€25mg97.00€50mg185.00€100mg305.00€200mg460.00€500mg753.00€1mL*10mM (DMSO)63.00€Isotretinoin
CAS:Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promoteFormula:C20H28O2Purity:98.06% - 99.61%Color and Shape:Reddish-Orange Plates From Isopropyl Alcohol (Ntp 1992)Molecular weight:300.44Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purity:96.68% - 98.13%Color and Shape:SolidMolecular weight:320.25Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurity:99.02% - ≥95%Color and Shape:SolidMolecular weight:436.26Cabazitaxel
CAS:Cabazitaxel (XRP6258) is a taxane used for castration-resistant metastatic prostate cancer post-docetaxel failure.Formula:C45H57NO14Purity:98% - 99.93%Color and Shape:SolidMolecular weight:835.93LY2562175
CAS:LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).Formula:C28H27Cl2N3O4Purity:99.16% - 99.78%Color and Shape:SolidMolecular weight:540.44Ref: TM-T15806
1mg104.00€5mg227.00€10mg369.00€25mg740.00€50mg1,169.00€100mg1,568.00€200mg2,118.00€1mL*10mM (DMSO)269.00€Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25Ambroxol
CAS:Ambroxol treats respiratory diseases by thinning mucus. Active in Mucosolvan, it enhances mucus clearance and protects lungs.Formula:C13H18Br2N2OPurity:99.72%Color and Shape:SolidMolecular weight:378.1Gimeracil
CAS:Gimeracil (Gimestat) is a competitive, reversible inhibitor of dihydropyrimidine dehydrogenase.Formula:C5H4ClNO2Purity:99.80%Color and Shape:SolidMolecular weight:145.54Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:100% - 99.97%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg52.00€10mg64.00€25mg80.00€50mg96.00€100mg144.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)52.00€Pogostone
CAS:Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.Formula:C12H16O4Purity:98.46% - 99.03%Color and Shape:SolidMolecular weight:224.25
