Antibiotic

Nitrofurantoin, an antibiotic, targets bacteria for urinary infections by blocking DNA, RNA, and protein synthesis.

Arylomycin A3 is a lipopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.

Pafuramidine (DB289) is an experimental prodrug of the metabolite DB75, an antiparasitic compound with antimalarial activity.

Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.

Carsalam (2H-1,3-Benzoxazine-2,4(3H)-dione) is a nonsteroidal anti-inflammatory drug.

Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities.

Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.

Rosoxacin (Acrosoxacin) shows antibacterial activities against a broad spectrum of Gram-negative bacteria including Neisseria gonorrhoeae (MIC90 = 0.03mg/ml).

Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic.

Aerocavin is an antibiotic (antibiotic) that exhibits activity against both Gram-positive and Gram-negative bacteria in vitro [in vitro].

Dalfopristin (RP54476), a semi-synthetic streptogramin, treats multi-resistant Enterococcus faecium.

Cefoxitin sodium (Betacef) is a semisynthetic cephamycin antibiotic resistant to beta-lactamase.

Pivmecillinam HCl, an oral prodrug of mecillinam, is a broad-spectrum penicillin effective against gram-negative bacteria.

Cefquinome Sulfate is a semisynthetic, broad-spectrum, fourth-generation aminothiazolyl cephalosporin with antibacterial activity.

Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide

Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive

5Z-7-Oxozeaenol: TGF-β-activated kinase 1 inhibitor, IC50 8.1 nM; VEGF-R2 inhibitor, IC50 52 nM; weak MEK1 inhibitor, IC50 411 nM.

3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections.

Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated

Fenticonazole Nitrate (Lomexin) is an azole agent with antifungal activity.

Sorbic acid is a natural product that inhibits various bacteria, including sporeformers,

Lincomycin hydrochloride monohydrate (Lincomycin hydrochloride hydrate) is an antibiotic produced by Streptomyces lincolnensis var.

Concanavalin A is a natural product, a phytoalexin. Concanavalin A has antitumor activity and can also induce acute liver injury. Cost effective and quality assured.

Buparvaquone (BW 720C) is a hydroxynaphthoquinone antiprotozoal drug related to atovaquone and parvaquone.

Amythiamicin A is an antibiotic effective against gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), and exhibits activity against Plasmodium falciparum.

Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in cells.

Gastric mucin, a large glycoprotein, protects the gut from acid, enzymes, microbes, and physical damage.

Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a

Malolactomycin C (compound 1) is a macrocyclic lactone antifungal antibiotic isolated from the Streptomyces strain KP-3144. It effectively inhibits Botrytis cinerea (gray mold), thereby controlling various plant diseases, including gray mold infections.

Vineomycin A1 (OS-4742 A1) is an antibiotic effective against Gram-positive bacteria, identified in *Streptomyces matensis* subsp. vineus. It has also demonstrated antitumor activity in mice and holds potential for research in skin fibrosis.

Cefaclor monohydrate (Cefaclorum) is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.

Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.

Cefixime is a broad-spectrum third-gen cephalosporin antibiotic, stable against beta-lactamases and more effective on gram-negative bacteria.

Thioisonicotinamide (Isothionicotinamide) is a chemical based on the nicotinamide structure, but in which the amide is in the 4-position and not the 3-position.

KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.

Chlorhexidine is a biguanide antiseptic targeting bacteria, damaging cell membranes and causing cell death, more effective against gram-positive types.

Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.

DuP-721: broad-spectrum, oral antibiotic targeting various bacteria, including M. tuberculosis.

Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.

Cephalothin sodium, a first-gen cephalosporin antibiotic, disrupts bacterial cell walls by inactivating penicillin-binding proteins, leading to cell lysis.

Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.

Tiamulin (Thiamutilin) is a semisynthetic pleuromutilin antibiotic

Cetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.

Lanopepden (GSK 1322322) is a potent peptide desmethylase inhibitor that inhibits Staphylococcus aureus and can be used to study infectious diseases.

Nisin A: a lantibiotic peptide made by L. lactis, contains unique amino acids like lanthionine, and fights bacteria.

Oral 3rd-gen cephalosporin antibiotic; treats ear, throat, sinus infections; active vs. Gram+ & Gram- bacteria; Cefpodoxime proxetil is a prodrug.

Ampicillin Sodium, a broad-spectrum aminopenicillin derivative, inhibits bacterial growth by blocking cell wall peptidoglycan synthesis.

Cefodizime Sodium is a third generation cephalosporin antibiotic, has broad-spectrum activity

Cefuroxime Sodium: a second-gen cephalosporin antibiotic resistant to beta-lactamase, halts bacterial wall synthesis, causing cell lysis.

Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity.

Ceftiofur sodium (Naxcel), an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.

Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.

Compound 6d (Antibacterial agent 159) is an antibiotic effective against impetigo and Clostridium difficile infection (CDI), with no observed recurrence for CDI

Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains

NITD-916: oral Mycobacterium InhA inhibitor (IC50: 570 nM), lipophilic 4-hydroxy-2-pyridone with antituberculosis action.

Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.

Delpazolid (LCB01-0371) is an oxazolidinone that's effective against Gram-positive bacteria and more active than linezolid in systemic infections.

10-Undecenoic acid (Undecylenic acid) is a natural or synthetic fungistatic fatty acid, with antifungal activity.

Delamanid (OPC-67683), a nitro-dihydro-imidazooxazole, is an anti-TB drug that blocks mycolic acid synthesis in bacterial walls.

Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock.

Sulfamethazine (Sulfadimidine) is a sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.

TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).

ML318, a biaryl nitrile, inhibits PvdQ acylase (IC50=20nM) and P. aeruginosa growth (IC50=19µM), blocking pyoverdine production under low iron.

Clindamycin HCl monohydrate inhibits Staph aureus protein synthesis, suppresses virulence factors, resistance via 50S rRNA methylation.

Citric Acid Monohydrate: tricarboxylic, from citrus, antioxidant, stabilizes drugs, preservative.

Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.

Potassium sorbate, an antifungal and corrosion inhibitor, is used with polyethylene films.

Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.

Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity.

Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.

Meropenem (SM 7338), a broad-spectrum IV antibiotic, treats severe infections but may cause mild liver enzyme elevations or rare cholestatic injury.

Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).

Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein

Doripenem monohydrate (S 4661 monohydrate) is a broad-spectrum injectable antibiotic, used for Gram-positive, Gram-negative and anaerobic pathogens.

Sarafloxacin hydrochloride (A-56620 (hydrochloride)), a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.

Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.