
Dopamine Receptor
Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.
Products of "Dopamine Receptor"
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Fallypride
CAS:Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.Formula:C20H29FN2O3Purity:100% - 99.17%Color and Shape:SolidMolecular weight:364.45Ref: TM-T70302
1mg359.00€5mg842.00€10mg1,035.00€25mg1,663.00€50mg2,072.00€100mg2,660.00€1mL*10mM (DMSO)677.00€Loxapine succinate
CAS:Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.Formula:C22H24ClN3O5Purity:99.69%Color and Shape:White To Of-White SolidMolecular weight:445.95-HT7R antagonist 3
CAS:Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.Formula:C30H33FN4O3Color and Shape:SolidMolecular weight:516.61Pericyazine
CAS:Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist.Formula:C21H23N3OSPurity:99.61%Color and Shape:SolidMolecular weight:365.49Ref: TM-T16472
1mg46.00€2mg59.00€5mg93.00€10mg124.00€25mg235.00€50mg389.00€100mg567.00€500mg1,225.00€1mL*10mM (DMSO)77.00€Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purity:99.79% - 99.91%Color and Shape:SolidMolecular weight:298.34Fananserin
CAS:Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formula:C23H24FN3O2SPurity:99.78%Color and Shape:SolidMolecular weight:425.52Ref: TM-T15270
2mg42.00€5mg56.00€10mg81.00€25mg116.00€50mg170.00€100mg250.00€200mg369.00€1mL*10mM (DMSO)62.00€Fipexide
CAS:Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983.Formula:C20H21ClN2O4Purity:99.95%Color and Shape:SolidMolecular weight:388.84Lurasidone
CAS:Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6Formula:C28H36N4O2SPurity:99.5%Color and Shape:SolidMolecular weight:492.68(Rac)-Rotigotine hydrochloride
CAS:(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.Formula:C19H26ClNOSColor and Shape:SolidMolecular weight:351.93Docosahexaenoic acid ethyl ester
CAS:Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina or neurons.Formula:C24H36O2Color and Shape:SolidMolecular weight:356.54Amantadine hydrochloride
CAS:Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.Formula:C10H18ClNPurity:99.98%Color and Shape:Solid CrystallineMolecular weight:187.71Sonepiprazole
CAS:Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociationFormula:C21H27N3O3SPurity:99.31%Color and Shape:SolidMolecular weight:401.52Ref: TM-T23380
2mg38.00€5mg58.00€10mg94.00€25mg180.00€50mg306.00€100mg442.00€200mg622.00€1mL*10mM (DMSO)71.00€UCM-1306
CAS:UCM-1306: an oral dopamine D1 receptor PAM; boosts DA efficacy, may enhance motor and cognitive function in PD.Formula:C14H14FNO2SPurity:100%Color and Shape:SoildMolecular weight:279.33Ansofaxine hydrochloride
CAS:Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).Formula:C24H32ClNO3Purity:99.57% - 99.77%Color and Shape:SolidMolecular weight:417.97Paliperidone
CAS:Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic.Formula:C23H27FN4O3Purity:95% - 99.08%Color and Shape:Off White To Light Orange Coloured SolidMolecular weight:426.48Mesdopetam hemitartrate
CAS:Mesdopetam hemitartrate antagonizes dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM) and stabilizes psychomotor function.Formula:C28H42F2N2O12S2Purity:99.98%Color and Shape:SolidMolecular weight:700.77Lumateperone
CAS:Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Formula:C24H28FN3OPurity:99.77%Color and Shape:SolidMolecular weight:393.5Haloperidol
CAS:Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function.Formula:C21H23ClFNO2Purity:98.69% - 98.97%Color and Shape:Crystals SolidMolecular weight:375.86Moperone
CAS:Moperone (R 1658) is an antagonist of both the D2 dopamine receptor (D2 dopamine receptor) and the D3 dopamine receptor (D3 dopamine receptor), with IC50 values for each of 1.0 nM.Formula:C22H26FNO2Color and Shape:SolidMolecular weight:355.45PD-168077 maleate
CAS:PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)Formula:C24H26N4O5Purity:98.82%Color and Shape:SolidMolecular weight:450.49Ref: TM-T5047
2mg35.00€5mg52.00€10mg80.00€25mg150.00€50mg245.00€100mg364.00€200mg517.00€1mL*10mM (DMSO)58.00€L-745870 hydrochloride
CAS:L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptorFormula:C18H20Cl2N4Purity:97.36%Color and Shape:SolidMolecular weight:363.28Ref: TM-T11799
5mg40.00€10mg65.00€25mg111.00€50mg178.00€100mg259.00€200mg374.00€1mL*10mM (DMSO)34.00€Levosulpiride
CAS:Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.Formula:C15H23N3O4SPurity:98.20% - 99.88%Color and Shape:White Crystalline PowderMolecular weight:341.43Diclofensine hydrochloride
CAS:Diclofensine hydrochloride (Ro 8-4650 hydrochloride) 是一种高效单胺再摄取抑制剂,在大鼠脑突触体中能够阻断多巴胺 (IC50=0.74 nM)、去甲肾上腺素 (IC50=2.3 nM) 和 5-羟色胺 (IC50=3.7 nM)。Formula:C17H18Cl3NOPurity:98.86% - 99.93%Color and Shape:SolidMolecular weight:358.69FAUC 213
CAS:FAUC 213 is a selective full antagonist of the dopamine D4 receptor.Formula:C18H19ClN4Purity:99.84%Color and Shape:SolidMolecular weight:326.82Nomifensine maleate
CAS:Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.Formula:C20H22N2O4Purity:98.46%Color and Shape:SolidMolecular weight:354.4Tolnapersine
CAS:Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.Formula:C21H26N2OPurity:98%Color and Shape:SolidMolecular weight:322.44Clozapine
CAS:Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent.Formula:C18H19ClN4Purity:99.91% - 99.93%Color and Shape:Yellow Crystals From Acetone-Petroleum Ether SolidMolecular weight:326.82Ref: TM-T0455
1g449.00€10mg35.00€25mg52.00€50mg70.00€100mg96.00€200mg170.00€500mg303.00€1mL*10mM (DMSO)47.00€Brexpiprazole HCl
CAS:Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.Formula:C25H27N3O2S·xHClPurity:99.05%Color and Shape:SolidMolecular weight:433.6Ref: TM-T8690
1mg131.00€5mg286.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€500mg2,688.00€1mL*10mM (DMSO)338.00€A-381393
CAS:A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).Formula:C20H24N4Purity:99.00%Color and Shape:SolidMolecular weight:320.43Ref: TM-T5397
1mg40.00€5mg80.00€10mg117.00€25mg210.00€50mg304.00€100mg437.00€200mg615.00€1mL*10mM (DMSO)88.00€Hirsuteine
CAS:Hirsuteine: natural product; blocks nicotine effects on dopamine by hindering ion flow in receptor channels.Formula:C22H26N2O3Purity:99.36% - 99.63%Color and Shape:SolidMolecular weight:366.45Pramipexole dihydrochloride
CAS:Pramipexole dihydrochloride could be used to treat Parkinson disease.Formula:C10H18ClN3SPurity:98%Color and Shape:White Crystalline PowderMolecular weight:247.79D1R antagonist 1
CAS:Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formula:C22H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:448.35Tetrahydropalmatine hydrochloride
CAS:Tetrahydropalmatine HCl (Gindarine) is a muscle relaxant alkaloid from Corydalis plants.Formula:C21H26ClNO4Purity:98% - 99.59%Color and Shape:SolidMolecular weight:391.888PF2562
CAS:PF2562: Dopamine D1 ligand, agonist/partial agonist. Binds D1 receptor (Ki: 113 nM), active in cAMP assay (EC50: 568 nM).Formula:C19H17N5OPurity:98%Color and Shape:SolidMolecular weight:331.37AHN 1-055 hydrochloride
CAS:AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).Formula:C21H24ClF2NOPurity:99.60%Color and Shape:SolidMolecular weight:379.87Ref: TM-T39429
2mg35.00€5mg52.00€10mg80.00€25mg137.00€50mg202.00€100mg311.00€200mg467.00€1mL*10mM (DMSO)52.00€Talipexole dihydrochloride
CAS:Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical andFormula:C10H17Cl2N3SPurity:98.64%Color and Shape:Light Yellow SolidMolecular weight:282.23Ref: TM-T14490
2mg38.00€5mg56.00€10mg89.00€25mg154.00€50mg264.00€100mg424.00€200mg613.00€500mg949.00€1mL*10mM (DMSO)63.00€PNU-96391
CAS:PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.Formula:C15H23NO2SPurity:99.76%Color and Shape:SolidMolecular weight:281.41Ref: TM-T28435
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)235.00€Veralipride
CAS:Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.Formula:C17H25N3O5SPurity:99.65%Color and Shape:SolidMolecular weight:383.46N-0500 HCl
CAS:N-0500 HCl, a potent DA receptor agonist, displaces [3H]DP_x005f_x0002_5,6-ADTN with an IC50 of 3nM.Formula:C15H22ClNO2Purity:98.3% - 98.42%Color and Shape:SolidMolecular weight:283.79SK609 HCl
CAS:SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.Formula:C10H15Cl2NPurity:99.02%Color and Shape:SolidMolecular weight:220.14SCH-23390 maleate
CAS:SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,Formula:C21H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:403.86Flibanserin
CAS:Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.Formula:C20H21F3N4OPurity:99.37% - 99.93%Color and Shape:White PowderMolecular weight:390.4Tetrahydropalmatine
CAS:Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epilepticFormula:C21H25NO4Purity:99.91% - 99.95%Color and Shape:SolidMolecular weight:355.43FGH31
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].Formula:C33H36N4O2Purity:98%Color and Shape:SolidMolecular weight:520.66NGB 2904
CAS:NGB 2904 is a potent and selective antagonist of dopamine D3 receptor. NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).Formula:C28H29Cl2N3OPurity:98.79%Color and Shape:SolidMolecular weight:494.46Ref: TM-T28167
2mg40.00€5mg58.00€10mg90.00€25mg163.00€50mg279.00€100mg394.00€500mgTo inquire1mL*10mM (DMSO)75.00€PD 168568 dihydrochloride
CAS:PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).Formula:C22H29Cl2N3OPurity:99.27%Color and Shape:SolidMolecular weight:422.39Ref: TM-T12383
5mg48.00€10mg58.00€25mg117.00€50mg170.00€100mg248.00€200mg348.00€1mL*10mM (DMSO)60.00€Pimethixene maleate
CAS:Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.Formula:C23H23NO4SPurity:100%Color and Shape:SolidMolecular weight:409.5SCH-23390 hydrochloride
CAS:SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formula:C17H19Cl2NOPurity:98% - 99.51%Color and Shape:SolidMolecular weight:324.24Ref: TM-T4369
1mg39.00€2mg50.00€5mg78.00€10mg97.00€25mg195.00€50mg369.00€100mg550.00€1mL*10mM (DMSO)78.00€Ordopidine
CAS:Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.Formula:C14H20FNO2SPurity:99.52%Color and Shape:SolidMolecular weight:285.38Spiroxatrine
CAS:Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.Formula:C22H25N3O3Purity:99.83%Color and Shape:SolidMolecular weight:379.45