DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Products of "DNA/RNA Synthesis"
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AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Formula:C17H19F3N4O3SPurity:99.96%Color and Shape:SolidMolecular weight:416.42WRN inhibitor 16
WRN inhibitor 16 (Example 83) is an orally active WRN inhibitor. In a SW48 xenograft mouse tumor model, WRN inhibitor 16 did not cause tumor regression.Formula:C31H30F4N4O5SColor and Shape:SolidMolecular weight:646.65Floxuridine
CAS:Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formula:C9H11FN2O5Purity:98.92% - 99.96%Color and Shape:SolidMolecular weight:246.19Lomibuvir
CAS:Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.Formula:C25H35NO4SPurity:100%Color and Shape:SolidMolecular weight:445.61Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purity:98.4% - 99.54%Color and Shape:SolidMolecular weight:956.68Ref: TM-TQ0184
1mg73.00€5mg155.00€10mg219.00€25mg465.00€50mg692.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)266.00€Folic acid
CAS:Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.Formula:C19H19N7O6Purity:99.19% - 99.27%Color and Shape:Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FMolecular weight:441.4N-Nitrosodiethylamine
CAS:N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine.Formula:C4H10N2OPurity:99.26% - ≥98%Color and Shape:SolidMolecular weight:102.14Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05360A
CAS:360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5Fludarabine
CAS:Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formula:C10H12FN5O4Purity:100% - 99.88%Color and Shape:White SolidMolecular weight:285.23MM41
CAS:MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.Formula:C44H66N10O6Purity:97.13%Color and Shape:SolidMolecular weight:831.06Ref: TM-T60028
1mg52.00€5mg116.00€10mg178.00€25mg293.00€50mg393.00€100mg520.00€200mg712.00€1mL*10mM (DMSO)160.00€(S)-crizotinib
CAS:(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.Formula:C21H22Cl2FN5OPurity:98.52% - 99.47%Color and Shape:SolidMolecular weight:450.34Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Formula:C7H7NO4Purity:96.85%Color and Shape:SolidMolecular weight:169.13DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formula:C14H11F3N2O2Purity:99.74%Color and Shape:SolidMolecular weight:296.24Ref: TM-T12438
1mg50.00€5mg106.00€10mg160.00€25mg311.00€50mg472.00€100mg695.00€200mg938.00€1mL*10mM (DMSO)97.00€Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formula:C14H12N4OSPurity:97.91%Color and Shape:SolidMolecular weight:284.34Ref: TM-T4228
1mg42.00€2mg50.00€5mg90.00€10mg148.00€25mg240.00€50mg430.00€100mg633.00€1mL*10mM (DMSO)96.00€Fialuridine
CAS:Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Formula:C9H10FIN2O5Purity:99.71% - 99.90%Color and Shape:Less Crystals Colourless CrystalsMolecular weight:372.09Ref: TM-T7655
1mg35.00€5mg74.00€10mg116.00€25mg235.00€50mg373.00€100mg562.00€500mg1,216.00€1mL*10mM (DMSO)82.00€Enoxacin
CAS:Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formula:C15H17FN4O3Purity:98.68% - 99.89%Color and Shape:Off-White To Yellow CrystalsMolecular weight:320.32POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂,IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。Formula:C21H20N6Purity:98%Color and Shape:SolidMolecular weight:356.42Foscarnet sodium
CAS:Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.Formula:CNa3O5PPurity:98.52%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:191.95
