DHFR
Dihydrofolate reductase (DHFR) is an enzyme that plays a crucial role in the folate cycle, which is essential for DNA synthesis, repair, and methylation. DHFR inhibitors are widely used as chemotherapeutic agents in the treatment of cancer and autoimmune diseases due to their ability to inhibit cell proliferation. At CymitQuimica, we provide a variety of DHFR inhibitors to support your research in cancer therapy, immunology, and molecular biology.
Products of "DHFR"
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Found 29 products on this category.
Fanotaprim
CAS:Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.Formula:C19H22N8OPurity:97.37%Color and Shape:SolidMolecular weight:378.43Ref: TM-T36692
1mg52.00€2mg74.00€5mg116.00€10mg178.00€25mg335.00€50mg467.00€100mg662.00€200mg892.00€1mL*10mM (DMSO)128.00€Dihydrofolate reductase Protein, Human, Recombinant (His)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:25.5 kDa (predicted)Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Formula:C14H18N4O3Purity:99.80% - 99.81%Color and Shape:White To Yellowish PowderMolecular weight:290.32Lometrexol
CAS:Lometrexol (LY 264618) is an antifolate that inhibits GARFT, blocks purine synthesis, induces apoptosis, and has anticancer properties.Formula:C21H25N5O6Purity:98.57% - 99.35%Color and Shape:SolidMolecular weight:443.45Ref: TM-T15826
1mg88.00€5mg188.00€10mg311.00€25mg533.00€50mg787.00€100mg1,093.00€200mg1,454.00€1mL*10mM (DMSO)215.00€Pelitrexol
CAS:Pelitrexol (AG 2037) is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor.Formula:C20H25N5O6SPurity:98%Color and Shape:SolidMolecular weight:463.51Talotrexin ammonium
CAS:Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.Formula:C27H30N10O6Purity:97.49%Color and Shape:SolidMolecular weight:590.59Ref: TM-T64295
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€Epiroprim
CAS:Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor with antibacterial activity, inhibiting Staphylococcus and Streptococcus.Formula:C19H23N5O2Purity:100% - 99.68%Color and Shape:SolidMolecular weight:353.42Anti-Dihydrofolate reductase Antibody (2V859)
Anti-Dihydrofolate reductase Antibody (2V859) is an antibody targeting Dihydrofolate reductase. Anti-Dihydrofolate reductase Antibody (2V859) can be used in ELISA, WB, IHC, IP.Color and Shape:Odour Liquid10-Formylfolic acid
CAS:10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Formula:C20H19N7O7Purity:98.42%Color and Shape:SolidMolecular weight:469.41WR99210
CAS:WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.Formula:C14H18Cl3N5O2Purity:98.8%Color and Shape:SolidMolecular weight:394.68(Rac)-Managlinat dialanetil
CAS:Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.Formula:C21H33N4O6PSPurity:98.52%Color and Shape:SolidMolecular weight:500.554′-DTMP
CAS:4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.Formula:C13H16N4O3Purity:98%Color and Shape:SolidMolecular weight:276.29LY 222306
CAS:LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.Formula:C19H23N5O7Purity:98%Color and Shape:SolidMolecular weight:433.42Diaveridine
CAS:Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide.Formula:C13H16N4O2Purity:99.10%Color and Shape:White SolidMolecular weight:260.29DHFR-IN-4
CAS:DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Formula:C18H21N5O2SPurity:99.41%Color and Shape:SolidMolecular weight:371.46Sulfadoxine
CAS:Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarialFormula:C12H14N4O4SPurity:99.67%Color and Shape:White Or White Crystalline PowderMolecular weight:310.33DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Formula:C8H7BrN4Purity:99.59% - 99.61%Color and Shape:SolidMolecular weight:239.07Piritrexim
CAS:Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used in the study of uroepithelial carcinomaFormula:C17H19N5O2Purity:99.13% - 99.68%Color and Shape:SolidMolecular weight:325.37LY 345899
CAS:LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM forFormula:C20H21N7O7Purity:99.69%Color and Shape:SolidMolecular weight:471.42Ref: TM-T15827
1mg48.00€5mg160.00€10mg235.00€25mg426.00€50mg623.00€100mg905.00€500mg1,786.00€1mL*10mM (DMSO)165.00€Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:22.0 kDa (predicted)P 218
CAS:P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.Formula:C18H25ClN4O4Purity:99.50%Color and Shape:SoildMolecular weight:396.87Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:25.6 kDa (predicted)DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purity:99.13%Color and Shape:SolidMolecular weight:349.34Ref: TM-T37655
1mg78.00€5mg169.00€10mg250.00€25mg432.00€50mg628.00€100mg905.00€1mL*10mM (DMSO)178.00€Methotrexate Diglutamate
CAS:Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified human dihydrofolate reductase inhibitor.Formula:C25H29N9O8Purity:98.84%Color and Shape:SolidMolecular weight:583.55Brodimoprim
CAS:Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).Formula:C13H15BrN4O2Purity:98% - 98.33%Color and Shape:SolidMolecular weight:339.19Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Formula:C12H13ClN4Purity:99.67%Color and Shape:CrystalsMolecular weight:248.71Sulfameter
CAS:Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.Formula:C11H12N4O3SPurity:99.46% - 99.90%Color and Shape:Crystalline SolidMolecular weight:280.3Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formula:C20H21N5O6Purity:98.1% - 99.92%Color and Shape:Similar To White PowderMolecular weight:427.41DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Formula:C28H31F3N4O6SPurity:98.27% - 99.63%Color and Shape:SolidMolecular weight:608.63Ref: TM-T11103
1mg115.00€5mg274.00€10mg432.00€25mg777.00€50mg1,264.00€100mg1,700.00€1mL*10mM (DMSO)378.00€
