Polycyclic Compounds

Fluoropyridoxal is an intermediate in the metabolism of tryptophan, which is converted to 6-fluoropyridoxal phosphate. It has been used as a model system for studying the kinetics and mechanism of reaction of carboxylates with phosphites. Fluoropyridoxal reacts with phosphite to form two tautomers: one predominately in the cytosol and one predominately in the mitochondria. Magnetic resonance spectroscopy has been used to study fluoropyridoxal derivatives that are fluorescent, including 6-fluoropyridoxal phosphate. The synthesis of a polymer conjugate containing fluorine was also studied using fluoropyridoxal as a precursor.

Please enquire for more information about 2-(4-tert-Butylphenyl)-6-ethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-tert-Butylphenyl)-6-ethylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Fluoroindole-3-acetic acid is a molecule that has been synthesized by the reaction of 6-fluoroindole with acetic anhydride. When mixed with acetonitrile, the fluorescence of 6-fluoroindole-3-acetic acid can be seen in the solution. The fluorescence intensity is proportional to the concentration of this molecule. 6-Fluoroindole-3-acetic acid is used as a template molecule for fluorescence labeling experiments. It interacts with hormones and can be used to identify their conformations and interactions. This compound has been shown to have anticancer properties in mice, and it may also be effective against cancer cells in humans. It has also been shown to inhibit the growth of pisum sativum (pea).

2,2'-Bi(tricyclo[3.3.1.1~3,7~]decane) is a molecule that contains three fused cycloalkanes and two bridging carboxyl groups. It has a vibrational frequency of 1701 cm-1 and exhibits a Raman spectrum with peaks at 1460 cm-1 and 1590 cm-1. The 2,2'-bi(tricyclo[3.3.1.1~3,7~]decane) molecule is composed of six axial methyl groups (-CH 3 ) and four equatorial methyl groups (-CH 3 ). The axial methyl group on the left in the first ring has an average bond length of 1.446Å while the other five axial methyl groups have an average bond length of 1.416Å Theory suggests that this molecule can be formed from camphene (a bicyclic monoterpene hydrocarbon)

Please enquire for more information about Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-2-(3-hydroxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromo-1,1,2-trimethyl-1H-benzo[e]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Sodium 2,3,3-triMethyl-3H-indole-5-sulfonate including the price, delivery time and more detailed product information at the technical inquiry form on this page

7-(Bromomethyl)-6-Fluorobenzo[b]Phenanthrene is a chemical that has been shown to react with mouse skin. It can induce carcinogenesis in mice, and it reacts with the skin of mice to form papilloma. 7-(Bromomethyl)-6-Fluorobenzo[b]Phenanthrene is also used to react with other chemicals to form new compounds.

Please enquire for more information about 7-Chloro-2-(4-chlorophenyl)-8-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1,3-Dioxo-2-phenylisoindoline-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(4-Methoxybenzyl)-1H-indole-2,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Chloro-1H-indole-2-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Scoparone is a bioactive natural compound, which is primarily derived from plants in the Rutaceae family, such as Artemisia species. It is a coumarin derivative, known for its therapeutic properties due to its diverse biological activities. The mode of action of scoparone is multifaceted, involving the modulation of various enzymes and signaling pathways. It acts as an inhibitor of cytochrome P450 enzymes and influences pathways involving nitric oxide and reactive oxygen species, contributing to its anti-inflammatory and hepatoprotective effects. Scoparone's uses and applications are extensive in the fields of pharmacology and biochemistry. It is actively researched for its potential in treating liver-related disorders, such as hepatic fibrosis and jaundice, due to its ability to modulate enzyme activity and reduce oxidative stress. Additionally, scoparone exhibits significant anti-inflammatory and antioxidant properties, making it a topic of interest for treating conditions characterized by excessive inflammation. Furthermore, its role as a model compound for studying coumarin derivatives enhances its value in scientific research, expanding its relevance beyond purely therapeutic applications.

6-Bromo-2-chloroquinoline-3-carboxaldehyde is a potent antioxidant that scavenges reactive oxygen species. It has been shown to inhibit the formation of carbinols and amines and to cleave bonds in the skeleton of quinolones. 6-Bromo-2-chloroquinoline-3-carboxaldehyde has been used as a starting material for industrial preparation of antibacterial agents, such as antitubercular activity. This drug has also shown antidiabetic properties, which may be due to its ability to inhibit the production of glucose by the enzyme glycogen synthase kinase 3 beta (GSK3β). 6-Bromo-2-chloroquinoline 3 carboxaldehyde is an enantiomeric mixture with two stereoisomers: (R)-6-(bromomethyl) 2 chloroquine and (S)-6-(bromomethyl) 2 chloroquine. The

Please enquire for more information about 6-Chloro-2-(2-propoxyphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Hypoxanthine is a nucleoside that is found in human cells. It is synthesized from guanine by the enzyme, xanthine oxidoreductase. Hypoxanthine is also produced from xanthine by adenosine deaminase and converted back to xanthine, which can then be reused for DNA synthesis. Hypoxanthine has been shown to inhibit the growth of photosynthetic bacteria, such as Rhodopseudomonas viridis and Rhodobacter sphaeroides. This inhibition may be due to an equilibrative nucleotide effect on the folate receptor. The x-ray diffraction data collected from the chrysanthemum flower (a source of hypoxanthine) showed that hypoxanthine has a calcium salt structure.

Please enquire for more information about 4-Chloro-7-azaindole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromo-4-methoxyindole including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,3,3-Trimethyl-3H-benzo[e]indole is a reactive molecule that has been shown to be an effective treatment for cervical cancer. It can be used in conjunction with monoclonal antibodies that have been designed to target the acidic protonation sites on the surface of cervical cancer cells. This active form binds to the site and emits fluorescence when illuminated with a laser, which can then be detected by a confocal microscope. This technique can also be used for the diagnosis of other cancers. 2,3,3-Trimethyl-3H-benzo[e]indole is not toxic to human serum as it does not react with this type of tissue.

Please enquire for more information about 4-Hyrdroxy-6-iodoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 2-(chloromethyl)-4-oxo-4,9a-dihydro-1H-pyrido[1,2-a]pyrimidine-7-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Ethyl-2-(2-methylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Hydroxyindole-2-carboxylic acid is a metabolite of tryptophan. It can be found in the urine and blood of humans, as well as in some foods, such as beans. 6-Hydroxyindole-2-carboxylic acid oxidizes to form indoleacetic acid, which is used in the production of fluoroquinolones. The reductase gene that encodes for this enzyme has been cloned and expressed in E. coli. 6HICA is converted to quinolinecarboxylic acid by carboxylase enzymes and monooxygenases (e.g., cytochrome P450) before being excreted or further metabolized to indole-5-carboxylic acid by putidaredoxin or oxidized to form indoleacetic acid by cytochrome P450 enzymes. 6HICA may also be used as an assay for cytochrome

Please enquire for more information about 4-Bromo-2,5-dimethyl-2H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride is a chemical compound that inhibits the activity of parp1 (poly(ADP-ribose) polymerase 1). Parp1 is an enzyme that is involved in the repair and regulation of DNA. 2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride has been shown to be effective in the treatment of cancer and also inhibits the growth of bacteria. This drug also reacts with alkyl groups and substituents to form chains.

Please enquire for more information about 2-(4-tert-Butylphenyl)-8-methylquinoline-4-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Methoxy-1-methyl-1H-indole-3-carbaldehyde is a synthetic compound that has been shown to inhibit the growth of human tumour cells in vitro. This compound is a regioisomeric mixture of two enantiomers, with the (S) isomer being the more potent inhibitor. The (R) isomer was found to be less active against human tumour cells and may have an antimicrobial activity. 5-Methoxy-1-methyl-1H-indole-3-carbaldehyde has been shown to be bioreductive towards electron donors such as NADPH and glutathione. It also inhibits dt diaphorase and aerobic metabolism in human tumour cells.

Also called Skatole.  It occurs naturally in the feces of mammals and birds and is the primary contributor to fecal odour.

3-[(1S,2S,5R)-7-Oxo-3-thia-6,8-diazabicyclo[3.3.0]oct-2-yl]propanoic acid is a fluorescence detector that can be used to detect the presence of biotin in urine or other biological samples. It has been shown to bind with high affinity and specificity to bisnorbiotin, an analog of biotin. 3-[(1S,2S,5R)-7-Oxo-3-thia-6,8-diazabicyclo[3.3.0]oct-2-yl]propanoic acid is a pharmacologic agent that has been shown to inhibit human serum albumin polymerase chain reaction (PCR) amplification in vitro and in vivo. The biological properties of this compound are not well understood because it has only been tested in humans who have chronic oral intake of 3-[(

Please enquire for more information about 1-(Chloroacetyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about rac 4-hydroxy 3,4-dihydro-1(2H)-isoquinolinone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(2-Chlorobenzyl)-4-hydroxyquinolin-2(1H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Chloroquinolin-2-amine is a noncatalytic, palladium-catalyzed process for the synthesis of amines from 2-chloroquinoline and adamantane. This reaction results in the substitution of the chloro group on the 2-chloroquinoline with an amino group. The yield for this reaction is high, however it does not work with other substituents on the 2-chloroquinoline. 4-Chloroquinolin-2-amine can be used in reactions that require amines without substituents such as amination or arylation.

Please enquire for more information about 6-Chloro-3-methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1H-Indole-5-carbaldehyde oxime including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about [(8-Methylquinolin-5-yl)methyl]amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Boc-3-Hydroxymethyl-5-methylindole including the price, delivery time and more detailed product information at the technical inquiry form on this page

7-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol is a biologically active compound that has been identified in a biological sample. It reacts with amyloid protein to form an adduct. The mechanism of this reaction is not yet known. 7-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol has also been found in pueraria lobata and may have biological properties.

Please enquire for more information about 2-(2,5-Dimethylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 6-​Benzyloxy-​7-​methoxy-​3,​4-​dihydro-​isoquinoline is a reactant used in the synthesis of VMAT2 imaging agents. References Liu, C. et al.: Chiral., 25, 215 (2013);

Please enquire for more information about 1-(2-Methoxyethyl)-1H-indole-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-Chloro-2-(5-methylthien-2-yl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4,4,7,8-Tetramethyl-4,5-dihydro-1H-[1,2]dithiolo[3,4-c]quinoline-1-thione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 5-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-[2-(1H-Indol-3-yl)ethyl]-1,3-dioxoisoindoline-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,1'-Bicyclohexyl]-1-carboxylic acid (BCX) is a metal salt that is soluble in water. BCX has a quadratic structure and is a cyclohexanecarboxylic acid derivative. It can be made by the reaction between formic acid and chloride. BCX is used as an anti-diarrheal agent for the treatment of chronic diarrhea. It has been shown to have high entrapment efficiency and high efficiency when synthesized with dicyclomine. This technique uses formic acid as the solvent, which reacts with chloride to produce BCX.

4-Azatricyclo[4.3.1.1~3,8~]undecane hydrochloride is a tricyclic compound that has antiviral, antiinflammatory, and cardiovascular activities. It inhibits the production of leukotrienes from arachidonic acid and has been shown to be a useful treatment for bronchial asthma in animal models. 4-Azatricyclo[4.3.1.1~3,8~]undecane hydrochloride is extracted from the plant Echinops ritro and can be prepared by the intramolecular cyclization of undecane with an azatriene or azetidine ring system as an intermediate step. The reactivity of this molecule has been studied using X-ray analysis on intermediates and trackable products such as methyl vinyl ketone (MVK).

Please enquire for more information about 4-Amino-2-methylquinoline-6-carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 1-(4-Chlorobutyl)-7-hydroxyquinolin-2(1H)-one is a useful research chemical.

Applications 6-Fluoroquinoline, is a versatile building block used in the synthesis of various chemical compounds.

Please enquire for more information about (S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Nitroindole-2-carboxylic ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3,4-Dihydroquinolin-1(2H)-yl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-Methyl-2-oxoindoline-3-oxime including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Butoxyquinoline-4-carboxylic Acid is used in the organic synthesis of o-(β-diethylaminoethyl)cinchoninaldoxime with local anesthetic activity References Rossi, S., et al.: Farmaco, Edizione Scientifica, 34, 486 (1979)

2-(2-(2-Hydroxyethoxy)Ethyl)Isoindoline-1,3-Dione is a chemical compound that belongs to the class of organic compounds. It can be used in the production of Zovirax, an antiviral drug for the treatment of herpes simplex virus. 2-(2-(2-Hydroxyethoxy)Ethyl)Isoindoline-1,3-Dione has been shown to inhibit viral replication by interfering with DNA synthesis and/or by altering the permeability of the cell membrane. This compound also displays strong antiviral activity against a wide range of viruses including herpes simplex virus type 1 and 2, adenovirus, vesicular stomatitis virus, cytomegalovirus (CMV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), influenza A virus, and rotavirus.

Please enquire for more information about 6,7-Dimethoxy-2-methyl-3-[4-(methylthio)phenyl]-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 9-Methyl-2,9-diazaspiro[5.5]undecane including the price, delivery time and more detailed product information at the technical inquiry form on this page