PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Products of "PI3K"
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Heterophyllin B
CAS:Heterophyllin B hinders esophageal cancer cell adhesion/invasion via PI3K/AKT/β-catenin and gene regulation.Formula:C40H58N8O8Purity:99.12% - 99.55%Color and Shape:SolidMolecular weight:778.94LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Nemiralisib
CAS:Nemiralisib (GSK-2269557) is an oral PI3Kδ inhibitor (pKi 9.9) for treating respiratory diseases like COPD.Formula:C26H28N6OPurity:99.91%Color and Shape:SolidMolecular weight:440.54PI3Kα-IN-13
CAS:PI3Kα-IN-13 (Compound 18a), a PI3Kα inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis and hampers the proliferation of various cancer cell lines,Formula:C21H19N5O3Purity:98%Color and Shape:SolidMolecular weight:389.41PIK-108
CAS:PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).Formula:C22H24N2O3Purity:98.92%Color and Shape:SolidMolecular weight:364.44Ref: TM-T28416
1mg40.00€2mg57.00€5mg97.00€10mg156.00€25mg255.00€50mg368.00€100mg510.00€200mg700.00€1mL*10mM (DMSO)105.00€Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formula:C21H22O11Purity:97.53% - 98.63%Color and Shape:SolidMolecular weight:450.39α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Formula:C18H30O2Purity:98.19% - 99.81%Color and Shape:Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:278.43CGS 15943
CAS:CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.Formula:C13H8ClN5OPurity:99.63%Color and Shape:SolidMolecular weight:285.69ETP-45658
CAS:ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).Formula:C16H17N5O2Purity:99.13%Color and Shape:SolidMolecular weight:311.34Ref: TM-T25399
1mg52.00€5mg111.00€10mg175.00€25mg316.00€50mg512.00€100mg747.00€1mL*10mM (DMSO)124.00€Leniolisib
CAS:Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).Formula:C21H25F3N6O2Purity:99.88%Color and Shape:SolidMolecular weight:450.46VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formula:C21H25N7OPurity:98.60%Color and Shape:SolidMolecular weight:391.47Ref: TM-T7944
1mg66.00€5mg144.00€10mg227.00€25mg399.00€50mg567.00€100mg753.00€200mg1,035.00€1mL*10mM (DMSO)166.00€GDC-0326
CAS:GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).Formula:C19H22N6O3Purity:100% - 99.35%Color and Shape:SolidMolecular weight:382.42Ref: TM-T3985
1mg35.00€2mg49.00€5mg95.00€10mg155.00€25mg255.00€50mg406.00€100mg592.00€1mL*10mM (DMSO)94.00€APY0201
CAS:APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.Formula:C23H23N7OPurity:98% - 99.21%Color and Shape:SolidMolecular weight:413.48Alpelisib
CAS:Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity.Formula:C19H22F3N5O2SPurity:98% - 99.73%Color and Shape:SolidMolecular weight:441.47Ref: TM-T1921
1g653.00€5mg55.00€10mg72.00€25mg87.00€50mg96.00€100mg154.00€200mg265.00€500mg447.00€1mL*10mM (DMSO)60.00€Sophocarpine
CAS:Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formula:C15H22N2OPurity:98.67%Color and Shape:SolidMolecular weight:246.35IHMT-PI3K-315
IHMT-PI3K-315 (20e) serves as a potent, selective inhibitor of PI3Kγ/δ, exhibiting IC 50 values of 4.0 nM for PI3Kγ and 9.1 nM for PI3Kδ. Additionally, it demonstrates antitumor activity.Formula:C22H20F2N6O4Color and Shape:SolidMolecular weight:470.43PI3K/HDAC-IN-1
CAS:PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).Formula:C22H25FN4O4Purity:98%Color and Shape:SolidMolecular weight:428.46mTOR inhibitor 9d
CAS:mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia,Formula:C21H23N5O3SPurity:98.90%Color and Shape:SoildMolecular weight:425.5IHMT-PI3K-455
IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor, demonstrating oral activity, with IC50 values of 7.1 nM for PI3Kγ and 0.57 nM forFormula:C26H21F2N7O3Purity:98%Color and Shape:SolidMolecular weight:517.49AZD-7648
CAS:AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.Formula:C18H20N8O2Purity:99.03% - 99.85%Color and Shape:SolidMolecular weight:380.4Ref: TM-T7122
1mg40.00€5mg88.00€10mg119.00€25mg187.00€50mg311.00€100mg472.00€200mg687.00€1mL*10mM (DMSO)87.00€
