Polycyclic Compounds

Please enquire for more information about 2-(4-Ethylphenyl)-3-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

6,7-Dimethoxyisoquinoline is an isoquinoline alkaloid that has shown antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Gram-negative bacteria such as Escherichia coli. It inhibits bacterial growth by preventing the formation of the ternary complex between GTPase, GTP and cAMP. 6,7-Dimethoxyisoquinoline also has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. This compound is derived from popowia (Populus) bark extract and is used in vitro studies on Popowia faecalis.

Rac1,2,3,4-tetrahydroisoquinoline-3-methanol is a synthetic inhibitor of Rac1. It has affinity for the active site and steric bulk that is similar to other Rac1 inhibitors. It is not stereoselective, but because it is chiral, it can be used in conjunction with other drugs that are also chiral. Rac1,2,3,4-tetrahydroisoquinoline-3-methanol binds to the enzyme in a directionally selective way and interacts with the sequence of the active site. The methyl ester group on rac 1,2,3,4-tetrahydroisoquinoline-3-methanol enhances its hydrophilicity and enantiomeric purity.

Please enquire for more information about 10,11-Dihydro-N-(2-hydroxyethyl)-N-methyl-5H-pyrido[2,3-c][2]benzazepine-10-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5,7-Difluoro-1H-indole is a metabolically stable, potent inhibitor of influenza A virus polymerase. It has been shown to be active in vivo against influenza A and B virus replication. The compound is undergoing clinical development for the treatment of influenza. 5,7-Difluoro-1H-indole inhibits the activity of the influenza virus polymerase by binding to the enzyme’s basic protein and blocking its active site. This prevents viral replication and can lead to therapeutic benefits in patients with influenza A or B infections.

3-Methyl-3,8-diaza-bicyclo[3.2.1]octane dihydrochloride is a high quality reagent that is useful as an intermediate in the synthesis of complex compounds and as a reagent for fine chemicals. 3-Methyl-3,8-diaza-bicyclo[3.2.1]octane dihydrochloride can be used as a versatile building block in the synthesis of speciality chemicals and research chemicals. It can also be used to synthesize a variety of reaction components, such as amines, carboxylic acids, alcohols, amides, and nitriles.

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Applications Ethyl 6-Cyano-1H-indole-2-carboxylate is a chemical reagent used in the synthesis of benzofuran inhibitors for mitogen-activated protein kinase phosphatase-1. Applications towards diabetes, obesity and insulin-resistant metabolic disorders. Also a reagent in the preparation of platelet receptor glycoprotein (Gp) IIb/IIIa antagonists used as ati-thrombotic agents. References Lazo, J. et al.: Bioorg. Med. Chem., 14, 5643 (2006); Ono, S. et al.: Chem. Pharm. Bull.,

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The tetrahydropyran is an organic compound with the molecular formula CH3CH2CH2C(O)CH2OH. It is a colorless liquid that is soluble in water and polar organic solvents. The compound can be prepared by reacting acetonitrile with trimethyl borate: The reaction products of this process are among other things, 1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic acid methyl ester (DETPA). DETPA has been used as a neutralizing agent in the treatment of textile dyeing effluents and as a flow rate controller in metering pumps. Biological properties of DETPA include antipyretic properties and acid catalytic activity. One of the impurities found in DETPA is 3-(2'-hydroxyethoxy)propionic acid which can be removed by treatment