DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Products of "DNA/RNA Synthesis"
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Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:100% - 99.93%Color and Shape:SolidMolecular weight:533.95SR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Formula:C26H32O2Purity:98%Color and Shape:SolidMolecular weight:376.53Ref: TM-T23384
1mg137.00€5mg492.00€10mg797.00€25mg1,385.00€50mgTo inquire100mgTo inquire1mL*10mM (DMSO)550.00€Nedaplatin
CAS:Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.Formula:C2H8N2O3PtPurity:100% - 98.69%Color and Shape:Straw Yellow PowderMolecular weight:303.17Ancitabine hydrochloride
CAS:Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.Formula:C9H12ClN3O4Purity:99.02% - 99.37%Color and Shape:White SolidMolecular weight:261.66Saccharin 1-methylimidazole
CAS:Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.Formula:C7H5NO3S·C4H6N2Purity:98.21%Color and Shape:SolidMolecular weight:265.29Farudodstat
CAS:Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH with antitumor activity. It has the potential to be a first-in-class candidate in AML.Formula:C19H14F2N2O3Purity:98.36%Color and Shape:SolidMolecular weight:356.32Bleomycin Sulfate
CAS:Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis.Formula:C55H85N17O25S4Purity:100% - ≥98%Color and Shape:Less Or Yellowish Powder Possible Bluish Color Depending On Copper Content (Ntp 1992)Molecular weight:1523 (average)Bersiporocin
CAS:Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.Formula:C15H19Cl2N3OPurity:100% - 98.88%Color and Shape:SolidMolecular weight:328.24Epirubicin hydrochloride
CAS:Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.Formula:C27H30ClNO11Purity:98.13% - 99.79%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.98Ref: TM-T0125
2mg39.00€5mg56.00€10mg88.00€25mg150.00€50mg240.00€100mg324.00€500mg785.00€1mL*10mM (DMSO)73.00€HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29WRN inhibitor 14
WRN inhibitor 14 (compound S35) is an orally administered WRN inhibitor with anticancer properties. It effectively suppresses tumor growth in the SW48 xenograft model in BALB/c nude mice.Formula:C35H40F4N10O5Color and Shape:SolidMolecular weight:756.75NSAH
CAS:NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-Formula:C18H14N2O3Purity:99.27%Color and Shape:SolidMolecular weight:306.32Ref: TM-T8800
5mg70.00€10mg111.00€25mg216.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)77.00€BMVC-8C3O
CAS:BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.Formula:C42H53I3N4O3Purity:99.72%Color and Shape:SolidMolecular weight:1042.61Ref: TM-T13584
1mg106.00€5mg202.00€10mg301.00€25mg487.00€50mg658.00€100mg905.00€200mg1,216.00€1mL*10mM (DMSO)393.00€GTSE1-IN-1
CAS:GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.Formula:C21H24FN7Color and Shape:SolidMolecular weight:393.46Werner syndrome RecQ helicase-IN-2
CAS:Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.Formula:C32H34F3N9O5Purity:99.02%Color and Shape:SolidMolecular weight:681.67Thymidine
CAS:Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.Formula:C10H14N2O5Purity:99.27% - ≥95%Color and Shape:White To Off-White Solid CrystallineMolecular weight:242.23JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Formula:C20H16Cl3N3O4Purity:99.29%Color and Shape:SolidMolecular weight:468.72Ref: TM-T15611
1mg47.00€5mg87.00€10mg160.00€25mg354.00€50mg620.00€100mg1,103.00€1mL*10mM (DMSO)90.00€Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purity:98.83%Color and Shape:SolidMolecular weight:378.46Ref: TM-T6823
1mg50.00€2mg72.00€5mg107.00€10mg167.00€25mg304.00€50mg500.00€100mg725.00€200mg1,017.00€500mg1,510.00€1mL*10mM (DMSO)88.00€N2-methylguanine
CAS:N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.Formula:C6H7N5OPurity:98.74%Color and Shape:SolidMolecular weight:165.15Nusinersen
CAS:Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.Color and Shape:SolidCarboplatin
CAS:Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.Formula:C6H12N2O4PtPurity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:371.25CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formula:C27H27N7O2SPurity:95.44% - 99.25%Color and Shape:SolidMolecular weight:513.61BVDU 5′-Triphosphate
CAS:BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.Formula:C11H16BrN2O14P3Purity:98%Color and Shape:SolidMolecular weight:573.08Valacyclovir hydrochloride
CAS:Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that inhibits viral DNA replication after metabolization.Formula:C13H20N6O4·HClPurity:100% - ≥95%Color and Shape:White To Off-White Crystalline PowerMolecular weight:360.8Ref: TM-T1087
1g299.00€10mg47.00€25mg69.00€50mg85.00€100mg97.00€200mg127.00€500mg202.00€1mL*10mM (DMSO)47.00€CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formula:C12H14N2OSPurity:96.50%Color and Shape:SolidMolecular weight:234.32Poly(A) polymerase
CAS:Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3' end of RNA, a process that involves integrating ATP as AMP.Purity:98%Color and Shape:Solid5-Fluoroorotic acid
CAS:5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Formula:C5H3FN2O4Purity:100% - 99.7%Color and Shape:White To Pale Yellow PowderMolecular weight:174.09Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Formula:C10H14N2Na3O14P3Purity:96.00%Color and Shape:White Amorphous PowderMolecular weight:548.11Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formula:C8H18N3O8PPurity:99.44%Color and Shape:SolidMolecular weight:315.22Metarrestin
CAS:Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.Formula:C31H30N4OPurity:99.45%Color and Shape:SolidMolecular weight:474.6Ref: TM-T12006
1mg40.00€2mg52.00€5mg88.00€10mg144.00€25mg298.00€50mg512.00€100mg740.00€500mg1,539.00€RG7800 tetrahydrochloride
RG7800 hydrochloride is an orally active modulator of SMN2 splicing, exhibiting EC50 values of 23 nM for SMN2 splicing and 87 nM for SMN protein production.Formula:C24H32Cl4N6OPurity:98%Color and Shape:SolidMolecular weight:562.36Cynaroside
CAS:Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.Formula:C21H20O11Purity:98% - 99.83%Color and Shape:SolidMolecular weight:448.38Ref: TM-T3376
1mg40.00€5mg85.00€10mg115.00€25mg225.00€50mg396.00€100mg590.00€500mg1,264.00€1mL*10mM (DMSO)93.00€1-Hydroxyanthraquinone
CAS:1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.Formula:C14H8O3Purity:98.83%Color and Shape:Orange Red Needles Red-Orange To Fine Yellow CrystalsMolecular weight:224.21DNA Gyrase-IN-9
DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase.Formula:C26H18ClN3O2Purity:98%Color and Shape:SolidMolecular weight:439.89DNA Gyrase-IN-8
CAS:DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].Formula:C19H14BrN5OPurity:98%Color and Shape:SolidMolecular weight:408.25ZIM
CAS:ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Formula:C20H19N3O3Purity:99.13%Color and Shape:SolidMolecular weight:349.38Ref: TM-T72024
5mg39.00€10mg58.00€25mg105.00€50mg170.00€100mg271.00€200mg398.00€1mL*10mM (DMSO)52.00€ISOPIMPINELLIN
CAS:Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.Formula:C13H10O5Purity:98.74% - 99.71%Color and Shape:SolidMolecular weight:246.22CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formula:C16H18N2O7SPurity:100.00%Color and Shape:SolidMolecular weight:382.39
