Oligosaccharides

Fructononasaccharide is a modification of oligosaccharides that is synthesized from sucrose. It is a complex carbohydrate that has been modified with methylation and glycosylation. Fructononasaccharide is used in the synthesis of polysaccharides, as well as for the production of high-purity, custom-synthesized monosaccharides and disaccharides. Fructononasaccharide can be fluorinated or saccharified to produce different compounds.

Benzyl 4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-2,3-di-O-benzylb -D-galactopyranoside is a Fluorination and Glycosylation product. It is a Custom Synthesis of Monosaccharide and Oligosaccharide. The CAS number for this product is 106835-99-8.

Blood group B-HSA conjugate useful for raising antibodies

3-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactose is a synthetic compound that is synthesized by the reaction of 3,4,6-trihydroxypyranose with trifluoroacetic anhydride. The product can be purified to the desired level of purity using preparative HPLC or recrystallization. The CAS number for this compound is 97096-73-6.END>

Applications (-)-Sweroside is an active ingredient of iridoid glycoside isolated from the flower buds of Lonicera japonica THUNB. (-)-Sweroside has shown anti-inflammatory and analgesic activities. References Luo, Y., et. al.: Chem. Pharm. Bull., 57, 79 (2009); Keun, H., et. al.: Biosci. Biotech. Bioch., 74, 2022 (2010)

1,2,3-Tri-O-acetyl-5-O-benzoyl-4-C-fluoromethyl-D-ribofuranose is an organic compound. It is a triacetate of 5'-O-(4,6'-dichloroacetyl)-1,2,3:5',6'-tetraethylideneuridine and a fluorinated derivative of ribofuranose. The chemical formula for 1,2,3:5',6'-tetraethylideneuridine is C9H14F8N2O8 and the molecular weight is 498.17 g/mol.

Gala1-3(Fuca1-2)Galb1-3GlcNAcb1-3Gal (B antigen pentasaccharide Type I)

Applications Anthracycline antibiotic related to the rhodomycins. Antineoplastic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Yang, Z., et al.: J. Pharmacol. Experim. Ther., 327, 474 (2008), Zhao, Y., et al.: Int. J. Pharm., 379, 90 (2009), Bayne, W., et al.: J. Pharm. Sci., 98, 2540 (2009),

GT1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes. It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).

Metabolized by bacteria in the large intestine

2-Acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4-O-acetyl-6-O-(2,3,4,6-tetra-O-benzoyl-b-D -galactopyranosyl)-2 deoxy a D galactopyranosyl Fmoc threonine tert butyl ester is a custom synthesis with high purity and custom synthesis. This product is recommended for methylation and glycosylation reactions. It is a complex carbohydrate that has been modified by fluorination and saccharide.

Raffinose-sp-biotin is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. It is available in CAS No. and has the molecular formula C6H14O6. Raffinose-sp-biotin is a polysaccharide with a complex carbohydrate structure.

Used for studies of the D-lactose pathway by non-invasive techniques, using ¹â¹F-NMR spectroscopy or positron emission from the ¹âžF-labeled compound.

Applications A potent and selective inhibitor of NAE. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. The ubiquitin-proteasome pathway mediates the destruction of unwanted proteins. Potent NAE inhibitor; NEDD8 E1 Activating Enzyme Inhibitor. References Haas, A., et al.: J. Biol. Chem., 257, 10329 (1982), Walden, H., et al.: Nature, 422, 330 (2003), Kane, R., et al.: Clin. Cancer Res., 13, 5291 (2007), Saha, A., et al.: Mol. Cell., 32, 21 (2008),

Please enquire for more information about Difucosyl-para-lacto-N-hexaose III including the price, delivery time and more detailed product information at the technical inquiry form on this page

Drug carrier for cancer therapy & imaging, biocompatible, soluble, biodegradable

Rutinose is a naturally occurring polyphenol found in many plants, including the leaves and bark of rue plants. It is a glycoside derivative that has been shown to inhibit human colorectal adenocarcinoma cells (HL-60) by binding to DNA and inhibiting RNA synthesis. Rutinose also has been shown to have anti-inflammatory effects and has been used in the treatment of metabolic disorders such as diabetes mellitus. Rutinose is a bioactive compound with antioxidant properties that may be related to its ability to bind metal ions, including calcium ions at physiological pH levels. Rutinose also has been shown to have a signal peptide sequence that targets it for secretion into the blood stream, where it may act on brain functions.

Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This octasaccharide ammonium salt and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).

Raffinose is the most abundant of the family of oligosaccharides that are α-galactosyl derivatives of sucrose (Collins, 2006). The other main member of the group is the tetrasaccharide stachyose. Raffinose is found in sugar beet molasses and whole grains. Soybean oligosaccharides make up approximately 5% of dry matter in whole beans and up to 8% of dry matter in soybean meal. Together raffinose and stachyose rank second only to sucrose in abundance, as water-soluble carbohydrates (Kumar, 2010).

Stability Hygroscopic Applications Cyanidol 3-Glucoside is a anthocyanin that is naturally occurring in various fruits, vegetable and plants. Cyanidol 3-Glucoside is known to exhibit high antioxidant capacity and neuroprotective effects by triggering mobilization of cellular free sialic acid and utilizing it as an additional biological antioxidant in brain neural cells. References Damar, I., et al.: Food. Chem., 135, 2910 (2012); Kim, S.M., et al.: Life. Sci., 90, 874 (2012); Asada, T., et al.: J. Agri. Chem., 60, 10634 (2012);

This compound is a custom synthesis. It is an oligosaccharide, polysaccharide and modification of saccharides. The compound has been modified with methylation, glycosylation, and fluorination. This compound is a high purity product with the CAS number 93496-44-7.

This is a custom synthesis of a polysaccharide.

NGA3 N-Glycan is a high purity, custom synthesis, sugar-containing glycoprotein. It is synthesized by Click modification of the glycopeptide backbone with a fluorinated amino acid and then glycosylated with an acetylated sugar. The acetylation of the sugar allows for selective labeling of the glycan. This product can be used in research applications such as Fluorination, Glycosylation, Synthetic, Methylation, Modification and Carbohydrate. It has CAS No. 110387-63-8 and is available in both Monosaccharide and Oligosaccharide form.

Glycoside of Sialyl Lewis X

Stability Hygroscopic Applications Studies have shown this compound to have anti tumor effects. References Suzuki, K., et al.: Carbohydrate Research, 151, 403 (1986)

Mixed DP 25-50 Na galacturonans, (α-1,4 25-50 Na galacturonans) are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s). In recent studies, it has been shown that long oligogalacturonides (degree of polymerization (DP) from 25–50), help to induce plant defense signaling resulting in enhanced defenses to necrotrophic pathogens.

Applications Isotope labelled 1,5-Anhdyro-D-glucitol (A648000), a compound that has been isolated from several plant and animal sources, discovered in human cerebrospinal fluid and blood plasma and found to be an inhibitor of several enzymes. References Yamanouchi, T. et al. Am. J. Physiol. 263, E268 (1992); Yoshioka, S. et al. Clin. Chem. 30, 188, (1984); Field, R.A. et al. Bioorg. Med. Chem. Lett. 1, 667 (1991); Cavallaro, C.L. and Schartz, J. J. Org. Chem. 61, 3863 (1996).

Chondroitin sulphate octasaccharide ammonium salt is a synthetic, fluorinated glycosaminoglycan. It is a synthetic, fluorinated glycosaminoglycan that has been synthesized from chondroitin sulfate and 2-amino-2-deoxy-D-glucose. Chondroitin sulphate octasaccharide ammonium salt has the CAS number 93860-92-7. It can be modified to make it more complex, such as methylation or click modification to give it different properties. This product is offered in high purity with a custom synthesis service available on request.

2,3,6,2',3',6',2'',3'',4'',6''-Deca-O-acetyl-a-D-maltotriosyl bromide is an acetylated and fluorinated oligosaccharide that has been prepared by a click reaction. It can be used for the synthesis of glycosidic linkages in complex carbohydrates. This product is available as a custom synthesis.

Modulates bud dormancy in plants

3'-N-Glycolylneuraminyl-D-lactose sodium salt is a carbohydrate that has been modified by the addition of glycosylation, methylation and fluorination. It belongs to the group of complex carbohydrates and is a monosaccharide. 3'-N-Glycolylneuraminyl-D-lactose sodium salt can be used for the synthesis of oligosaccharides and polysaccharides, such as cellulose, chitin and glycogen. This product is high purity, custom synthesis and synthetic.

Please enquire for more information about a,a-D-Trehalose dihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Isolated from the products of the acid reversion of D-mannose

2-Acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4,6-di-O-acetyl-2,6 -deoxy--a-,D-,galactopyranosyl--Fmoc--L--threonine tert--but yl ester is a synthetic carbohydrate that contains 2 acetamido groups and 3 O-(2,3,4,6 tetra O acetyl b D galactopyranosyl) groups. The chemical name for this compound is 2 Acetamido 3 O (2 3 4 6 tetra O acetyl b D galactopyranosyl) 4 6 di O acetyl 2 deoxy a D galactopyranosyl Fmoc L threonine tert but yl ester. It has been synthesized by the Click modification reaction of an oligos

A short chain isomer of inulin

Methyl 6-O-[(3-O-b-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-galactopyranoside is a glycosylated, fluorinated, saccharide that can be custom synthesized. The CAS number for this compound is 127571-99-1. This product is a monosaccharide with a molecular weight of 576. Methyl 6-O-[(3-O-b-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-galactopyranoside has been used in Click modification and polysaccharide synthesis.

Applications An intermediate of 4-Methylumbelliferyl β-D-N,N',N”-Triacetylchitotrioside. References Yang, Y., et al.: J. Biochem., 87, 1003 (1980)

2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio-D-ribofuranose is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide with CAS No. and a Polysaccharide that has been modified by Methylation and Glycosylation. It is also a Modification of saccharide, which is a Carbohydrate that contains the sugar, glucose. The purity of 2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio--D--ribofuranose is high and it has been Fluorinated for Synthetic purposes.

Substrate for b-6-GlcNAc-transferase

A natural structural element in a variety of glycoconjugates, found in milk, urine, meconium and glyciproteins. Substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar and for characterizing lectins.

Neutral octasasaccharide naturally present in human breast milk

Applications Methyl 4-Deoxy-4-fluoro-α-D-glucose (cas# 56926-53-5) is a compound useful in organic synthesis.

Please enquire for more information about 6-Sialylgalacto-N-biosyl-serine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This tetrasaccharide ammonium salt and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).

A MurNAc disaccharide

Applications 5-Azido-6-(tert-butyldimethylsilyl)-2,3-O-isopropylidene L-Gulono-1,4-lactone (cas# 118464-49-6) is a compound useful in organic synthesis.

Hyaluronate fluorescein is a polymer of hyaluronic acid that has been modified with fluorescein. It is synthesized by the methylation and saccharide coupling of an oligosaccharide, followed by Click modification and the addition of a fluorescent dye. Hyaluronate fluorescein has a molecular weight of 2500kDa. It is highly purified and can be custom-synthesized to suit specific needs.

Heparin disaccharide I-S, tetrasodium salt is a sodium salt of heparin that has been modified to contain two sulfate groups. The chemical modification of heparin disaccharide I-S, tetrasodium salt alters the molecule's charge and surface properties. This modification increases the molecule's ability to bind with cell surface markers and inhibits the activity of proteases. Heparin disaccharide I-S, tetrasodium salt is able to inhibit leukaemia proliferation in thp-1 cells by binding with cytoskeletal proteins such as vimentin and actin. This chemical also prevents PMA induced morphological changes in thp-1 cells. Heparin disaccharide I-S, tetrasodium salt is used as an anticoagulant in therapeutic settings. It is used to prevent blood clotting by inhibiting the activation of factors Xa and IIa. Heparin disaccharide

Neutral hexasasaccharide naturally present in human breast milk

Core antigen fragment in ABO blood group system

Drug carrier for cancer therapy & imaging, biocompatible, soluble, biodegradable

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Trifucosyl (1-2,1-2,1-3)-iso-lacto-N-octaose is a custom synthesis that is a complex carbohydrate. It is an oligosaccharide that contains three monosaccharides linked by alpha glycosidic bonds. This compound has been modified using methylation and glycosylation reactions. Trifucosyl (1-2,1-2,1-3)-iso-lacto-N-octaose has been fluorinated at the C6 position of the sugar ring to increase its solubility in water and enhance its stability in acid conditions. The product is a high purity synthetic compound.

2,3,6-Tri-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-[(2,3,4,6-tetra-O-acetyl bDgalactopyranosyl)]bDglucopyranosyl)-aDglucopyranosyldimethyl bromide is a synthetic sugar that is used as a building block for the synthesis of glycosides. This monosaccharide has been modified using click chemistry to obtain a methylated form that can be used in the synthesis of oligosaccharides and polysaccharides. It is also used to produce an acetal derivative that can be used in the synthesis of glycosidic linkages.

Starting material for semi-synthesis of N-glycans

GlcA[3S]b(1-3)Galb(1-4)GlcNAcb(1-2)Mana-Ethylazide is an oligosaccharide used in glycosylation and esterification reactions. It is a complex carbohydrate that consists of a methylated mannosamine backbone, with alpha-D-glucose and alpha-D-galactose units attached to the mannosamine. GlcA[3S]b(1-3)Galb(1-4)GlcNAcb(1-2)Mana-Ethylazide has a fluorinated ethyl group at the 3 position of the mannosamine, which can be modified with other reactive groups. The CAS number for this compound is 84726-43-7.

Methyl-O-b-D-glucopyranosyl-(1-3)-S-b-D-glucopyranosyl-(1-4)-O-4-thio-b-D-glucopyranosyl-(1,4)-b-D-[2] glucopyranoside is a synthetic saccharide with a single modification of 4'-fluoro substitution on the O6 position. This modification provides an increased stability to acid hydrolysis. Methylation and saccharide synthesis is performed in our lab and custom modifications are available upon request.

NGA4 N-glycan is a monosaccharide that is methylated and glycosylated to form an oligosaccharide. It has a molecular weight of 1205 g/mol. This product can be used in the production of glycoconjugates, which are used in the treatment of cancer and inflammatory diseases.

1,6-Anhydro-3-O-b-D-glucopyranosyl-b-D-glucopyranose is a glycosylation agent that is used in the synthesis of complex carbohydrates. It has been modified by methylation, click modification, and fluorination to produce 1,6 anhydro-3-[2-(N′-[1-(4-chlorophenyl)ethylidene]amino)-2-(N′-[1-(4-chlorophenyl)ethylidene]amino)]ethylidene]-b -D glucopyranoside. This product is CAS No. 60932-82-7 and can be custom synthesized to produce high purity and low impurities.

Chondroitin sulphate hexasaccharide ammonium salt is a synthetic glycoconjugate that is used as a drug for the treatment of osteoarthritis and other joint diseases. It is a complex carbohydrate consisting of glucuronic acid, galactose, N-acetylgalactosamine, and sulfate residues. Chondroitin sulphate hexasaccharide ammonium salt has high purity and can be custom synthesized to your specifications. This product is methylated with an acetyl group at carbon 6. The monosaccharides are modified by glycosylation with glucose or mannose residues. Chondroitin sulphate hexasaccharide ammonium salt has been click-modified to include a carboxylic acid moiety on the primary amine group at carbon 2 and an amino group on the terminal amino group at carbon 3.

Maltotriose hydrate is a synthetic glycosylation product that is synthesized by the fluorination of maltotriose. Maltotriose hydrate is a sugar with a 3-D structure that is similar to maltodextrin, but with one less glucose residue. Maltotriose hydrate can be used in the synthesis of oligosaccharides and polysaccharides and has been shown to have high purity. Maltotriose hydrate can be modified by a variety of reactions, such as methylation, monosaccharide modification, or click chemistry. It has an CAS number and can be custom synthesized for clients' needs.

Computational fluid dynamics (CFD) is the study of fluid flow, a subject which has been studied for over two thousand years. The idea of CFD is to use computers to solve the equations that govern fluid flow and to make predictions about the behavior of gases, liquids and complex fluids in various situations. Computational analysis can be used to calculate how air flows around an object such as a car or plane. This allows engineers to create designs with less drag. Computational analysis can also be used in designing buildings, bridges, and other structures that are exposed to large amounts of wind. CFD is a "convective" computational method because it solves problems by using convection-diffusion equations with appropriate boundary conditions. A "transport" computational method solves problems by solving momentum equations and energy conservation equations simultaneously; this method is often more accurate than convective methods but computationally more expensive. A "laminar" computational method solves problems by solving continuity equations. A "nature

Galactosyl isomaltol is a sugar molecule that is produced by the enzymatic hydrolysis of lactose. It has been shown to have antimicrobial activity against human pathogens and can be used as an antioxidant. Galactosyl isomaltol binds to lysine residues on bacterial cell walls, preventing the formation of new cells and causing cell death by interfering with protein synthesis. The addition of galactosyl isomaltol to food decreases the levels of phycocyanin, which are a type of fluorescent pigment found in blue green algae. This compound also has magnetic resonance analysis properties that could be used for diagnosis.

Hyaluronate fluorescein is a fluorinated carbohydrate that has been modified for use in the detection of methylation. It contains an oligosaccharide and polysaccharide that are attached to a 20kDa fluorinated saccharide. This product is available in high purity and is custom synthesized for your specific needs.

ABO trisaccharide immobilised on Fractogel with glycosylamine formation