Dyes and metabolites

Applications The Fluorescein Arsenical Hairpin Binder (FlAsH) method is presented for fluorescence labeling of proteins in living cells. Labeling proteins with the membrane-permeant fluorogenic biarsenical dye fluorescein arsenical hairpin binder-ethanedithiol (FlAsH-EDT2). The membrane-permeant fluorogenic biarsenicals FlAsH-EDT2 and ReAsH-EDT2 can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and resorufin. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gaietta, G., et al.: Science, 296, 503 (2002), Hoffmann, C., et al.: Nature Methods, 2, 171 (2005), Dyachok, O., et al.: Nature, 439, 349 (2006), Gautier, A., et al.: Chem. Biol., 15, 128 (2008),

Applications Solvent Blue 104 (cas# 116-75-6) is a useful research chemical.

Applications Auramine O is a substituted diphenyl-methane cationic dye. Auramine O has been used as a probe for studies of microheterogeneous systems, from micelles, proteins, polymers to silica surfaces. Dyes and metabolites, Environmental Testing. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Ferreira, A.U.C., et al.: J. Lumin., 136, 63 (2012)

Stability Light Sensitive Applications Disperse Polyester Dark Blue causes photocontact dermatitis in workers engaged in its manufacturing. References Davies, Keith A., et al.: J. Appl. Chem. Biotechn., 25(3), 195-204 (1975)

Applications A red Cy3-based biarsenical fluorescent probe targeted to a complementary binding peptide. AsCy3 has good photostability, low pH sensitivity, high absorbance, and good quantum yield. This new probe provides a FRET partner to biarsenical dye FlAsH, making this discovery an important step toward a whole toolkit of colored probes directed to different small peptide motifs. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cao, H., et al.: J. Am. Chem. Soc., 129, 8672 (2007)

Applications A reagent used to synthesize various dyes used in the textile industry. This is the labeled analog. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Rosenkranz, H.S. et al.: Mutagen., 5, 137 (1990);

Stability Moisture Sensitive Applications Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens. Dyes and metabolites. References Riggs, H.J.L., et al.: Amer. J. Pathol., 34, 1081 (1958), Mann, K.G. and Fish, W.W., Methods in Enz., 26, 28 (1972),

Applications Mono N-Desmethyl Disperse Polyester Dark Blue is a disperse dye for synthetic polyester fibers. It has good heat and light resistance and is used for thermal transfer recording. References Peters A. T., et al.: J. Soc. Dyers Colour, 108(7-8), 344-8 (1992)

Stability Light Sensitive Applications Chlorophyll A is a photosynthetic pigment that is essential for photosynthesis of eukaryotes and cyanobacteria, acting as a primary donor in the electron transport chain. Dyes and metabolites. References Prasad, K., et al.: Curr. Res. Chem., 3, 98 (2011); Shanab, S.M., et al.: Int. J. Electrochem. Sci., 6, 3017 (2011); Ajayan, K.V., et al.: Biores. Techol., 102, 7591 (2011); Felming, I.: Nature, 216, 151 (1967); Woodward, R.B. et al.: Tetrahedron, 46, 7599 1990); Chen, M. et al.: Sciemce, 319, 1318 (2010); Gitelson, A.A. et al.: Rem. Sens. Environ., 69, 296 (1999);

Applications Anthracene is obtained from coal tar. It is an important source of many dyes.This compound is a contaminant of emerging concern (CECs) Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities. References Peng, D. et al.: Chinese Med., 7, 2 (2012); Endale, M. et al.: Med. Inflamm., 748964/1 (2014);

Applications Isotope labelled 2-Toluidine (T536205) is a carcinogenic and toxic aromatic amine and is a potential bladder cancer risk, surmised from urine assessment and analysis (1). It is contained in hair dye, henna and dyed hair samples (2,3). Possible mutagen (4). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References 1. El-Bayoumy, K. et al.: Cancer Res. 1986 Dec;46(12 Pt 1):6064-7.2. Turesky R. et al.: Chem. Res. Toxicol. 2003 Sep;16(9):1162-73.3. Andrew, A. et al.: Int. J. Cancer. 2004 Apr 20;109(4):581-6.4. Kirkland, D. et al.: Mutat. Res. 2005 Dec 30;588(2):88-105.

Stability Hygroscopic, Light Sensitive Applications Basic Blue 26 is a basic dye used in a variety of applications and industries, including the cosmetic industry where it is found in temporary hair dyes. Basic Blue 26 adsorbs well to activated carbon surfaces. References Williams, T. N.; et al.: ACS Sustainable Chem. Eng., 6, 2344 (2018); Vieira de Souza, T. N.; et al.: Appl. Surf. Sci., 448, 662 (2018).

Applications Fluorescent Brightener KSN (cas# 5242-49-9) is a useful research chemical.

Stability Light Sensitive Applications Acrylamide-d3 is deuterium labeled Acrylamide (A191300). Acrylamide is a chemical intermediate in production of polyacrylamides that are use in protein electrophoresis (PAGE), synthesis of dyes and copolymers for contact lenses. It is reasonably anticipated to be a human carcinogen (1,2). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References (1) Mottram, D.S., et al.: Nature, 419, 448 (2002)(2) Tareke, E., et al.: J. Agric. Food Chem., 50, 4998 (2002)

Applications It is listed as a known human carcinogen. Used in manufacturing of dyes, as antioxidant in rubber. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Dong, Y., et al.: Bioorg. Med. Chem. Lett., 20, 4085 (2010), Vassiltsova, O., et al.: J. Nanosci. Nanotechnol., 10, 1635 (2010), Garcia-Lavandeira, J., et al.: Anal. Bioanal. Chem., 397, 751 (2010),

Stability Hygroscopic Applications 3-[N-(2-Carboxyethyl)methylamino]-7-[N-ethyl(3-sulfonatopropyl)amino]phenoxazin-5-ium sodium is a fluorescent dye for covalent labeling.

Applications A cell-permeable fluorescent probe selective for Zinc. Fluorescence: max. Em. l = 515nm References Koh, J., et al.: Science, 272, 1013 (1996), Suh, S., et al.: Brain Res., 852, 268 (2000), Finney, L., et al.: Science, 300, 931 (2003), Lopantsev, V., et al.: Neuroscience, 116, 237 (2003), Kambe, T., et al.: Cell Mol. Life Sci., 61, 49 (2004),

Stability Light Sensitive Applications Anti-infective (topical). Has been used as anthelmintic (Nematodes). Dyes and metabolites, Environmental Testing. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Hodge, H.C., et al.: Toxicol. Appl. Pharmacol., 22, 1 (1972), Docampo, R., et al.: Drug Metab. Rev., 22, 161 (1990),

Applications Isotope labelled 24 Bisphenol S (B519620) is a material used in thermal printing. 24 Bisphenol S is also used in the development of black leuco dyes. References Shima, H. et al.: J. Imag. Sci. Technol., 54, 020502 (2010)

Stability Hygroscopic, Moisture Sensitive Applications Used as insect chemosterilant; in dyeing. Antineoplastic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gaines, et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969), Huitema, A., et al.: Br. J. Clin. Pharmacol., 51, 61 (2001), Jinno, H., et al.: Drug Metab. Dispos., 31, 398 (2003),

Applications 3,4,9,10-Perylenetetracarboxylic diimide (cas# 81-33-4) is a useful research chemical.

Applications Carcinogenic compound commonly found in hair dyes and henna ink, also a commonly used synthetic intermediate Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Mulyono; T., et al.: J. Biosci. Bioeng., 103, 147 (2007), Mosley-Foreman, C., et al.: Food Chem. Toxicol., 46, 3780 (2008), Patel, A.K., et al.: J. Agric. Food Chem., 56, 9236 (2008), Akyuz, M., et al.: J. Pharm. Biomed. Anal., 47, 68 (2008),