Polycyclic Compounds

Please enquire for more information about Cyano(tricyclo[3.3.1.1~3,7~]dec-2-ylidene)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Methyl-7-azaindole is a pyrrole that contains one proton and one deuterium. 3-Methyl-7-azaindole has been shown to have an affinity for dopamine receptors, which may be due to the methyl groups on its aromatic ring. The deuterium isotope has been shown to affect the molecule's fluorescence properties. This molecule also has been shown to have antipsychotic effects in animal studies and can be used as a potential drug for schizophrenia treatment.

5-Benzyloxy-1H-indazole is a halogenated indazole that is both cyclized and acetoned. The compound has been shown to be active against bacteria, including Mycobacterium tuberculosis. This compound's mechanism of action is not yet known.

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4-Nitro-1H-indole-3-carbaldehyde is a molecule that has been synthesized for use in the field of crystallography. The compound is a diffraction and fluorescence probe that has been shown to enhance the fluorescence of spirolactam. 4-Nitro-1H-indole-3-carbaldehyde was synthesized by reacting 1,4 nitrobenzene with indole in the presence of potassium carbonate. This reaction yielded an 80% yield and a melting point of 210°C. 4NICA can be used as a ligand to study the physicochemical properties of other molecules.

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6-Bromo-4-hydroxyquinoline is a synthetic compound that has been shown to inhibit the growth of cancer cells. The synthesis of 6-bromo-4-hydroxyquinoline is achieved by reacting 4,5,6,7-tetrabromoquinoline with hydroxylamine in the presence of a base. This process forms 6-bromo-4-hydroxyquinoline in high yield and purity. A number of studies have shown that 6-bromo-4-hydroxyquinoline inhibits tumor cell proliferation and induces apoptosis in vitro. It also exhibits antiangiogenic activity by inhibiting the PI3K/mTOR pathway and angiogenesis through the inhibition of VEGF production. 6 - bromo - 4 - hydroxy quinoline can be used as an effective chemotherapeutic agent for cancers such as breast cancer, melanoma, lung cancer, prostate cancer, and

5-Iodoisatin is a cross-coupling agent that has an inhibitory effect on tumor tissue. It is also used for the synthesis of conjugated drugs and pharmacological research. 5-Iodoisatin, which forms a ternary complex with copper and iodide, inhibits the growth of colorectal carcinoma cells by interfering with their DNA replication and protein production. 5-Iodoisatin can be converted to its active form through the formation of a ternary complex with copper and iodide ions. This inhibition is due to its ability to interact with DNA, RNA polymerase, and other proteins involved in transcription, translation, and replication processes. 5-Iodoisatin is metabolized through conjugation with glucuronic acid or sulfate in the liver; it binds to human mitochondrial DNA and can enter cells via passive diffusion. The carbonyl group in this drug may play an important role in its interaction with cancer cells.

Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation. References Khanna P., et al.: Biochemistry, 40, 1441 (2001);