DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Products of "DNA/RNA Synthesis"
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13-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formula:C12H19F2N6O12P3Color and Shape:SolidMolecular weight:570.23Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formula:C6H11N3O4Purity:98.81%Color and Shape:SolidMolecular weight:189.17N1-Methylpseudouridine
CAS:N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms byFormula:C10H14N2O6Purity:100% - 99.14%Color and Shape:SolidMolecular weight:258.23SR18662
SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.Formula:C16H19Cl2N3O4SPurity:98.97% - 99.2%Color and Shape:SolidMolecular weight:420.31Ref: TM-T22429
1mg48.00€5mg96.00€10mg160.00€25mg311.00€50mg502.00€100mg718.00€200mg938.00€500mg1,454.00€1mL*10mM (DMSO)105.00€Laromustine
CAS:Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Formula:C6H14ClN3O5S2Color and Shape:SolidMolecular weight:307.785-Fluorouridine 5'-phosphate
CAS:5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.Formula:C9H12FN2O9PColor and Shape:SolidMolecular weight:342.1722-Keto-D-galactose
CAS:2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formula:C6H10O6Purity:98%Color and Shape:SolidMolecular weight:178.14Zn(BQTC)
CAS:Zn(BQTC) inhibits mtDNA and nDNA, damages mitochondria/nuclei, triggers apoptosis, and targets A549R cancer cells.Formula:C30H36Cl2N5O3ZnPurity:98%Color and Shape:SolidMolecular weight:650.92IBR2
CAS:IBR2 is a potent RAD51 inhibitor that disrupts DNA repair, inhibits cancer cell growth, and induces apoptosis.Formula:C24H20N2O2SPurity:96.15%Color and Shape:SolidMolecular weight:400.49Ref: TM-T11600
1mg35.00€5mg70.00€10mg111.00€25mg183.00€50mg259.00€100mg359.00€200mg532.00€1mL*10mM (DMSO)77.00€N-desmethyl Netupitant
CAS:N-desmethyl Netupitant is a metabolite of Netupitant and a potential Substance-P receptor agonist.Formula:C29H30F6N4OPurity:98%Color and Shape:SolidMolecular weight:564.57Cinoxacin
CAS:Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.Formula:C12H10N2O5Purity:99.62% - 99.98%Color and Shape:SolidMolecular weight:262.225-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purity:99.89%Color and Shape:White PowderMolecular weight:323.1Fosifloxuridine nafalbenamide
CAS:Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53Ref: TM-T33762
1mg88.00€5mg160.00€10mg216.00€25mg393.00€50mg550.00€100mg753.00€500mg1,549.00€1mL*10mM (DMSO)210.00€Ro5-3335
CAS:Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.Formula:C13H10ClN3OPurity:99.42% - 99.50%Color and Shape:SolidMolecular weight:259.69VVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formula:C20H21F2N3O4SPurity:99.24%Color and Shape:SoildMolecular weight:437.46ML-60218
CAS:ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.Formula:C19H15Cl2N3O2S2Purity:98.1%Color and Shape:SolidMolecular weight:452.38Ref: TM-T40661
1mg56.00€5mg119.00€10mg187.00€25mg411.00€50mg638.00€100mg908.00€200mg1,225.00€1mL*10mM (DMSO)131.00€Favipiravir
CAS:Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.Formula:C5H4FN3O2Purity:98.16% - 99.71%Color and Shape:SolidMolecular weight:157.16-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Formula:C4H5N3O2Purity:99.47%Color and Shape:SolidMolecular weight:127.1Thiarabine
CAS:Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.Formula:C9H13N3O4SPurity:98%Color and Shape:SolidMolecular weight:259.28
