S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
Products of "S1P Receptor"
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Found 41 products on this category.
TY-52156
CAS:TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).Formula:C18H19Cl2N3OPurity:99.91%Color and Shape:SolidMolecular weight:364.27Ref: TM-T17183
2mg40.00€5mg60.00€10mg87.00€25mg166.00€50mg298.00€100mg510.00€200mg683.00€1mL*10mM (DMSO)66.00€N,N-Dimethylsphingosine
CAS:N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.Formula:C20H41NO2Purity:98%Color and Shape:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderMolecular weight:327.55S1p receptor agonist 1
CAS:S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.Formula:C23H24FN3O3Purity:99.07% - 99.90%Color and Shape:SolidMolecular weight:409.45Ozanimod
CAS:Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator.Formula:C23H24N4O3Purity:98.68% - 99.58%Color and Shape:SolidMolecular weight:404.46Ref: TM-T6923
1mg48.00€5mg96.00€10mg144.00€25mg283.00€50mg454.00€100mg655.00€200mg929.00€500mg1,378.00€1mL*10mM (DMSO)96.00€GSK2018682
CAS:GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).Formula:C22H21ClN4O4Purity:99.04%Color and Shape:SolidMolecular weight:440.88W140 HBr
CAS:[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.Formula:C16H28BrN2O4PPurity:99.34%Color and Shape:SoildMolecular weight:423.28Ref: TM-T60204
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€1mL*10mM (DMSO)284.00€SK1-IN-1
CAS:SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be used to study cancer and neurodegenerative diseases.Formula:C22H30N4O3Purity:98.72%Color and Shape:SolidMolecular weight:398.5BMS-960
CAS:BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.Formula:C26H23F3N4O5Purity:97.74% - 99.28%Color and Shape:SolidMolecular weight:528.48CYM-5541
CAS:CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.Formula:C19H28N2O2Purity:97.34% - 98.39%Color and Shape:SolidMolecular weight:316.44Ref: TM-T3961
2mg38.00€5mg57.00€10mg92.00€25mg160.00€50mg254.00€100mg373.00€500mg873.00€1mL*10mM (DMSO)64.00€ASP-4058
CAS:ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.Formula:C19H12F6N4O2Purity:99.5% - 99.51%Color and Shape:SolidMolecular weight:442.31Siponimod
CAS:Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; >1000x selectivity over S1P2-4.Formula:C29H35F3N2O3Purity:97.08% - 99.40%Color and Shape:SolidMolecular weight:516.59Cenerimod
CAS:Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma.Formula:C25H31N3O5Purity:97.43% - 99.97%Color and Shape:SolidMolecular weight:453.53SphK1&2-IN-1
CAS:SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.Formula:C14H14N2O3SPurity:99.27%Color and Shape:SolidMolecular weight:290.34GLPG2938
CAS:GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent andFormula:C20H19F6N7O2Purity:98.25%Color and Shape:SolidMolecular weight:503.4Ref: TM-T9199
1mg84.00€5mg153.00€10mg264.00€25mg550.00€50mg792.00€100mg1,093.00€200mg1,454.00€1mL*10mM (DMSO)166.00€Vibozilimod
CAS:Vibozilimod (SCD-044) is S1P receptor-1 (S1PR1) agonist .Formula:C29H36ClN3O5Purity:99.47%Color and Shape:SolidMolecular weight:542.07SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Formula:C25H34N4O7SPurity:100% - 99.57%Color and Shape:SolidMolecular weight:534.63MHP
CAS:MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.Formula:C16H23NO4Purity:98.58%Color and Shape:SolidMolecular weight:293.36Ref: TM-T4658
1mg47.00€2mg64.00€5mg111.00€10mg188.00€25mg376.00€50mg563.00€100mg800.00€1mL*10mM (DMSO)127.00€CS 2100
CAS:CS 2100 (1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid) is an S1P1 agonist.Formula:C25H23N3O4SPurity:98.13%Color and Shape:SolidMolecular weight:461.53VPC 23019
CAS:VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively).Formula:C17H29N2O5PPurity:98%Color and Shape:SolidMolecular weight:372.4AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formula:C26H22FN3O2SPurity:98.39% - 98.92%Color and Shape:SolidMolecular weight:459.54Amgen-23
CAS:Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.Formula:C23H25Cl2N3O2SPurity:97.31%Color and Shape:SolidMolecular weight:478.44Opaganib
CAS:Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).Formula:C23H25ClN2OPurity:98.86% - 99.85%Color and Shape:SolidMolecular weight:380.91Ref: TM-T6750
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg240.00€50mg415.00€100mg615.00€1mL*10mM (DMSO)87.00€Ponesimod
CAS:Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.Formula:C23H25ClN2O4SPurity:98.22% - 99.42%Color and Shape:SolidMolecular weight:460.97Ref: TM-T3258
1mg46.00€2mg59.00€5mg93.00€10mg131.00€25mg234.00€50mg404.00€100mg597.00€500mg1,283.00€1mL*10mM (DMSO)97.00€CYM-5520
CAS:CYM-5520 is a noncompetitive allosteric agonist of S1P2Formula:C21H19N3O2Purity:99.47%Color and Shape:SolidMolecular weight:345.39Ref: TM-T22703
1mg48.00€2mg64.00€5mg94.00€10mg142.00€25mg250.00€50mg374.00€100mg557.00€1mL*10mM (DMSO)103.00€PF429242 dihydrochloride
CAS:PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).Formula:C25H37Cl2N3O2Purity:98.67%Color and Shape:SolidMolecular weight:482.49MP-A08
CAS:MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.Formula:C27H25N3O4S2Purity:98.04%Color and Shape:SolidMolecular weight:519.64CYM5442
CAS:CYM5442 is an S1P agonist, targeting to Sphingosine.Formula:C23H27N3O4Purity:96.65% - 97.57%Color and Shape:SolidMolecular weight:409.48SLM6031434 HCl
CAS:SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.Formula:C22H31ClF3N5O2Purity:98%Color and Shape:SolidMolecular weight:489.96Etrasimod
CAS:Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).Formula:C26H26F3NO3Purity:99.17% - 99.77%Color and Shape:SolidMolecular weight:457.48Ref: TM-TQ0227
1mg52.00€5mg111.00€10mg180.00€25mg243.00€50mg305.00€100mg424.00€1mL*10mM (DMSO)113.00€K6PC-5
CAS:K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.Formula:C19H37NO4Purity:98.55%Color and Shape:SolidMolecular weight:343.5SK1-I hydrochloride
CAS:SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.Formula:C17H28ClNO2Purity:99.80%Color and Shape:SolidMolecular weight:313.86TASP 0277308
CAS:NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activating protein (fap) inhibitor.Formula:C23H28Cl2N6O3SColor and Shape:SolidMolecular weight:539.48LX-2931
CAS:LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.Formula:C9H15N3O5Purity:100% - 99.83%Color and Shape:SolidMolecular weight:245.23SEW2871
CAS:SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.Formula:C20H10F6N2OSPurity:99.62%Color and Shape:White SolidMolecular weight:440.36CYM50374
CAS:CYM50374 inhibits Sphingosine-1-phosphate receptor 4 (S1P4 ) with an IC50 of µM.Formula:C19H19NO3SPurity:98.4% - 98.49%Color and Shape:SolidMolecular weight:341.42Ref: TM-T27106
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€ML-031
CAS:ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.Formula:C19H20N2O3Purity:99.21%Color and Shape:SolidMolecular weight:324.374-Deoxypyridoxine hydrochloride
CAS:4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.Formula:C8H12ClNO2Purity:99.86%Color and Shape:White To Off White Crystalline PowderMolecular weight:189.64Amiselimod hydrochloride
CAS:Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.Formula:C19H31ClF3NO3Purity:99.55%Color and Shape:SolidMolecular weight:413.9Ref: TM-T10305
1mg38.00€2mg49.00€5mg80.00€10mg120.00€25mg215.00€50mg354.00€100mg512.00€200mg738.00€1mL*10mM (DMSO)88.00€Ozanimod hydrochloride
CAS:Ozanimod (RPC-1063) HCl is a selective S1P1/S1P5 modulator with high affinity, used in relapsing MS research.Formula:C23H25ClN4O3Purity:99.81%Color and Shape:SolidMolecular weight:440.92Ref: TM-T62552
1mg66.00€5mg139.00€10mg202.00€25mg416.00€50mg652.00€100mg938.00€500mg1,872.00€1mL*10mM (DMSO)154.00€CYM50308
CAS:CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).Formula:C20H21F2N3O2SPurity:99.43% - 99.63%Color and Shape:SolidMolecular weight:405.46Ref: TM-T15032
1mg62.00€5mg140.00€10mg202.00€25mg324.00€50mg455.00€100mg597.00€200mg842.00€500mg1,225.00€SLP9101555
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-foldFormula:C16H22BrClN2Purity:99%Color and Shape:SolidMolecular weight:357.72Ref: TM-T63047
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€1mL*10mM (DMSO)663.00€
