Antibiotic

Antibacterialagent 244 is a compound that exhibits broad-spectrum antibacterial activity and oral efficacy, primarily targeting Gram-positive bacteria with a minimum inhibitory concentration (MIC) of 1-4 μg/mL. It possesses low hemolytic toxicity (HC50 of 111.6 μg/mL). The mode of action for Antibacterialagent 244 involves disrupting the bacterial transmembrane potential and increasing membrane permeability, which leads to the leakage of cellular contents such as DNA and proteins, ultimately causing bacterial death. This compound is useful in research related to infections caused by Gram-positive bacteria.

Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM), and this inhibition was largely attributable to the presence of zinc.

Chitin synthase inhibitor 4: a CHS inhibitor with antimicrobial properties, potential fungicide.

Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic

Dalbavancin (BI-397) is a lipoglycopeptide antibiotic effective against Gram-positive pathogens, MRSA, MRSE, with MIC90s of 0.06-0.25 μg/mL.

Daptomycin (LY146032) is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.

(-)-cis-Myrtanol, a terpenoid compound derived from Artemisia dracunculus, exhibits effective antimicrobial activity against harmful gut bacteria such as Bifidobacterium bifidum.

Bedaquiline, an anti-TB drug, blocks mycobacterial ATP synthesis, effective against all Mycobacterium tuberculosis states.

Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.

Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.

Toltrazuril (Toltrazurilo), an antiprotozoal agent, has effect on Coccidia parasites.

Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that impedes bacterial proliferation [1].

Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.

Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.

Cefoperazone sodium salt (CP 52640-2) is broad-spectrum cephalosporin with a tetrazolyl moiety, used to treat Pseudomonas infections.

Sulfadimethoxine (Sulphadimethoxine) is a sulfanilamide that is used as an anti-infective agent.

Triclosan (Irgasan) is an antibacterial and antifungal agent.

Cefmenoxime hydrochloride: cephalosporin antibiotic, IV/IM, targets gram-positive/negative bacteria, beta-lactamase resistant, effective, low side effects.

Eperezolid (PNU-100592), an oxazolidinone antibiotic, inhibits staphylococci (MIC90=1-4 mg/ml) effectively, methicillin resistance notwithstanding.

Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).

Sisomicin sulfate (Pathomycin), a broad-spectrum antibiotic from Micromonospora inyoensis, is strongest against gram-positive bacteria.

Leucomycin (Turimycin) is a macrolide antibiotic.

Isoconazole nitrate (Fazol) (Travogen) is an azole antifungal reagent.

Cephalexin monohydrate (Cephalexin hydrate) is a cephalosporin antibiotic with significant antibacterial activity that inhibits bacterial proliferation.

Sulbactam (CP45899) is a semi-synthetic inhibitor that enhances antibiotics by blocking beta-lactamase.

Actinoidin A is a glycopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

Amoxicillin inactivates bacterial cell wall proteins, disrupting peptidoglycan cross-linking, which weakens walls and causes cell lysis.

Kasugamycin hydrochloride (Kasumin), an antibiotic from Streptomyces, discovered in 1965 by Hamao Umezawa, combats rice blast fungus.

Sanfetrinem (GV104326) sodium is a β-lactamase antibiotic with antimicrobial activity for the study of bacterial infections.

2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant.

7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.

Cefaclor (Panoral) is a cephalosporin antibiotic.

Cefdinir (FK-482), a semi-synthetic third-gen cephalosporin antibiotic, treats ear, sinus, throat, and skin infections.

Cilastatin (MK0791): protects imipenem from renal breakdown; inhibits leukotriene D4 metabolism.

Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.

Davercin (Erythromycin Cyclocarbonate), a Erythromycin derivative, exhibits efficacy against both Gram-positive and select Gram-negative microorganisms.

Cefathiamidine treats respiratory, liver, senses, urinary infections, endocarditis, and sepsis with broad antibacterial properties.

Arisostatin B is a tetracycline antibiotic (antibiotic) with activity against Gram-positive bacteria and tumor cells.

Isothiouronium, a functional group, is the acid salt of isothiourea.

Arylomycin B4 is a lipidic hexapeptide antibiotic (antibiotic) targeting Gram-positive bacteria.

Arylomycin B1 is a lipid hexapeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

Procaine penicillin G treats syphilis, anthrax, oral infections, pneumonia, diphtheria, cellulitis, and bites.

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast

Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.

Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (

SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under

Azithromycin (CP 62993) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.

Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral

Isepamicin sulfate (sch21420), an aminoglycoside, targets 30S ribosomal unit, effective against type I 6-acetyltransferase strains.

Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.

Penicillin G potassium (Benzylpenicillin potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.

Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.

Valnemulin hydrochloride (Valnemulin HCl), a broad-spectrum bacteriostatic agent, inhibits protein synthesis in bacteria by binding to the peptidyl transferase.

Nanchangmycin, a polyether antibiotic similar to dianemycin, effectively combats diverse nematodes and insects, not mammals/plants.

EDTA copper(II) disodium salt is a metal chelator with antimicrobial, anti-inflammatory, and antioxidant activities for the study of neurological disorders.

Cephalothin is a beta-lactam antibiotic, inhibits class C β-lactamase AmpC (Ki: 0.32 μM).

Flumequine (R-802) is a broad-spectrum antibiotic targeting DNA gyrase and topoisomerase IV in Gram-positive and Gram-negative bacteria.

Butenafine hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, inhibiting the synthesis of sterols by inhibiting squalene epoxidase.

Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.

Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.

Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.

Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.

Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum.

Chlortetracycline HCl (Isphamycin): broad-spectrum, bacteriostatic, halts protein synthesis in bacteria and protozoa.

Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.

Mtb-IN-10 (Compound P15) is an Rv1625c/Cya activator that influences the growth of Mycobacterium tuberculosis (Mtb) by modulating cAMP metabolism. It demonstrates an anti-tuberculosis activity with an EC50 of 1.96 µM in Mtb-infected macrophage models and achieves an oral bioavailability of 58.0% when administered orally to mice at 20 mg/kg. Mtb-IN-10 potentially regulates intracellular signaling and disrupts cholesterol metabolism within Mtb, thereby inhibiting bacterial proliferation. It holds promise for tuberculosis (TB) research, particularly targeting multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains of Mtb.

Arisostatin A is a secondary metabolite produced by microorganisms, recognized as an antibiotic (antibiotic) with activity against Gram-positive bacteria. This compound also exhibits potent antitumor properties. It induces apoptosis (apoptosis) by activating caspase-3 and generating reactive oxygen species (ROS) in AMC-HN-4 cells.

Q203 (Telacebec) is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB and inhibits M. tuberculosis H37Rv (MIC50: 2.7 nM).

Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.

Kasugamycin (Ksg) HCl hydrate blocks translation initiation in canonical mRNAs, not leaderless ones, by competing with initiator tRNA.

Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.

Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.

Cefpirome sulfate (HR-810 sulfate) is a fourth generation cephalosporin antibiotic.

Thiacetazone (Diazam) is a thiosemicarbazone that thioacetazone treatment of pulmonary tuberculosis

Carbadox, an antibacterial for swine dysentery and growth promotion, is banned in the UK due to carcinogen and mutagen risks.

Saptomycin E is an antitumor antibiotic.

Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.

Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.

Sulfabenzamide (N-Sulfanilylbenzamide) is a sulfonamide antibacterial agent used alone or with sulfathiazole and sulfacetamide as a topical, intravaginal

Oxiconazole nitrate (Ro 13-8996) is an antifungal imidazole inhibiting fungal growth by blocking ergosterol synthesis, disrupting cell membranes.