Polycyclic Compounds

Quinoline-8-sulfonamide is a hydrated compound that is used as a matrix metalloproteinase inhibitor. It has been shown to have anticancer activity and blocks the production of matrix metalloproteinases by binding to the active site of these enzymes. Quinoline-8-sulfonamide also inhibits the activation of toll-like receptors, which are proteins found on cells that play a critical role in an inflammatory response. This drug has been shown to inhibit methionine aminopeptidase, an enzyme involved in the metabolism of amino acids. The mechanism of action for this drug is not fully understood, but it is thought to be due to metal ion coordination chemistry and may involve the trifluoromethyl group.

Please enquire for more information about 3-Piperidin-2-yl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-Methoxy-1,2,3,4-tetrahydroquinoline hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Indole-3-acetic acid hydrazide is a molecule that has been shown to inhibit the activity of enzymes such as phosphofructokinase, pyruvate kinase, and lactate dehydrogenase. The compound also inhibits hemolytic activity by binding to the red blood cell membrane and inhibiting the enzyme NADH oxidoreductase. Indole-3-acetic acid hydrazide has been shown to bind to divinylbenzene with a hydrogen bond. The compound is also able to inhibit fatty acid synthesis through its interaction with the fatty acid synthase enzyme. In addition, indole-3-acetic acid hydrazide can be used as an inhibitor of SplA2 in cells.

Applications 1,3-Diiminoisoindoline is a useful compound in the production of colouring compositions. Dyes and metabolites. References Matsumoto, T., et al.: PCT Int. Appl. (2020), WO 2020218262 A1

Please enquire for more information about 7-Chloro-2-(3-chlorophenyl)-8-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (1,2,3,4-Tetrahydroisoquinolin-1-ylmethyl)amine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Methoxyphenyl)-3-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-Chloro-2-(2-ethoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Chloro-8-methyl-2-pyridin-4-ylquinoline-4-carbonyl chloride hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Chloropyrido[2,3-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tert-Butyl 3-bromo-1H-indole-1-carboxylate is a versatile building block that can be used in the synthesis of complex compounds. It is a useful reagent and speciality chemical, as well as a useful intermediate in the production of research chemicals. Tert-Butyl 3-bromo-1H-indole-1-carboxylate has been found to be a useful scaffold for drug design and development, with potential applications in cancer treatment.

Please enquire for more information about 1,5-Dimethyl-1H-indole-2-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Iodo-1-tritylimidazole is an organic molecule that has a chemical stability comparable to that of a nucleophile. It is a molecule with a heterocycle and accepts electrons from carbinol compounds, halides, and other functional groups. 4-Iodo-1-tritylimidazole can be synthesized by the palladium-catalyzed coupling reaction between organometallic reagents and histidine. This compound has been shown to have properties that are similar to those of biomimetic molecules, such as cross-coupling.

Tris(8-quinolinolato)aluminum (purified by sublimation) is a compound that has been purified by sublimation. It is a crystalline solid, which is light sensitive and reacts with water to produce hydrogen gas. The compound's electron affinity, or ability to attract electrons, has been determined using gravimetric analysis. Tris(8-quinolinolato)aluminum (purified by sublimation) is not carcinogenic in rats and mice. It can be used as a low energy electron emitter in the form of free carriers or excitons. This property may lead to its use in the development of optical devices such as lasers and LEDs. Tris(8-quinolinolato)aluminum (purified by sublimation) has also shown potential for use as an inhibitor of corrosion and as a chemical stabilizer.

N,N'-(6-Phenylphenanthridine-3,8-diyl)-bis-ethyl carbamate is a triflate that can be used as an extraction reagent. It has been shown to have a high yield and good solubility in chlorobenzene and other organic solvents. N,N'-(6-Phenylphenanthridine-3,8-diyl)-bis-ethyl carbamate can be used for the preparation of ethidium bromide and some other compounds. The compound was prepared by reacting chlorobenzene with nitrobenzene. Trifluoromethanesulfonic acid was then added to this mixture followed by the addition of hydrobromic acid. Finally, sulfuric acid was added and the reaction was heated at 140°C for 24 hours.

Please enquire for more information about 2-Cyclopropyl-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Bromo-1,3-dichloroisoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-{[2-(Methylamino)quinolin-8-yl]oxy}quinolin-8-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Sodium 1-acetylindoline-2-sulfonate is a nitrated compound that is used in the preparation of alkali metal salts. It is prepared by reacting sodium nitrate with 7-nitroindole. Sodium 1-acetylindoline-2-sulfonate can be used to produce equimolar metal salt of 7-nitroindole with an alkali metal, such as sodium, potassium or lithium. This substance has been used in medicine for the treatment of various conditions and diseases, including tuberculosis and cancer.

Please enquire for more information about Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane is a polymerase that has been developed for use in vaccines and as an agrochemical for the control of plant diseases. This enzyme has been shown to have high activity against cancer cells, including lung cancer cells and breast cancer cells. It is also autofluorescent and can be used as a cell marker in flow cytometry experiments. N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane also has antiinflammatory effects on macrophages by inhibiting the production of proinflammatory cytokines such as IL 12p

Please enquire for more information about 1-(3-Chloropropanoyl)indoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

[(1R,2S,3R,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-3-yl]borane is an excitatory amino acid that is found in the body. The compound has been shown to be a potent and selective agonist of excitatory amino acids of the Glu receptor family. This substance has also been used for the asymmetric synthesis of cyclopentene derivatives with high enantiomeric excesses. It can be synthesized by hydroboration of 2-butyne followed by acidification and decarboxylation.

5-Fluoro-1-Methyl-1H-Indole-3-Carbaldehyde is a high quality chemical that is used as a reagent, an intermediate for the synthesis of pharmaceuticals, and in the production of fine chemicals. 5FMICA is also a useful scaffold for developing valuable building blocks. This chemical has been shown to be a versatile building block for the synthesis of complex compounds. 5FMICA can be used as a reaction component for the preparation of speciality chemicals and research chemicals.

7-Bromo-2,3-dioxoindoline is a synthetic compound with a vibrational frequency of 249.2 cm−1. It is an inhibitor of the enzyme synthetase and has been shown to have an inhibitory effect on cancer cell viability in vitro. 7-Bromo-2,3-dioxoindoline inhibits the production of cancerous cells by interfering with their ability to synthesize DNA, which is necessary for cell division. This inhibition may be due to its ability to form intermolecular hydrogen bonding interactions with the amine group on the enzyme synthetase. 7-Bromo-2,3-dioxoindoline has also been shown to block the synthesis of 5-chloroisatin, one of its reaction products. The bioassay was carried out by measuring the amount of granulosa cells that were able to produce estrogen after treatment with this compound.

4-Chloro-1-phenylpyrazole is a Grignard reagent that reacts with carbinols and aldehydes to form ethyl esters, which are used in the preparation of pharmaceuticals. 4-Chloro-1-phenylpyrazole can be prepared by reacting phenylmagnesium bromide with chloroacetone. This reagent reacts with carbinols and aldehydes to form ethyl esters. It also reacts with iodides to give the corresponding iodides. 4-Chloro-1-phenylpyrazole is commercially available as a white solid that melts at 129°C and boils at 269°C.

Please enquire for more information about 2,3-Dimethyl-1H-benz[e]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Quinoline-2-sulfonic acid is a hydroxide that is used for the preparation of sodium hydroxide solution. Quinoline-2-sulfonic acid reacts with sodium hydroxide and water to form sodium sulfite and hydrogen sulfide, which are soluble in water. It is also used as an analytical reagent for the determination of phosphatase activity in biological samples. The reaction mechanism of quinoline-2-sulfonic acid with sodium hydroxide has been studied using light emission spectroscopy. Quinoline-2-sulfonic acid has shown to be a potential target tissue for cancer therapy because it can be activated by light or other electromagnetic radiation, such as gamma rays and X-rays.

Please enquire for more information about 3-Chloropyrido[2,3-b]pyrazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Research has shown that benzeneacetic acid, a-hydroxy-a-phenyl-, (3-endo)-8-azabicyclo[3.2.1]oct-3-ylester has affinity for muscarinic acetylcholine receptors in the brain and spinal cord. The affinity of this ligand for these receptors is higher than that of acetylcholine. This compound is able to bind to the same receptors as acetylcholine, but with a higher efficiency. These properties make it an interesting candidate as a ligand in the development of new drugs to treat diseases related to the nervous system, such as Alzheimer's disease or Parkinson's disease.

Please enquire for more information about 9-Methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Benzoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5,6,7-Trimethoxy-1H-indole-2-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

7-Amino-5-chloroquinolin-8-ol is a chemical substance that has been quantified by visual and titration techniques. It is also possible to quantify this substance with analytical methods, such as dithionite, which is a technique that is used to determine the concentration of iron in a solution. The sample preparation for this substance should be done with care, as it can react with other chemicals in the environment. This chemical species can be found in 5-chloro-8-hydroxyquinoline or 8-hydroxyquinoline. The parameters for this substance are scalable, and statistical analysis can be used to describe its effects on the human body.

Please enquire for more information about 5-Chloro-3-methyl-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Chloro-3-methyl-1H-indole-2-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1,1'-Diphenyl-4,4'-bipyridinium Dichloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Lactone

1-Methyl-1H-indole-2-carboxylic acid is an organic compound that is classified as an aldehyde. It has the chemical formula CH3CONHCH2CH2COOH. The carboxyl group on this molecule can undergo acid catalysis to form 1-methylindole-2-carboxylic acid, which is an unsubstituted indole. 1-Methylindole-2-carboxylic acid is synthesized from 1-methylindole and 2 equivalents of oxalic acid in the presence of heat and a catalyst. This reaction requires no solvent or reactants other than these two components. The product can be purified by distillation, crystallization, or recrystallization. Reaction with amides leads to the formation of amides, while reaction with aromatic aldehydes leads to the formation of cyclic products. Cyclic products are formed when 1,3,5 trim

Please enquire for more information about 2-Pyridin-2-ylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 1,4-Diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (cas# 119752-83-9) is a useful research chemical.

2-[2-(4-Phenoxy-2-propylphenoxy)ethyl]-1H-indole-5-acetic acid is a model system for the study of cell proliferation and apoptosis. It has shown synergistic effects with other anticancer drugs such as p-nitrophenyl phosphate, which are used to treat cancer. 2-[2-(4-Phenoxy-2-propylphenoxy)ethyl]-1H-indole-5-acetic acid has also been shown to induce apoptosis in squamous cell carcinoma cells in vitro. The mechanism of this effect is not yet clear, but it may involve the activation of caspase 3, which is an enzyme that participates in the proteolytic pathway of apoptosis.

2-Aminoindole hydrochloride is a heterocyclic amine that is formed by the reaction of benzene and an aminoindole. It is a difunctional compound that can react with alcohols to form amides, carbonyl groups to form ketones, or carbamate groups to form ureas. This compound has been shown to act as an activated aromatic amine that reacts with oxygen in the atmosphere to form a variety of products, including chlorinated aromatic amines. 2-Aminoindole hydrochloride has been shown to have carcinogenic effects in rats when administered orally at high doses.

Please enquire for more information about 8-Methyl-1-thia-4,8-diazaspiro[4.5]decane-3-carboxylic acid dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 3-bromo-5-methyl-1H-indole-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Chlorophenyl)-3,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(1,3-Benzodioxol-5-yl)-6,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Fluoro-2-phenylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Amino-6,8-dimethylquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

3,3'-Dihydroxy-2,2'-bipyridine is a water-soluble drug that has been shown to be cytotoxic. It binds to the hydroxyl group of hemoglobin and prevents it from binding with oxygen. 3,3'-Dihydroxy-2,2'-bipyridine also binds to the cell membrane and enters the cell where it forms a cavity with a chelate ring. The molecule has been shown to have high photophysical properties and can be used in biological studies.

1-Benzyl-1H-indole-2-carboxylic acid is a molecule that binds to chemokine receptors and has been used in screening assays as a chemical probe of chemokine receptor binding. It has been shown to be an antagonist of the CXCR3 receptor, with high affinity and selectivity. 1-Benzyl-1H-indole-2-carboxylic acid is also an antagonist of the CCR5 receptor, with low affinity. This compound was discovered by screening for novel antagonists of chemokines.

Please enquire for more information about Calipteryxin including the price, delivery time and more detailed product information at the technical inquiry form on this page

1H-Indole-5-carboxamidine is a compound with a hydroxyl group. It has been shown to inhibit the activity of serine protease and coagulation factors, which are important for coagulation. 1H-Indole-5-carboxamidine also inhibits the activity of urokinase-type plasminogen activator, an enzyme that breaks down blood clots. This drug has been shown to inhibit the formation of blood clots in both animal and human studies. The molecular modeling study revealed that 1H-indole-5-carboxamidine binds to benzamidine, a substrate of serine proteases, through hydrogen bonding interactions and chlorine atom. This binding prevents the substrate from interacting with urokinase type plasminogen activator (uPA) and prevents it from cleaving prothrombin to form thrombin, leading to inhibition of coagulation.

5-Hydroxyindole-2-carboxylic acid is a chemical species that belongs to the group of p-hydroxybenzoic acids. It is an intermediate in the synthesis of dopamine and melanin. 5-Hydroxyindole-2-carboxylic acid has been shown to inhibit the growth of cancer cells in vitro, which may be due to its ability to promote apoptosis. This compound also inhibits the production of eumelanin, which is responsible for black pigmentation in mammals. 5-Hydroxyindole-2-carboxylic acid has been shown to have anti-cholinergic properties and can be used for the treatment of chronic schizophrenia. 5HICA has also shown to have antioxidant properties due to its ability to reduce reactive oxygen species (ROS) and lipid peroxidation.

Chelating agent used to detect aqueous copper ions by electrochemiluminescence

7-Bromo-2-chloroquinoline is an analog of quinoxaline. It is a potent antitumor agent that inhibits DNA synthesis and has been shown to be effective in treating solid cancers in both human and animal models. 7-Bromo-2-chloroquinoline binds to the putative target site on tumor cells, which is located on the surface of cancer cell lines, and inhibits the enzyme that catalyzes the conversion of phenylalanine to tyrosine. This enzyme is required for DNA synthesis and its inhibition leads to a decreased rate of cell division. The heterocyclic ring in this drug may react with DNA, resulting in cross linking and chain termination.

Please enquire for more information about 6-Chloro-2-(3-isobutoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Chloroquinolin-6-amine is a synthetic compound that is used in the study of bacterial cell wall synthesis. It has been shown to react with transition metal ions, such as copper, and radionuclides, such as technetium 99m (Tc99m), to form complexes that can be used as radiotracers. 2-Chloroquinolin-6-amine binds to amines and other nucleophilic compounds. This property has been exploited to synthesize positron emission tomography (PET) imaging agents for use in the diagnosis of resistant bacterial infections. The nitro group on this molecule also makes it reactive, which can result in DNA damage and cell death.

Please enquire for more information about 5-(3-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page