CaSR
The calcium-sensing receptor (CaSR) is a GPCR that plays a vital role in maintaining calcium homeostasis by regulating parathyroid hormone secretion and calcium reabsorption in the kidneys. CaSR is also involved in various other physiological processes, including bone metabolism and vascular function. Modulators of CaSR are used in the treatment of conditions such as hyperparathyroidism, osteoporosis, and cardiovascular diseases. At CymitQuimica, we provide a selection of high-quality CaSR modulators to support your research in calcium metabolism, endocrinology, and bone health.
Products of "CaSR"
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Found 20 products on this category.
Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Formula:C12H6N2O8S·2SrPurity:98.97%Color and Shape:Crystalline SolidMolecular weight:513.49Calindol hydrochloride
CAS:Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.Formula:C21H21ClN2Purity:99.47%Color and Shape:SolidMolecular weight:336.86Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Formula:C22H23ClF3NPurity:99.9% - 99.94%Color and Shape:Off-White To Tan SolidMolecular weight:393.87Ref: TM-T2406
10mg50.00€25mg70.00€50mg88.00€100mg144.00€200mg185.00€500mg309.00€1mL*10mM (DMSO)52.00€AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.Formula:C17H17NOSPurity:100%Color and Shape:SolidMolecular weight:283.39Ronacaleret HCl
CAS:Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.Formula:C25H32ClF2NO4Purity:99.58%Color and Shape:SolidMolecular weight:483.98Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Formula:C38H73N21O10S2HClPurity:100%Color and Shape:SolidMolecular weight:1353.33SB-423562
CAS:SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formula:C26H32N2O4Purity:98.64%Color and Shape:SolidMolecular weight:436.54Ref: TM-T12846
1mg39.00€5mg85.00€10mg126.00€25mg221.00€50mg338.00€100mg467.00€200mg640.00€1mL*10mM (DMSO)94.00€Strontium chloride
CAS:Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.Formula:Cl2SrPurity:98%Color and Shape:White Solid CrystallineMolecular weight:158.52Poly-D-lysine hydrobromide (MW 30000-70000)
CAS:Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is a peptide CaSR agonist that removes proteinase K-resistant PrP from SN56 neuroblastoma cells.Formula:(C6H14N2O2)x·xHBrColor and Shape:SolidMolecular weight:227.102Tecalcet Hydrochloride
CAS:Tecalcet Hydrochloride, an allosteric CaSR modulator, enhances extracellular Ca2+ sensitivity.Formula:C18H23Cl2NOPurity:99.44%Color and Shape:SolidMolecular weight:340.29Ref: TM-T13918
2mg35.00€5mg49.00€10mg75.00€25mg155.00€50mg244.00€100mg354.00€200mgTo inquire1mL*10mM (DMSO)50.00€NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Formula:C24H25ClN2O2·HClPurity:99.22% - 99.38%Color and Shape:SolidMolecular weight:445.38Ref: TM-T4967
1mg46.00€2mg59.00€5mg92.00€10mg126.00€25mg215.00€50mg339.00€100mg502.00€1mL*10mM (DMSO)90.00€Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFormula:Cl3GdPurity:98%Color and Shape:White Crystalline SolidMolecular weight:263.61Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Formula:C22H22F3NPurity:99.48%Color and Shape:Yellow OilMolecular weight:357.41NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Formula:C19H21N3OPurity:97.13%Color and Shape:SolidMolecular weight:307.39γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Formula:C11H17F3N2O7Color and Shape:SolidMolecular weight:346.26NPS-2143
CAS:NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.Formula:C24H25ClN2O2Purity:98.24%Color and Shape:SolidMolecular weight:408.92Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Formula:C11H15Cl2N3O6SPurity:98.56%Color and Shape:SoildMolecular weight:388.22Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Formula:C33H40O18Purity:98% - 99.92%Color and Shape:SolidMolecular weight:724.66H-Glu-Thr-OH
CAS:H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide composed of two amino acids-glutamic acid (Glu) and threonine (Thr)-linked by a peptide bond and functions as an agonist of the extracellular calcium-sensing receptor (CaSR).Formula:C9H16N2O6Color and Shape:SolidMolecular weight:248.23Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Formula:C24H26N2O2Purity:98.88% - 99.68%Color and Shape:SolidMolecular weight:374.48
