GTPase
GTPases are a family of enzymes that hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP), playing a crucial role in signal transduction pathways, including those mediated by GPCRs. GTPases act as molecular switches in various cellular processes, such as cell division, growth, and differentiation. Dysregulation of GTPase activity is implicated in numerous diseases, including cancer and genetic disorders. At CymitQuimica, we offer a selection of high-quality GTPase modulators to support your research in cell signaling, cancer biology, and GPCR-related pathways.
Products of "GTPase"
Sort by
Found 17 products on this category.
CID-4785700
CAS:CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75Formula:C22H23ClFN3O3Purity:98.19%Color and Shape:SolidMolecular weight:431.89Ref: TM-T71740
1mg333.00€5mg922.00€10mg1,140.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,664.00€NAV-2729
CAS:NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.Formula:C25H17ClN4O3Purity:98.83% - 98.91%Color and Shape:SolidMolecular weight:456.88Ref: TM-T5142
2mg46.00€5mg66.00€10mg96.00€25mg205.00€50mg303.00€100mg454.00€500mg938.00€1mL*10mM (DMSO)74.00€CCG-63808
CAS:CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.Formula:C25H15FN4O2SPurity:90%Color and Shape:SolidMolecular weight:454.48RBC10
CAS:RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Formula:C24H25ClN2O2Purity:98.38%Color and Shape:SolidMolecular weight:408.92Ref: TM-T24706
1mg34.00€2mg52.00€5mg80.00€10mg116.00€25mg259.00€50mg374.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)86.00€IMM-01
CAS:IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actinFormula:C12H17N3O2SPurity:98.87%Color and Shape:SolidMolecular weight:267.35Ref: TM-T25529
1mg52.00€5mg97.00€10mg170.00€25mg369.00€50mg593.00€100mg893.00€200mg1,198.00€1mL*10mM (DMSO)97.00€ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139Ref: TM-T21970
5mg65.00€10mg95.00€25mg140.00€50mg202.00€100mg303.00€500mg725.00€1mL*10mM (DMSO)71.00€Compound C108
CAS:Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).Formula:C15H14N2O3Purity:99.77%Color and Shape:SolidMolecular weight:270.28Ref: TM-T38387
1mg46.00€5mg89.00€10mg130.00€25mg251.00€50mg401.00€100mg597.00€500mg1,283.00€1mL*10mM (DMSO)125.00€MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48Ref: TM-T7558
1mg35.00€2mg52.00€5mg74.00€10mg111.00€25mg188.00€50mg246.00€100mg319.00€1mL*10mM (DMSO)82.00€CCG-63802
CAS:CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Formula:C26H18N4O2SPurity:90%Color and Shape:SolidMolecular weight:450.51CCG-50014
CAS:CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.Formula:C16H13FN2O2SPurity:98.53%Color and Shape:SolidMolecular weight:316.35Anti-inflammatory agent 49
CAS:Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrialFormula:C21H22N8O3SPurity:99.62% - 99.74%Color and Shape:SolidMolecular weight:466.52QS11
CAS:QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.Formula:C36H33N5O2Purity:98.39%Color and Shape:SolidMolecular weight:567.68Ref: TM-T4022
2mg35.00€5mg52.00€10mg85.00€25mg156.00€50mg226.00€100mg340.00€200mg465.00€1mL*10mM (DMSO)65.00€Gancaonin I
CAS:Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.Formula:C21H22O5Purity:98%Color and Shape:SolidMolecular weight:354.4BQU57
CAS:BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formula:C16H13F3N4OPurity:97.45% - 98.72%Color and Shape:SolidMolecular weight:334.3Exo-1
CAS:Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, asFormula:C15H12FNO3Purity:99.45%Color and Shape:SolidMolecular weight:273.26Ref: TM-T9200
5mg55.00€10mg82.00€25mg126.00€50mg182.00€100mg273.00€200mg409.00€500mg677.00€1mL*10mM (DMSO)69.00€RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Ref: TM-T6634
1mg48.00€5mg92.00€10mg156.00€25mg298.00€50mg472.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€
