DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Products of "DNA/RNA Synthesis"
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NCGC00029283
CAS:NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 μMFormula:C18H12FN3O3Purity:99.6%Color and Shape:SolidMolecular weight:337.3Ref: TM-T40823
1mg111.00€2mg163.00€5mg264.00€10mg432.00€25mg747.00€50mg1,103.00€100mg1,539.00€1mL*10mM (DMSO)283.00€Votoplam
CAS:Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].Formula:C21H25N9OPurity:98%Color and Shape:SolidMolecular weight:419.48APE1-IN-3
CAS:APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.Formula:C17H16O4Color and Shape:SolidMolecular weight:284.31Dehydroaltenusin
CAS:Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM).Formula:C15H12O6Purity:98%Color and Shape:SolidMolecular weight:288.255Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formula:C41H44N4O10SPurity:98.11%Color and Shape:SolidMolecular weight:784.87Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H20FN3O4H2OPurity:98.26%Color and Shape:Pale Yellow SolidMolecular weight:370.38Clofarabine-5'-triphosphate
CAS:Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.Formula:C10H14ClFN5O12P3Color and Shape:SolidMolecular weight:543.62Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47Ref: TM-T4060
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg274.00€50mg487.00€100mg708.00€1mL*10mM (DMSO)97.00€Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48TH287
CAS:TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Formula:C11H10Cl2N4Purity:97.73% - 99%Color and Shape:SolidMolecular weight:269.13Ref: TM-T2069
1mg37.00€2mg48.00€5mg72.00€10mg96.00€25mg188.00€50mg366.00€100mg545.00€1mL*10mM (DMSO)79.00€WRN inhibitor 17
CAS:WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.Formula:C33H34F4N4O6SColor and Shape:SolidMolecular weight:690.71Moloney murine leukemia virus RT
Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to the retrovirus life cycle [1].Purity:98%Color and Shape:Odour SolidIMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Formula:C25H29F2N5OPurity:98.26% - 99.08%Color and Shape:SolidMolecular weight:453.53Ref: TM-T9350
1mg144.00€2mg188.00€5mg283.00€10mg469.00€25mg833.00€50mg1,121.00€1mL*10mM (DMSO)310.00€Gemcitabine
CAS:Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4Purity:100% - 99.67%Color and Shape:SolidMolecular weight:263.26-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31Folinic acid calcium
CAS:Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.Formula:C20H21CaN7O7Purity:100% - 99.5%Color and Shape:Yellow Crystalline PowderMolecular weight:511.5115(S)-HpETE
CAS:15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47Pseudouridine
CAS:Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.Formula:C9H12N2O6Purity:99.30%Color and Shape:SolidMolecular weight:244.2Famciclovir
CAS:Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Formula:C14H19N5O4Purity:99.85%Color and Shape:Off-White PowderMolecular weight:321.33Emzadirib
CAS:Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.Formula:C27H40N4O6S2Purity:99.79%Color and Shape:SolidMolecular weight:580.76SMN-C3
CAS:SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).Formula:C24H28N6OPurity:98.21% - 99.31%Color and Shape:SolidMolecular weight:416.52DNA Gyrase-IN-12
DNA Gyrase-IN-12 (Compound 6d) is an inhibitor of DNA gyrase. It exhibits antibacterial activity with MIC values ranging from 0.031 to 0.0625 μg/mL against Vancomycin-Intermediate Staphylococcus aureus (VISA) and Enterococcus faecium.Color and Shape:Odour SolidMethylproamine
CAS:Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.Formula:C28H31N7Purity:98.73%Color and Shape:SolidMolecular weight:465.59L-Asparaginase
CAS:L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.Formula:NAPurity:97%Color and Shape:SolidMolecular weight:N/ADencatistat
CAS:Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.Formula:C24H27N7O5SPurity:98.85%Color and Shape:SolidMolecular weight:525.58dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormula:C10H16N5O13P3Purity:99.9%Color and Shape:SolidMolecular weight:507.18Guanine
CAS:Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids.Formula:C5H5N5OPurity:99.89%Color and Shape:Several Desmotropic Forms; Usually Amorphous SolidMolecular weight:151.13HNC-1664
CAS:HNC-1664 is an orally active inhibitor of RNA-dependent RNA polymerase (RdRP). It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 wild type and its variants (XBB.1.18, HK.3.1, BF.7.14, BA.1, HCoV-229E, HCoV-OC43), as well as arenaviruses. HNC-1664 also demonstrates anti-infective efficacy in a mouse model infected with the SARS-CoV-2 Delta variant.Formula:C12H13FIN3O3Color and Shape:SolidMolecular weight:393.153ddTTP trisodium
Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNAFormula:C10H14N2Na3O13P3Purity:98%Color and Shape:SolidMolecular weight:532.11Danofloxacin mesylate
CAS:Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.Formula:C19H20FN3O3·CH4O3SPurity:99.73%Color and Shape:Crystalline SolidMolecular weight:453.48Gentisin
CAS:Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.Formula:C14H10O5Purity:95.34%Color and Shape:SolidMolecular weight:258.23DNA Gyrase-IN-13
CAS:DNA Gyrase-IN-13 (compound 1b) is an inhibitor of DNA gyrase with bacteriostatic properties. It exhibits an IC50 of 1.81 μM against Staphylococcus aureus DNA gyrase.Formula:C15H21N3O3SColor and Shape:SolidMolecular weight:323.41Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Formula:C35H33FN6O3Purity:99.77%Color and Shape:SolidMolecular weight:604.67Ref: TM-T16703
1mg119.00€5mg169.00€10mg264.00€25mg487.00€50mg652.00€100mg847.00€1mL*10mM (DMSO)234.00€qsl-304
QSL-304 is a DNA gyrase B inhibitor that serves as an antibacterial agent, exhibiting an IC50 of 31.23 mg/mL against Staphylococcus aureus SA-P2003 [1].Formula:C11H9NO4S2Purity:98%Color and Shape:SolidMolecular weight:283.32Procaine hydrochloride
CAS:Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.Formula:C13H20N2O2·HClPurity:100.00% - 99.22%Color and Shape:White Crystalline PowderMolecular weight:272.77Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71Methotrexate disodium
CAS:Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitorFormula:C20H20N8Na2O5Purity:99.77% - 99.96%Color and Shape:SolidMolecular weight:498.4Garenoxacin
CAS:Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.Formula:C23H20F2N2O4Purity:98%Color and Shape:SolidMolecular weight:426.41DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Formula:C15H11N3O2Purity:98.14%Color and Shape:SolidMolecular weight:265.27Tempo
CAS:Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as aFormula:C9H18NOPurity:98.35%Color and Shape:Orange Crystals Or PowderMolecular weight:156.25TH287 hydrochloride
CAS:TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.Formula:C11H11Cl3N4Purity:99.5%Color and Shape:SolidMolecular weight:305.59RNA polymerase II-IN-1
CAS:RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.Formula:C38H53N11O12SPurity:98%Color and Shape:SolidMolecular weight:887.96ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.32Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formula:C11H16ClN5Purity:99.6%Color and Shape:SolidMolecular weight:253.73BI8622
CAS:BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.Formula:C25H26N6OPurity:98.28%Color and Shape:SolidMolecular weight:426.51Butylparaben sodium
CAS:Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1Formula:C11H13NaO3Purity:98%Color and Shape:SolidMolecular weight:216.21Lucanthone
CAS:Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formula:C20H24N2OSPurity:99.92%Color and Shape:Yellow Crystals From Alcohol SolidMolecular weight:340.48Ref: TM-T4569
1mg56.00€2mg80.00€5mg126.00€10mg188.00€25mg400.00€50mg592.00€100mg837.00€1mL*10mM (DMSO)140.00€COH1
CAS:COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].Formula:C11H10N2O3SPurity:98%Color and Shape:SolidMolecular weight:250.27Madrasin
CAS:Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Formula:C16H17N5O2Purity:99.44% - 99.61%Color and Shape:SolidMolecular weight:311.34ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Formula:C17H21ClN2O4SPurity:99.33% - 99.45%Color and Shape:SolidMolecular weight:384.882-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Formula:C5H4FN5Purity:99.49%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:153.123,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:97.28%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.06GS-441524
CAS:GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.Formula:C12H13N5O4Purity:98.78% - 99.75%Color and Shape:SolidMolecular weight:291.26IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:351.4Ref: TM-T8841
1mg81.00€5mg170.00€10mg301.00€25mg563.00€50mg805.00€100mg1,111.00€1mL*10mM (DMSO)188.00€PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:SolidMolecular weight:453.9Ref: TM-T84770
1mg92.00€5mg188.00€10mg313.00€25mg603.00€50mg840.00€100mg1,169.00€200mg1,586.00€1mL*10mM (DMSO)216.00€DMT-dU-CE Phosphoramidite
CAS:DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.Formula:C39H47N4O8PPurity:97.58%Color and Shape:SolidMolecular weight:730.79Antiviral agent 36
Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100Formula:C30H32N4O3Purity:98%Color and Shape:SolidMolecular weight:496.6Votoplam HCl
CAS:Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).Formula:C21H26ClN9OPurity:99.49%Color and Shape:SoildMolecular weight:455.94Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurity:99.54% - 99.62%Color and Shape:SolidMolecular weight:493.57Rifalazil
CAS:Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.Formula:C51H64N4O13Purity:98%Color and Shape:SolidMolecular weight:941.073-Isomangostin
CAS:3-Isomangostin inhibits acetylcholinesterase, aldose reductase (IC50 = 3.48 uM), MTH1 (IC50 = 52 nM), and exhibits antiplasmodial activity.Formula:C24H26O6Purity:99.76%Color and Shape:SolidMolecular weight:410.46D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Formula:C23H36N6SPurity:99.04%Color and Shape:SolidMolecular weight:428.64Ref: TM-T10936
1mg37.00€2mg52.00€5mg77.00€10mg126.00€25mg283.00€50mg390.00€100mg567.00€1mL*10mM (DMSO)85.00€Rifapentine
CAS:Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.Formula:C47H64N4O12Purity:95.74% - ≥98%Color and Shape:SolidMolecular weight:877.03Capecitabine
CAS:Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.Formula:C15H22FN3O6Purity:100% - 99.89%Color and Shape:Less Solid Colourless SolidMolecular weight:359.35APE1-IN-1
CAS:APE1-IN-1 is a purine/pyrimidine-free endonuclease 1 inhibitor with potential antitumor activity that enhances the toxicity of alkylating agents on cancer cellsFormula:C19H21N3OS2Purity:98.50%Color and Shape:SolidMolecular weight:371.52SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formula:C18H12N4OSPurity:98.72% - 99.85%Color and Shape:SolidMolecular weight:332.38Ref: TM-T1724
1mg39.00€2mg50.00€5mg79.00€10mg120.00€25mg258.00€50mg408.00€100mg588.00€1mL*10mM (DMSO)79.00€DHODH-IN-16
CAS:DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).Formula:C24H25FN4O3Purity:99.64%Color and Shape:SolidMolecular weight:436.48WRN inhibitor 18
CAS:WRN inhibitor 18 (compound 306) is an orally active inhibitor of WRN with demonstrated anticancer activity in vivo.Formula:C35H35F6N5O5SColor and Shape:SolidMolecular weight:751.743-Hydroxy-2-methylpyridine
CAS:3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.Formula:C6H7NOPurity:98.96% - 99.03%Color and Shape:Beige-Brown PowderMolecular weight:109.13TMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Formula:C72H66N8O12S4Purity:99.11% - 99.85%Color and Shape:SolidMolecular weight:1363.6Tubercidin
CAS:Tubercidin, an adenosine analogue nucleoside antibiotic, hinders DNA/RNA synthesis and possesses antifungal and antiviral properties.Formula:C11H14N4O4Purity:100% - 99.38%Color and Shape:SolidMolecular weight:266.25GSK4418959
CAS:GSK4418959 (IDE275) is an oral, non-covalent, reversible, and selective WRN helicase inhibitor.inhibits ATPase and DNA unwinding functions. MSI-H.Formula:C31H30F4N4O5SColor and Shape:SoildMolecular weight:646.65AVG-233
CAS:AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.Formula:C26H22ClN5O3Purity:99%Color and Shape:SolidMolecular weight:487.94GW8510
CAS:GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.Formula:C21H15N5O3S2Purity:99.32%Color and Shape:SolidMolecular weight:449.51Ref: TM-T24125
1mg52.00€5mg97.00€10mg169.00€25mg329.00€50mg537.00€100mg868.00€200mg1,169.00€1mL*10mM (DMSO)111.00€Docosanoic acid
CAS:Docosanoic acid (Behenic Acid) is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.Formula:C22H44O2Purity:100%Color and Shape:Waxy Solid Liquid Othersolid PelletslargecrystalsMolecular weight:340.58CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formula:C9H6N2O4Purity:98.27% - 98.98%Color and Shape:Brown PowderMolecular weight:206.15Clofarabine-5'-diphosphate
CAS:Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.Formula:C10H13ClFN5O9P2Color and Shape:SolidMolecular weight:463.64Datelliptium chloride
CAS:Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.Formula:C23H28ClN3OPurity:98%Color and Shape:SolidMolecular weight:397.94Alovudine
CAS:3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.Formula:C10H13FN2O4Purity:99.41%Color and Shape:Less Solid Colourless SolidMolecular weight:244.22PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFormula:C25H20Cl2N2O3Purity:99.19%Color and Shape:SolidMolecular weight:467.34Ref: TM-T12574
1mg117.00€5mg243.00€10mg369.00€25mg622.00€50mg885.00€100mg1,206.00€1mL*10mM (DMSO)250.00€2,4-D
CAS:2,4-D (Hedonal) is a synthetic auxin regulating plant growth and an herbicide disrupting root elongation.Formula:C8H6Cl2O3Purity:99.42%Color and Shape:White To Yellow Crystalline Powder /Srp Yellow Color Is Phenolic Impurities/ Is Threat To The Environment Immediate Steps Should Be Taken To Limit Spread To The EnvironmentMolecular weight:221.04Procaine
CAS:Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.Formula:C13H20N2O2Purity:99.57% - 99.73%Color and Shape:Anhydrous Plates Tables From Ligroin Or Ether SolidMolecular weight:236.31T4 UvsX Recombinase
T4 UvsX Recombinase initiates DNA replication on double-stranded templates by catalyzing synapsis with a homologous primer single strand.Purity:98%Color and Shape:Odour SolidRI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purity:98.85% - 99.86%Color and Shape:SolidMolecular weight:433.28Ref: TM-T2628
1mg73.00€2mg97.00€5mg160.00€10mg281.00€25mg435.00€50mg640.00€100mg910.00€1mL*10mM (DMSO)170.00€Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Formula:C16H17BrClN3O3·HBrPurity:97.01% - 98.5%Color and Shape:SolidMolecular weight:495.59Ref: TM-T3524
1mg37.00€2mg52.00€5mg79.00€10mg112.00€25mg219.00€50mg328.00€100mg495.00€500mg947.00€1mL*10mM (DMSO)88.00€Deoxythymidine-5'-triphosphate trisodium
CAS:dTTP trisodium salt, a natural deoxynucleotide for DNA synthesis by DNA polymerase and reverse transcriptase.Formula:C10H14N2Na3O14P3Purity:99.77%Color and Shape:SolidMolecular weight:548.11Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2BAY-2402234
CAS:BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Formula:C21H18ClF5N4O4Purity:98.90%Color and Shape:SolidMolecular weight:520.84Ref: TM-T14501
1mg173.00€2mg246.00€5mg368.00€10mg567.00€25mg905.00€50mg1,225.00€100mg1,644.00€1mL*10mM (DMSO)424.00€Gallium maltolate
CAS:Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.Formula:C18H15GaO9Purity:99.67% - 99.75%Color and Shape:SolidMolecular weight:445.03Stigmatellin
CAS:Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.Formula:C30H42O7Color and Shape:SolidMolecular weight:514.65MGB-BP-3
CAS:MGB-BP-3 is a synthetic antibiotic with bactericidal activity that inhibits bacterial DNA replication and can be used to study recurrent C. difficile infections.Formula:C36H37N7O4Purity:97.06% - 98.92%Color and Shape:SolidMolecular weight:631.72WRN inhibitor 11
CAS:WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.Formula:C34H35ClF3N9O5Color and Shape:SolidMolecular weight:742.15HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Formula:C24H27FN4O5Color and Shape:SolidMolecular weight:470.495-Methylcytosine
CAS:5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.Formula:C5H7N3OPurity:99.17%Color and Shape:SolidMolecular weight:125.133-AP
CAS:3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).Formula:C7H9N5SPurity:97.33% - 99.75%Color and Shape:SolidMolecular weight:195.24Ref: TM-T1982
2mg39.00€5mg57.00€10mg69.00€25mg150.00€50mg264.00€100mg400.00€500mg909.00€1mL*10mM (DMSO)57.00€DAM-IN-1
CAS:DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.Formula:C16H17NO4Purity:98%Color and Shape:SolidMolecular weight:287.31Xanthopterin (hydrate)
CAS:Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.Formula:C6H7N5O3Purity:99.79%Color and Shape:Yellow To Orange Crystalline PowderMolecular weight:197.15Garenoxacin mesylate hydrate
CAS:Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strainsFormula:C23H20F2N2O4·CH4O3S·H2OPurity:99.56%Color and Shape:SolidMolecular weight:540.53L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11PT-129
PT-129 is a RPOTAC degrader that targets the G3BP1/2NTF2 domain (protein-RNA interaction site), facilitating the breakdown of intracellular stress granules. It prevents the formation of stress granules in stressed cells and deconstructs existing ones, thereby disrupting ATF4 transmission and inhibiting cancer cell proliferation. Stress granules (SGs) are membraneless cytoplasmic compartments formed under stress, which aid in the transfer of ATF4 from fibroblasts to tumor cells, promoting fibroblast-related tumor growth. G3BP1/2 serve as central proteins in the SG network, and inhibiting them may reduce the stress resilience of cancer cells within the tumor microenvironment. PT-129 consists of a target protein ligand (red part) G3BP1/2-Targeting ligand-1, an E3 ligase ligand (blue part) Thalidomide 4-fluoride, and a PROTAC linker (black part) Amino-PEG3-C2-acid; the E3 ligase ligand and linker form the complex Thalidomide-NH-PEG3-propionic acid.Formula:C46H48N8O12SColor and Shape:SolidMolecular weight:936.98
