Antibacterial

Imipenem monohydrate (Imipenem) is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall. Cost-effective and quality-assured.

Applications D-Tyrosine-d2 is deuterium labelled D-Tyrosine (T899970). D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic polypropylene surfaces. References Li, Ji. et al.: Chin. Chem. Lett., 23, 647 (2012); Xu, H. et al.: Water Res., 45, 5796 (2011); Ke, W. et al.: Antimicrob. Agents Chemother., 55, 174 (2011)

Monoctanoin (Glyceryl 1-caprylate) has antibacterial activity against Staphylococcus aureus and Escherichia coli.

Stability Hygroscopic Applications Descladinose 6-N-Desmethyl Azithromycin is a metabolite of Azithromycin (A927018), which is an azalide macrolide antibiotic. References Hunter, R., et al.: J. Vet. Pharmacol. Ther., 26, 117 (2003);

Ridinilazole, a narrow-spectrum antibiotic, strongly inhibits C. difficile, outperforming metronidazole and vancomycin.

Applications Fluorinated quinolone antibacterial. References Stilwell, G., et al.: Antimicrob. Agents Chemother., 7, 483 (1975), Rohlfing, S.R., et al.: J. Antimicrob. Chemother., 3, 615 (1977),

Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities.

Applications Sulfatroxazole is a component present in various veterinary drugs. Possible antibacterial activity due to presence of sulfonamide moiety in the structure. References Gomez-Perez, M. et al.: J. Chrom. A., 1248, 130 (2012); Mengelers, M. et al.: J. Vet. Pharmacol. Ther., 20, 276 (1997);

Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase.

Applications Oxacillin Penillic Acid Disodium Salt, is a derivative (impurity) of Oxacillin which is used as an antibiotic related to Penicillin. Antibacterial. References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971)

Sulfadiazine sodium (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.

TBA-7371 (DprE1-IN-1) is a potent inhibitor of DprE1 and PDE6.

Moxifloxacin (Avelox), a 4th-gen fluoroquinolone, fights Gram-positive/negative bacteria and drug-resistant S. pneumoniae.

Closthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against MRSA, Ec, VRE, and Mv (MICs: 0.58 μM, 9.00 μM, 0.58 μM and 72.03 μM).

Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.

Stability Hygroscopic Applications Semisynthetic aminoglycoside antibiotic, related to sisomicin. Antibacterial. References Miller, G.H., et al.: Antimicrob. Agents Chemother., 10, 827 (1976), Raab, W., et al.: Adv. Clin. Pharmacol., 15, 91 (1978), Noone, P., et al.: Drugs, 27, 548 (1984),

Sulfasymazine is a sulfonamide drug.

Stability Hygroscopic Applications Baquiloprim is an amiopyrimidine antibacterial synergist with high activity and slow elimination. Baquiloprim has a better half-life than trimethoprim. References Zhi-hui, H., et al.: Anhui Nongye Kexue, 41, 2503 (2013)

Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells.