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DUB

DUB

DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.

Products of "DUB"

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products per page.Found 54 products on this category.
  • USP7-IN-6

    CAS:
    USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).
    Formula:C41H43N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:729.89

    Ref: TM-T13271

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • USP8-IN-3

    CAS:
    USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D.
    Formula:C18H18F3N5O2S
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:425.43

    Ref: TM-T67873

    1mg
    35.00€
    5mg
    64.00€
    10mg
    97.00€
    25mg
    207.00€
    50mg
    329.00€
    100mg
    475.00€
    500mg
    938.00€
    1mL*10mM (DMSO)
    84.00€
  • P22074

    CAS:
    P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.
    Formula:C12H9NO3S2
    Purity:100%
    Color and Shape:Solid
    Molecular weight:279.33

    Ref: TM-T28284

    1mg
    200.00€
    5mg
    472.00€
    10mg
    645.00€
    25mg
    905.00€
    1mL*10mM (DMSO)
    360.00€
  • ML364

    CAS:
    ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.
    Formula:C24H18F3N3O3S2
    Purity:100% - 99.92%
    Color and Shape:Solid
    Molecular weight:517.54

    Ref: TM-T3555

    5mg
    72.00€
    10mg
    96.00€
    25mg
    175.00€
    50mg
    279.00€
    100mg
    435.00€
    500mg
    935.00€
    1mL*10mM (DMSO)
    82.00€