DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Products of "DNA/RNA Synthesis"
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TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Formula:C13H12Cl2N4Purity:96.05% - 99.82%Color and Shape:SolidMolecular weight:295.17Werner syndrome RecQ helicase-IN-1
CAS:Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomachFormula:C31H31ClF3N9O5Purity:98.74% - 99.62%Color and Shape:SolidMolecular weight:702.08Ref: TM-T72107
1mg60.00€5mg125.00€10mg177.00€25mg296.00€50mg502.00€100mg803.00€500mg1,795.00€1mL*10mM (DMSO)822.00€NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formula:C23H19N3O4SPurity:98.03% - 99.46%Color and Shape:SolidMolecular weight:433.48Ref: TM-T8886
1mg74.00€5mg170.00€10mg274.00€25mg472.00€50mg655.00€100mg944.00€200mg1,264.00€1mL*10mM (DMSO)188.00€RG7800
CAS:RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.Formula:C24H28N6OPurity:99.44%Color and Shape:SolidMolecular weight:416.52ART558
CAS:ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).Formula:C21H21F3N4O2Purity:99.18%Color and Shape:SolidMolecular weight:418.41T4 RNA ligase
T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA.Purity:98%Color and Shape:Odour SolidAT-130
CAS:AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.Formula:C22H22BrN3O5Purity:97.81%Color and Shape:SolidMolecular weight:488.33Ref: TM-T26674
1mg42.00€5mg90.00€10mg131.00€25mg226.00€50mg339.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)87.00€Methotrexate
CAS:Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Formula:C20H22N8O5Purity:96.84% - 99.46%Color and Shape:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisMolecular weight:454.44DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurity:97.8% - 99.76%Color and Shape:SolidMolecular weight:495.43Ref: TM-T27135
1mg96.00€5mg279.00€10mg420.00€25mg682.00€50mg947.00€100mg1,301.00€200mg1,738.00€1mL*10mM (DMSO)305.00€Quinizarin
CAS:Quinizarin (1,4-Dihydroxyanthraquinone) is a natural productFormula:C14H8O4Purity:97.02%Color and Shape:Leaves Yellow Red And Needles Dark Red Solid Leaves Or NeedlesMolecular weight:240.21Enrofloxacin
CAS:Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.Formula:C19H22FN3O3Purity:100% - 99.89%Color and Shape:Pale Yellow CrystalsMolecular weight:359.39TK216
CAS:TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Formula:C19H15Cl2NO3Purity:97.22%Color and Shape:SolidMolecular weight:376.23DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purity:98.87% - 99.53%Color and Shape:SolidMolecular weight:360.41SCR7
CAS:SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).Formula:C18H14N4OSPurity:98%Color and Shape:SolidMolecular weight:334.4GS-9191
CAS:GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , whichFormula:C37H51N8O6PPurity:98.01% - 98.28%Color and Shape:SolidMolecular weight:734.82NRTT-IN-1
CAS:NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.Formula:C28H24FN5O5Color and Shape:SolidMolecular weight:529.519Taq DNA polymerase
CAS:Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].Purity:98%Color and Shape:SolidO6-Benzylguanine
CAS:O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.Formula:C12H11N5OPurity:98.90%Color and Shape:Solid CrystallineMolecular weight:241.25DHX9-IN-2
CAS:DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.Formula:C18H16ClN3O3S2Purity:98.00%Color and Shape:SolidMolecular weight:421.92NKP-1339
CAS:NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formula:C14H12Cl4N4NaRuPurity:98%Color and Shape:SolidMolecular weight:502.14MTH1 ligand 1
CAS:MTH1 ligand 1 functions as a target protein ligand for MTH1, and is utilized in the synthesis of PROTACaTAG 2139.Formula:C23H18N4O3Color and Shape:SolidMolecular weight:398.41Levofloxacin
CAS:Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.Formula:C18H20FN3O4Purity:98.14% - 99.80%Color and Shape:Off-White To Yellow CrystalsMolecular weight:361.37Nolatrexed dihydrochloride
CAS:Nolatrexed dihydrochloride (Thymitaq) is a soluble, lipophilic cancer drug that inhibits DNA replication, causing cell cycle arrest and apoptosis.Formula:C14H14Cl2N4OSPurity:97.02%Color and Shape:Tan SolidMolecular weight:357.26Anisomycin
CAS:Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.Formula:C14H19NO4Purity:98.33% - 99.81%Color and Shape:White Crystalline SolidMolecular weight:265.3DI-87
CAS:DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Formula:C23H30N6O3S2Purity:99.76%Color and Shape:SolidMolecular weight:502.65Phleomycin
CAS:Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage.Formula:C48H69N17O20S2Purity:98%Color and Shape:SolidMolecular weight:1268.29Mithramycin A
CAS:Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of variousFormula:C52H76O24Purity:99.28%Color and Shape:Yellow PowderMolecular weight:1085.15WRN inhibitor 1
CAS:WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.Formula:C16H13FN2O4SPurity:98%Color and Shape:SolidMolecular weight:348.35Dithranol
CAS:Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especiallyFormula:C14H10O3Purity:93.49% - ≥98%Color and Shape:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingMolecular weight:226.23Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Ref: TM-T4226
1mg60.00€2mg79.00€5mg124.00€10mg197.00€25mg325.00€50mg505.00€100mg730.00€500mg1,501.00€1mL*10mM (DMSO)140.00€BWC0977
CAS:BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.Formula:C22H21FN6O5Color and Shape:SolidMolecular weight:468.44GSK_WRN4
CAS:GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer researchFormula:C16H20N2O4SPurity:100%Color and Shape:SolidMolecular weight:336.41Brr2-IN-2
Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.Formula:C21H25FN4O2Color and Shape:SolidMolecular weight:384.45Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purity:96.68% - 98.13%Color and Shape:SolidMolecular weight:320.25IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purity:98.26% - 99.64%Color and Shape:SolidMolecular weight:473.88Ref: TM-T8842
1mg145.00€5mg311.00€10mg533.00€25mg775.00€50mg938.00€100mg1,320.00€1mL*10mM (DMSO)325.00€CeMMEC1
CAS:CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).Formula:C19H16N2O4Purity:100% - 99.26%Color and Shape:SolidMolecular weight:336.34Sorivudine
CAS:Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.Formula:C11H13BrN2O6Purity:97.33%Color and Shape:SolidMolecular weight:349.13Adenine hemisulfate
CAS:Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistryFormula:(C5H5N5)·H2SO4Purity:99.78%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:368.336-Hydroxy-DOPA
CAS:6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.Formula:C9H11NO5Purity:96.59% - 97.23%Color and Shape:SolidMolecular weight:213.19AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Formula:C17H19F3N4O3SPurity:99.96%Color and Shape:SolidMolecular weight:416.42WRN inhibitor 16
WRN inhibitor 16 (Example 83) is an orally active WRN inhibitor. In a SW48 xenograft mouse tumor model, WRN inhibitor 16 did not cause tumor regression.Formula:C31H30F4N4O5SColor and Shape:SolidMolecular weight:646.65Floxuridine
CAS:Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formula:C9H11FN2O5Purity:98.92% - 99.96%Color and Shape:SolidMolecular weight:246.19Lomibuvir
CAS:Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.Formula:C25H35NO4SPurity:100%Color and Shape:SolidMolecular weight:445.61Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purity:98.4% - 99.54%Color and Shape:SolidMolecular weight:956.68Ref: TM-TQ0184
1mg73.00€5mg155.00€10mg219.00€25mg465.00€50mg692.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)266.00€Folic acid
CAS:Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.Formula:C19H19N7O6Purity:99.19% - 99.27%Color and Shape:Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FMolecular weight:441.4N-Nitrosodiethylamine
CAS:N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine.Formula:C4H10N2OPurity:99.26% - ≥98%Color and Shape:SolidMolecular weight:102.14Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05360A
CAS:360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5Fludarabine
CAS:Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formula:C10H12FN5O4Purity:100% - 99.88%Color and Shape:White SolidMolecular weight:285.23MM41
CAS:MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.Formula:C44H66N10O6Purity:97.13%Color and Shape:SolidMolecular weight:831.06Ref: TM-T60028
1mg52.00€5mg116.00€10mg178.00€25mg293.00€50mg393.00€100mg520.00€200mg712.00€1mL*10mM (DMSO)160.00€(S)-crizotinib
CAS:(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.Formula:C21H22Cl2FN5OPurity:98.52% - 99.47%Color and Shape:SolidMolecular weight:450.34Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Formula:C7H7NO4Purity:96.85%Color and Shape:SolidMolecular weight:169.13DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formula:C14H11F3N2O2Purity:99.74%Color and Shape:SolidMolecular weight:296.24Ref: TM-T12438
1mg50.00€5mg106.00€10mg160.00€25mg311.00€50mg472.00€100mg695.00€200mg938.00€1mL*10mM (DMSO)97.00€Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formula:C14H12N4OSPurity:97.91%Color and Shape:SolidMolecular weight:284.34Ref: TM-T4228
1mg42.00€2mg50.00€5mg90.00€10mg148.00€25mg240.00€50mg430.00€100mg633.00€1mL*10mM (DMSO)96.00€Fialuridine
CAS:Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Formula:C9H10FIN2O5Purity:99.71% - 99.90%Color and Shape:Less Crystals Colourless CrystalsMolecular weight:372.09Ref: TM-T7655
1mg35.00€5mg74.00€10mg116.00€25mg235.00€50mg373.00€100mg562.00€500mg1,216.00€1mL*10mM (DMSO)82.00€Enoxacin
CAS:Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formula:C15H17FN4O3Purity:98.68% - 99.89%Color and Shape:Off-White To Yellow CrystalsMolecular weight:320.32POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂,IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。Formula:C21H20N6Purity:98%Color and Shape:SolidMolecular weight:356.42Foscarnet sodium
CAS:Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.Formula:CNa3O5PPurity:98.52%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:191.95IDD388
CAS:IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formula:C16H12BrClFNO4Purity:99.56%Color and Shape:SolidMolecular weight:416.63RdRP-IN-6
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM.Formula:C41H67N8O7PSi2Purity:98%Color and Shape:SolidMolecular weight:871.162,5-Di-tert-butyl-1,4-benzoquinone
CAS:2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formula:C14H20O2Color and Shape:SolidMolecular weight:220.31Neobavaisoflavone
CAS:Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.Formula:C20H18O4Purity:100% - 99.51%Color and Shape:SolidMolecular weight:322.35Ref: TM-T6S0139
5mg48.00€10mg70.00€25mg104.00€50mg153.00€100mg216.00€500mg540.00€1mL*10mM (DMSO)52.00€Bleomycin hydrochloride
CAS:Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.Formula:C55H84ClN17O21S3Purity:98%Color and Shape:SoildMolecular weight:1451.01(Average)Urolithin A
CAS:Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formula:C13H8O4Purity:99.14% - 99.66%Color and Shape:SolidMolecular weight:228.2Ref: TM-T7174
5mg49.00€10mg72.00€25mg130.00€50mg187.00€100mg320.00€200mg472.00€500mg753.00€1mL*10mM (DMSO)50.00€DNA gyrase B-IN-3
CAS:DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against GramFormula:C14H9Cl2N3O4SPurity:98%Color and Shape:SolidMolecular weight:386.21Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Formula:C22H22FN5O7Purity:99.51% - 99.82%Color and Shape:SolidMolecular weight:487.44Ref: TM-TQ0063
1mg111.00€5mg259.00€10mg410.00€25mg680.00€50mg938.00€100mg1,301.00€500mg2,593.00€1mL*10mM (DMSO)279.00€HALOFUGINONE LACTATE
CAS:HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Formula:C19H23BrClN3O6Purity:99.02% - 99.96%Color and Shape:SolidMolecular weight:504.8Ref: TM-T8785
2mg42.00€5mg59.00€10mg94.00€25mg130.00€50mg207.00€100mg309.00€200mg462.00€1mL*10mM (DMSO)66.00€Levofloxacin hydrochloride
CAS:Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H21ClFN3O4Purity:99.78% - 99.98%Color and Shape:SolidMolecular weight:397.8RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:373.83GS-443902
CAS:Remdesivir triphosphate (GS-443902) inhibits RSV/HCV RdRp with IC50s: 1.1/5 µM.Formula:C12H16N5O13P3Purity:98%Color and Shape:SolidMolecular weight:531.2hDHODH-IN-1
CAS:hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.Formula:C17H14N2O2Purity:99.75%Color and Shape:SolidMolecular weight:278.31Ref: TM-T11546
1mg48.00€5mg97.00€10mg156.00€25mg301.00€50mg439.00€100mg610.00€200mg822.00€1mL*10mM (DMSO)105.00€SCR130
CAS:SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂,可诱导细胞凋亡并,具有抗癌活性。 它特异性依赖连接酶 IV,抑制 DNA 的末端连接。Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormula:C13H10Cl4N2O4Purity:98.31% - 99.72%Color and Shape:SolidMolecular weight:400.04Ref: TM-T9168
1mg37.00€2mg52.00€5mg77.00€10mg96.00€25mg167.00€50mg240.00€100mg378.00€500mg889.00€1mL*10mM (DMSO)85.00€WRN inhibitor 15
WRN inhibitor 15 (Compound 9) is a WRN inhibitor with antitumor properties, displaying IC50 values of 37.9, 40.2, and 46.6 μM in PC3, LNCaP, and HeLa cells, respectively, making it suitable for prostate cancer research.Formula:C16H13F2N3OColor and Shape:SolidMolecular weight:301.29Synucleozid hydrochloride
CAS:Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Formula:C22H21ClN6Purity:98.13%Color and Shape:SolidMolecular weight:404.9KWR095
CAS:KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105PCNA-I1
CAS:PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.Formula:C17H14N2O2SPurity:97.64%Color and Shape:SolidMolecular weight:310.37YK-4-279
CAS:YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.Formula:C17H13Cl2NO4Purity:99.80% - ≥95%Color and Shape:SolidMolecular weight:366.2L-Methioninamide hydrochloride
CAS:L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.Formula:C5H13ClN2OSPurity:99.75%Color and Shape:SolidMolecular weight:184.692'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formula:C13H19N5O5Purity:99.35%Color and Shape:SolidMolecular weight:325.32Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFormula:C25H23FN4OPurity:98.38%Color and Shape:SolidMolecular weight:414.47Ref: TM-T8873
1mg49.00€5mg104.00€10mg166.00€25mg325.00€50mg490.00€100mg737.00€500mg1,483.00€1mL*10mM (DMSO)115.00€Werner syndrome RecQ helicase-IN-4
CAS:Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.Formula:C32H33F3N8O5Purity:98.27%Color and Shape:SolidMolecular weight:666.65CeMMEC13
CAS:CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).Formula:C19H16N2O4Purity:97.95%Color and Shape:SolidMolecular weight:336.34RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formula:C14H11Cl3N2O3Purity:99.3% - 99.62%Color and Shape:SolidMolecular weight:361.61BRD32048
CAS:BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.Formula:C16H22N6OPurity:99.69%Color and Shape:SolidMolecular weight:314.39Ref: TM-T23820
2mg52.00€5mg111.00€10mg175.00€25mg321.00€50mg512.00€100mg825.00€200mg1,111.00€1mL*10mM (DMSO)47.00€UNC9512
UNC9512 is a potent antagonist of the methyl-lysine reader protein 53BP1, which can be utilized to investigate the function of 53BP1 in DNA repair, gene editingFormula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64ZYN57939
CAS:ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.Formula:C28H27N7O2SPurity:99.68%Color and Shape:SolidMolecular weight:525.625-methoxyflavone
CAS:5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound.Formula:C16H12O3Purity:99.76%Color and Shape:PowderMolecular weight:252.26Ac-rC Phosphoramidite
CAS:Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.Formula:C47H64N5O9PSiPurity:99.49%Color and Shape:SolidMolecular weight:902.1Sodium Camptothecin
CAS:Sodium Camptothecin: plant-derived, antitumor, inhibits RNA/DNA synthesis, disrupts viral DNA.Formula:C20H18N2NaO5Purity:98.71%Color and Shape:SolidMolecular weight:389.36Uridine-5'-diphosphate disodium salt
CAS:UDP disodium salt is a P2Y6 agonist (EC50 = 13 nM), enhances inflammation, phagocytosis, vasoconstriction, and inhibits P2Y14.Formula:C9H12N2Na2O12P2Purity:100% - 98.86%Color and Shape:White Fine CrystalsMolecular weight:448.12Triciribine
CAS:Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Formula:C13H16N6O4Purity:99.01% - 99.87%Color and Shape:SolidMolecular weight:320.3Ref: TM-T6065
1mg43.00€2mg57.00€5mg93.00€10mg135.00€25mg236.00€50mg394.00€100mg588.00€1mL*10mM (DMSO)93.00€AVN-944
CAS:AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.Formula:C25H27N5O5Purity:99.07% - ≥95%Color and Shape:SolidMolecular weight:477.51WRN inhibitor 2
CAS:WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].Formula:C15H11F3N2O5S2Purity:98%Color and Shape:SolidMolecular weight:420.38DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formula:C44H54N7O8PPurity:99.74%Color and Shape:SolidMolecular weight:839.92AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formula:C30H22F6N6O5Purity:97.14%Color and Shape:SolidMolecular weight:660.52Ref: TM-T6753
2mg40.00€5mg60.00€10mg96.00€25mg169.00€50mg245.00€100mg361.00€200mg512.00€1mL*10mM (DMSO)88.00€SR15006
CAS:SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Formula:C16H20ClN3O4SPurity:99.78%Color and Shape:SoildMolecular weight:385.87Ref: TM-T60037
5mg39.00€10mg64.00€25mg117.00€50mg212.00€100mg316.00€200mg454.00€1mL*10mM (DMSO)62.00€Eriodictyol
CAS:Eriodictyol: anti-inflammatory, antioxidant, may improve diabetes and atopic dermatitis symptoms.Formula:C15H12O6Purity:98.03% - 98.93%Color and Shape:SolidMolecular weight:288.25
