Polycyclic Compounds

Please enquire for more information about 2-(4-Bromophenyl)-6,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Methyl Oxindole-6-carboxylate is an intermediate used to prepare BIBF 1120, an indolinone as triple angiokinase inhibitors. References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009)

Please enquire for more information about [3S-(3S,4aS,8aS,2'R,3'R)]-2-[3'-Amino-2'-hydroxy-4'-(phenyl)thio]butyldecahydroisoquinoline-3-N-t-butylcarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Oxo-5-[[(2S)-1-oxo-1-[[2-oxo-4-(trifluoromethyl)-1H-quinolin-7-yl]amino]-3phenylpropan-2-yl]amino]pentanoic acid (AFPC) is a fluorescent substrate used to measure the kinetics of chymotrypsin. The fluorescence intensity increases with the increase in the concentration of AFPC, indicating that the reaction is occurring at an increasing rate. AFPC is a fluorogenic substrate for chymotrypsin and can be used as a marker for enzyme activity. It displays high sensitivity and fast kinetics, which makes it suitable for use in kinetic assays.

Please enquire for more information about 2-(9,9-Dimethyl-9-h-floren-2-yl)quinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Gatifloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Gatifloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Gatifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

3-Methyl-2-chloro-3H-imidazo[4,5-f]quinoline is a synthetic organic compound that has been used as a research tool. The compound features an imidazole ring with a methyl and chloro substituent at the 3 and 2 positions respectively. It is soluble in alcohols and organic solvents such as acetonitrile. 3-Methyl-2-chloro-3H-imidazo[4,5-f]quinoline has been shown to induce cancer in laboratory animals and may be carcinogenic for humans. The mechanism of its carcinogenicity may be due to its ability to bind with DNA and form adducts, which inhibit DNA replication or repair.

Please enquire for more information about 2-(4-Ethylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-Oxo-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-13-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(2-(4-Bromophenyl)-6,6-dimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (1S,3S)-1,3-Diallyl-1,2,3,4-tetrahydroisoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Nitrobenzyl (4R,5R,6S)-3-[(diphenylphosphono)oxy]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylat e is a synthetic compound that is used as an alkalizer and impurity scavenger in the manufacture of pesticides and other organic chemicals. It has been shown to be a stereoselective herbicide with acetonitrile as its primary degradation product. The compound has also been found to be a potent inhibitor of the enzyme carbapenemase, which may lead to increased resistance to antibiotics such as monosodium salt of ertapenem.

Please enquire for more information about 6-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page