Polycyclic Compounds

Please enquire for more information about Methyl 4-bromo-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Isoquinoline-5-carboxylic acid is a thiourea that can be synthesized from acetone and trifluoromethyl iodide. It emits red light when irradiated with light, which makes it a good candidate for use in LEDs. The emission intensity can be controlled by varying the pH of the solution. Isoquinoline-5-carboxylic acid has been used to create ancillary ligands for metal complexes, such as iridium complexes. These ligands are used to measure oxidation states and electron transfer rates in electrochemistry experiments.

Please enquire for more information about 2-Chloro-N-[1-(2-furoyl)-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylacetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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1-Methyl-3,4-bis(3-indolyl)maleimide (1M3BM) is a chemical compound that has been shown to be an inhibitor of the epidermal growth factor receptor. It binds to the EGF receptor, thereby preventing the binding of EGF and activation of downstream signaling pathways. 1M3BM inhibits the activity of enzymes that synthesize fatty acids in cells, which may lead to decreased fat accumulation in fat cells. This drug also inhibits the activation of toll-like receptors by blocking nuclear factor κB (NFκB). These effects may help to alleviate diabetic neuropathy.

Please enquire for more information about 1-(9,9-Dimethyl-9H-fluoren-2-yl)-isoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5-Bromo-3-methyl-1H-indazole is an organic compound that is synthesized from lithium diisopropylamide and lithium. 5-Bromo-3-methyl-1H-indazole is a white solid with a melting point of 151°C. It reacts with anhydrous hydrogen bromide to form 5,5'-dibromoindazole. The molecular weight of this compound is 202.2 g/mol.

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(S)-(-)-3-Aminoquinuclidine 2HCl is a cholinergic agonist that has been shown to be effective in inducing the release of acetylcholine from brain synaptosomes. This drug binds to the nicotinic acetylcholine receptor (nAChR) and inhibits the action of the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine in the synaptic cleft. The drug is also able to cross the blood-brain barrier and bind to receptors on neurons. It has been shown that this drug can be used as an imaging agent for molecular magnetic resonance tomography (MRT), with high sensitivity and specificity.

7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide is a molecule that has been shown to activate the AMPK pathway and inhibit the mTOR pathway. It has been shown to decrease the growth of cancer cells in vitro and in vivo. The drug also has an effect on physiological function by regulating protein synthesis. 7APECC has proven to be effective against breast cancer cell lines MDA-MB231 and MCF7 (PDL1) as well as mesenteric adipocytes (Dinucleotide phosphate).

Please enquire for more information about 2-(4-Aminophenyl)hexahydro-1H-isoindole-1,3(2H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3,5-Dichloro-6-methyl-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Lactone

6-Fluoroindole-3-carboxaldehyde (6FLA) is a synthetic compound that inhibits biosynthesis of the phytoalexins salicylic acid and lignin in plants. It also inhibits the β-glucuronidase enzyme, which hydrolyzes the glucuronide conjugates of phenolic compounds and xenobiotics. 6FLA has been shown to cause mild liver damage in rats, but its effects on humans are unknown. 6FLA may be used as a detectable substance for assays.

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Indoline-5-carboxylic acid is a fluorinated indole. It has been shown to be an effective cancer treatment, with a potency at least equivalent to that of oxindole. Indoline-5-carboxylic acid also inhibits the production of an enzyme in the brain, which is thought to be responsible for Alzheimer's disease. This compound also interacts with aldehydes and ligands, as well as chlorine atoms. Indoline-5-carboxylic acid can be synthesized by a number of different techniques, including Wolff-Kishner reduction and chlorination reactions. The physicochemical properties of this molecule are not well known at this time.

Applications octahydro-1H-indole-2-carboxamide (cas# 1105694-34-5) is a useful research chemical.

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Please enquire for more information about (3S,4AS,8aS)-2-((2R)-2-((4S)-4,5-dihydro-2-(3-hydroxy-2-methylphenyl)-4-oxazolyl)-2-hydroxyethyl)-N-(1,1-dimethylethyl)decahydro-3-i soquinolinecarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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4-Nitroquinoline-N-oxide is a polymerase chain reaction (PCR) inhibitor that blocks the activity of methyltransferases, which are enzymes involved in DNA replication and repair. The mechanism of action has been shown to be due to the inhibition of the activities of these enzymes in cancer tissues. The efficacy of 4-Nitroquinoline-N-oxide has been demonstrated using an experimental model system composed of cells from Candida glabrata and other cancers, as well as a model system for carcinogenesis in vitro. This compound also shows antiinflammatory activity and can be used as a natural compound for chemotherapy. Chromatographic analysis has revealed that 4-Nitroquinoline-N-oxide is not toxic to wild type strains, but it is toxic to cancer cells with mutations in their DNA repair mechanisms.

Please enquire for more information about 2,3-Dimethyl-1h-indole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (1S,3R,4S)-Quinuclidin-3-yl (2-benzoylphenethyl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 4'-Bromo-2,2':6',2''-terpyridine (cas# 149817-62-9) is a useful research chemical.

Applications 8,8-dimethyl-2-oxabicyclo[4.2.0]octan-7-amine (cas# 1342540-54-8) is a useful research chemical.

2-Oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid is a carboxylic acid that is an intermediate in the chemical synthesis of 2H and 3H tetrahydroquinolines. It can be synthesized by the oxidation of 2-(N,N-dimethylamino)benzaldehyde with hydrogen peroxide in methanol. The compound has been used to label animals for use in mass spectrometry studies and as a reactant in electron and nuclear magnetic resonance (NMR) spectroscopy experiments. In addition, 2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid has been used to study equilibrium and reversible reactions as well as to identify the abundances of different spectral peaks. 2-Oxo-1,2,3,4-tetrahydroquinoline-4

Lactone

Please enquire for more information about tert-Butyl 5-hydroxy-1H-indole-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Scopoletin exhibits antifungal, anti-allergic, anti-aging, and hypouricemic activities, it exerts anti-RA action probably through suppressing IL-6 production from fibroblast-like synoviocytes via MAPK/PKC/CREB pathways. Scopoletin can ameliorate alcohol-induced hepatic lipid accumulation by modulating AMPK-SREBP pathway-mediated lipogenesis in mice fed a high-fat diet.

Please enquire for more information about 2-(2,4-Dimethylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Bromoisoquinoline is a bifunctional alkylating agent that is used to synthesize esters and amides. It is commonly used for the synthesis of amino acids, peptides, and other biologically active molecules. 8-Bromoisoquinoline has been shown to have a synergistic effect with hydroxyalkyl carbamates, which may be due to its ability to form an ionic bond with the carboxylic acid in these compounds. This chemical can also react with nitro groups and serve as a chlorinating agent, as well as react with anions such as phosphate and acetate. 8-Bromoisoquinoline can be synthesized by reacting ethyl bromoacetate with tetrahydroisoquinolinium chloride in hydrochloric acid or isopropyl alcohol.

5-Methoxyindole is a chemical compound that is soluble in water. It has been shown to inhibit tumor growth and induce apoptosis, as well as inhibit the expression of glycogen synthase kinase-3. The structure of 5-methoxyindole was determined by NMR spectroscopy and FT-IR spectroscopy. The compound has been observed to exhibit fluorescence properties at a wavelength of 490 nm when it is excited with UV light. A copper complex of 5-methoxyindole was studied using molecular modeling and FT-IR spectroscopy, which revealed that it can undergo nucleophilic attack by hydrogen bond formation or an acid/base reaction to form a new hydrogen bond. This study also found that 5-methoxyindole is able to form hydrogen bonds with its neighboring molecules, which may contribute to its high solubility in water.

1-(2,3-Dihydroxypropyl)-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione (theophylline) is a bronchodilator and anti-inflammatory agent. It is used to treat asthma and other respiratory conditions. Theophylline is structurally similar to caffeine and theobromine and has been shown to have a similar effect on the heart and blood vessels as these stimulants. It also stimulates the central nervous system in a manner similar to that of theobromine. Theophylline has shown some benefit in congestive heart failure patients but has not been proven effective for treating high blood pressure or fibrillation.

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Lactone

Please enquire for more information about Ethyl 7-cyclopropyl-1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about (4,4,6,8-Tetramethyl-2-oxo-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1(2H)-ylidene)malononitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5-Chloro-1,10-phenanthroline (5CP) is a molecule that has been used in the study of DNA oxidation. 5CP has been shown to be an effective inhibitor of oxidative dna damage and can be used for the prevention of mutations caused by reactive oxygen species. This compound was also found to inhibit the growth of L1210 murine leukemia cells, which is due to its ability to bind to potassium ions. 5CP has been shown to have significant binding constants with DNA and protein molecules. It also has a very high level of ancillary activity and can be used as a catalyst in transfer reactions.

Please enquire for more information about 9-Benzyl-3-oxa-9-azabicyclo[3.3.1]nonan-7-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

6,7-Dihydro-5H-isoquinolin-8-one is a chemical substance that belongs to the group of azomethine and aporphine alkaloids. It has been isolated from plants of the genus Liriodendron. This compound is used as a precursor in organic synthesis and as an intermediate in the preparation of liriodenine, lanuginosine, norcorydine and other related compounds. 6,7-Dihydro-5H-isoquinolin-8-one has been shown to have antiinflammatory properties due to its ability to inhibit prostaglandin synthesis. This substance has also been used as an insecticide or acaricide.

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Oxypeucedanin is a major coumarin aglycone that can be extracted from Ostericum koreanum, coumarin aglycones have demonstrated various pharmacological effects, including anti-proliferation, anti-inflammation, and anti-pain; based on transcriptional alteration and complicated modulation of MAPK signaling, might be underlying mechanisms responsible for the various pharmacological effects of oxypeucedanin.

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6-Aminoquinoline-5-carbonitrile is a nitro compound that is synthesized from 6-nitroquinoline and 1-nitropropane. The reaction proceeds with the elimination of nitrogen gas to produce the expected product, 6-aminoquinoline-5-carbonitrile. The synthesis of this compound begins with the reaction of 6-nitroquinoline and 1-nitropropane in dimethyl sulfoxide solution. Nitrogen oxide is produced as a byproduct, which can be eliminated with heat to yield a mixture of nitroethane and nitroacetate. Nitrogen reacts with these compounds to form the desired product.

Please enquire for more information about Isoquinoline-5-boronic acid HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 6-[N,N-Di(2-hydroxybenzyl)amino]-2-[(3-hydroxypropyl)amino]-9-isopropylpurine (cas# 1076200-04-8) is a compound useful in organic synthesis.

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Oxypeucedanin is a furanocoumarin compound, which is derived from various plant sources, most notably those in the Apiaceae family such as Peucedanum and Angelica species. It functions primarily as a photoreactive agent, capable of interacting with DNA under ultraviolet (UV) light through a process called photoactivation. Upon UV exposure, it forms covalent bonds with DNA, leading to cross-linking that can disrupt cellular functions. The biological activities of Oxypeucedanin make it relevant in a range of scientific research and potential therapeutic applications. It has been reported to exhibit antioxidant, anti-inflammatory, and antimicrobial properties, offering interest for further studies in pharmacology. Moreover, due to its DNA-interacting capabilities, it is a subject of research in photochemotherapy, particularly for skin conditions such as psoriasis and vitiligo. As with many such compounds, careful consideration of its effects and toxicological profile is critical in the exploration of its applications. Oxypeucedanin continues to be a topic of scientific investigation, exploring its multifaceted roles and potential benefits in human health and disease management.

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