DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Products of "DNA/RNA Synthesis"
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TH287 hydrochloride
CAS:TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.Formula:C11H11Cl3N4Purity:99.5%Color and Shape:SolidMolecular weight:305.59RNA polymerase II-IN-1
CAS:RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.Formula:C38H53N11O12SPurity:98%Color and Shape:SolidMolecular weight:887.96ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.32Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formula:C11H16ClN5Purity:99.6%Color and Shape:SolidMolecular weight:253.73BI8622
CAS:BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.Formula:C25H26N6OPurity:98.28%Color and Shape:SolidMolecular weight:426.51Butylparaben sodium
CAS:Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1Formula:C11H13NaO3Purity:98%Color and Shape:SolidMolecular weight:216.21Lucanthone
CAS:Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formula:C20H24N2OSPurity:99.92%Color and Shape:Yellow Crystals From Alcohol SolidMolecular weight:340.48Ref: TM-T4569
1mg56.00€2mg80.00€5mg126.00€10mg188.00€25mg400.00€50mg592.00€100mg837.00€1mL*10mM (DMSO)140.00€COH1
CAS:COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].Formula:C11H10N2O3SPurity:98%Color and Shape:SolidMolecular weight:250.27Madrasin
CAS:Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Formula:C16H17N5O2Purity:99.44% - 99.61%Color and Shape:SolidMolecular weight:311.34ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Formula:C17H21ClN2O4SPurity:99.33% - 99.45%Color and Shape:SolidMolecular weight:384.882-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Formula:C5H4FN5Purity:99.49%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:153.123,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:97.28%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.06GS-441524
CAS:GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.Formula:C12H13N5O4Purity:98.78% - 99.75%Color and Shape:SolidMolecular weight:291.26IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:351.4Ref: TM-T8841
1mg81.00€5mg170.00€10mg301.00€25mg563.00€50mg805.00€100mg1,111.00€1mL*10mM (DMSO)188.00€PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:SolidMolecular weight:453.9Ref: TM-T84770
1mg92.00€5mg188.00€10mg313.00€25mg603.00€50mg840.00€100mg1,169.00€200mg1,586.00€1mL*10mM (DMSO)216.00€DMT-dU-CE Phosphoramidite
CAS:DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.Formula:C39H47N4O8PPurity:97.58%Color and Shape:SolidMolecular weight:730.79Antiviral agent 36
Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100Formula:C30H32N4O3Purity:98%Color and Shape:SolidMolecular weight:496.6Votoplam HCl
CAS:Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).Formula:C21H26ClN9OPurity:99.49%Color and Shape:SoildMolecular weight:455.94Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurity:99.54% - 99.62%Color and Shape:SolidMolecular weight:493.57Rifalazil
CAS:Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.Formula:C51H64N4O13Purity:98%Color and Shape:SolidMolecular weight:941.07
