SGLT
Sodium-glucose co-transporters (SGLTs) are membrane proteins that facilitate the reabsorption of glucose in the kidneys by coupling glucose transport with sodium ions. SGLT inhibitors are an important class of drugs used in the treatment of type 2 diabetes, as they help reduce blood glucose levels by preventing glucose reabsorption in the renal tubules. These inhibitors are also being investigated for their potential benefits in cardiovascular and renal protection. At CymitQuimica, we provide a range of high-quality SGLT modulators to support your research in diabetes, renal physiology, and metabolic disorders.
Products of "SGLT"
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Found 29 products on this category.
Ertugliflozin L-pyroglutamic acid
CAS:Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.Formula:C27H32ClNO10Purity:98.71% - 99.84%Color and Shape:SolidMolecular weight:566Ref: TM-T15244
5mg47.00€10mg60.00€25mg89.00€50mg96.00€100mg140.00€200mg198.00€500mg340.00€1mL*10mM (DMSO)52.00€Licogliflozin
CAS:Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).Formula:C23H28O7Purity:98%Color and Shape:SolidMolecular weight:416.46Bexagliflozin
CAS:Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Formula:C24H29ClO7Purity:98.99%Color and Shape:SolidMolecular weight:464.94Ref: TM-T7217
1mg71.00€2mg90.00€5mg136.00€10mg197.00€25mg393.00€50mg582.00€100mg830.00€1mL*10mM (DMSO)144.00€Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Formula:C24H35ClO9Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:502.98KGA-2727
CAS:KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Formula:C26H40N4O8Purity:98.95%Color and Shape:SolidMolecular weight:536.62Ref: TM-T15656
1mg120.00€5mg274.00€10mg454.00€25mg750.00€50mg1,026.00€100mg1,406.00€200mg1,890.00€1mL*10mM (DMSO)323.00€T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Formula:C26H28O11Purity:99.56%Color and Shape:SolidMolecular weight:516.49Ref: TM-T9590
1mg52.00€2mg74.00€5mg96.00€10mg137.00€25mg217.00€50mg391.00€100mg560.00€1mL*10mM (DMSO)134.00€Sergliflozin etabonate
CAS:Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.Formula:C23H28O9Purity:95.59%Color and Shape:SolidMolecular weight:448.46Ref: TM-T28757
1mg185.00€2mg279.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€1mL*10mM (DMSO)490.00€O-Desethyl Dapagliflozin
CAS:O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Formula:C19H21ClO6Purity:97.09%Color and Shape:SolidMolecular weight:380.82Ref: TM-T67849
1mg57.00€5mg120.00€10mg187.00€25mg321.00€50mg470.00€100mg683.00€1mL*10mM (DMSO)135.00€Tofogliflozin (hydrate)
CAS:Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Formula:C22H28O7Purity:97.02% - 98.78%Color and Shape:SolidMolecular weight:404.45Ref: TM-T5016
1mg46.00€2mg59.00€5mg87.00€10mg140.00€25mg259.00€50mg467.00€100mg653.00€200mg927.00€500mg1,359.00€1mL*10mM (DMSO)96.00€Canagliflozin hemihydrate
CAS:Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Formula:C48H52F2O11S2Purity:99.42% - 99.96%Color and Shape:SolidMolecular weight:907.05SGL5213
CAS:SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.Formula:C37H55N3O8Purity:98%Color and Shape:SolidMolecular weight:669.85Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .Formula:C21H24O10Purity:99.58% - 99.76%Color and Shape:Solid CrystallineMolecular weight:436.41Sergliflozin A
CAS:Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Formula:C20H24O7Purity:99.43%Color and Shape:SolidMolecular weight:376.4Canagliflozin
CAS:Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Formula:C24H25FO5SPurity:100% - 99.76%Color and Shape:SolidMolecular weight:444.52Mizagliflozin
CAS:Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Formula:C28H44N4O8Purity:98.32% - 98.66%Color and Shape:SolidMolecular weight:564.67Ref: TM-T16083
1mg81.00€2mg105.00€5mg163.00€10mg274.00€25mg542.00€50mg778.00€100mg1,074.00€1mL*10mM (DMSO)212.00€SGLT inhibitor-1
CAS:SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).Formula:C24H27FO8Purity:98%Color and Shape:SolidMolecular weight:462.46Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormula:C21H24O10Purity:97.16%Color and Shape:SolidMolecular weight:436.41Ref: TM-T2S0731
1mg64.00€5mg124.00€10mg165.00€25mg323.00€50mg487.00€100mg710.00€1mL*10mM (DMSO)137.00€Sotagliflozin
CAS:Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFormula:C21H25ClO5SPurity:99% - 99.78%Color and Shape:SolidMolecular weight:424.94Ref: TM-T3547
1mg46.00€2mg57.00€5mg87.00€10mg131.00€25mg248.00€50mg378.00€100mg560.00€500mg1,198.00€1mL*10mM (DMSO)88.00€Enavogliflozin
CAS:Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Formula:C24H27ClO6Purity:97.81%Color and Shape:SolidMolecular weight:446.92Ref: TM-T38843
1mg156.00€5mg378.00€10mg590.00€25mg1,026.00€50mg1,406.00€100mg1,863.00€1mL*10mM (DMSO)415.00€Ipragliflozin
CAS:Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.Formula:C21H21FO5SPurity:99.38% - 99.70%Color and Shape:SolidMolecular weight:404.45Ertugliflozin
CAS:PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Formula:C22H25ClO7Purity:99.89% - 99.96%Color and Shape:SolidMolecular weight:436.88Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formula:C21H25ClO6Purity:99.5% - 99.74%Color and Shape:SolidMolecular weight:408.87Velagliflozin
CAS:Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2.Formula:C23H25NO5Purity:98%Color and Shape:SolidMolecular weight:395.45Leachianone A
CAS:Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.Formula:C26H30O6Purity:99.79%Color and Shape:SolidMolecular weight:438.51IRAK inhibitor 4 trans
IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.Formula:C33H35F3N6O3Purity:98%Color and Shape:SolidMolecular weight:620.66Phloretin
CAS:Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.Formula:C15H14O5Purity:100% - 99.76%Color and Shape:SolidMolecular weight:274.27Remogliflozin etabonate
CAS:Remogliflozin etabonate is a prodrug SGLT2 inhibitor; Ki for hSGLT2: 1.95μM, rSGLT2: 2.14μM, rSGLT1: 8.57μM, hSGLT1: 43.1μM.Formula:C26H38N2O9Purity:99%Color and Shape:SolidMolecular weight:522.59Ref: TM-T34286
2mg35.00€5mg52.00€10mg96.00€25mg164.00€50mg245.00€100mg340.00€200mg472.00€1mL*10mM (DMSO)62.00€Empagliflozin
CAS:Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.Formula:C23H27ClO7Purity:98% - 99.89%Color and Shape:SolidMolecular weight:450.91Ref: TM-T1766
1g278.00€5mg47.00€10mg60.00€50mg79.00€100mg96.00€200mg144.00€500mg188.00€1mL*10mM (DMSO)50.00€HSK0935
CAS:HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.Formula:C22H25ClO7Purity:98%Color and Shape:SolidMolecular weight:436.88
