Polycyclic Compounds

Please enquire for more information about 9-Fluoro-10,13,17-Trimethyl-2,3,4,5,6,7,8,11,12,14,15,16-Dodecahydro-1H-Cyclopenta[a]Phenanthrene-3,11,17-Triol including the price, delivery time and more detailed product information at the technical inquiry form on this page

7,8-Dihydroquinoline-2,5(1H,6H)-dione is a synthetic compound that belongs to the group of lactams. It is cyclic and has two amide groups. This drug is used as an antiinflammatory agent in the treatment of rheumatoid arthritis and other inflammatory disorders. 7,8-Dihydroquinoline-2,5(1H,6H)-dione has been shown to inhibit the growth of malaria parasites in vitro by inhibiting the activity of enaminone reductase. The drug also inhibits trypsin activity by binding to carboxylate side chains on the enzyme's surface.

4-Aminoindole is a heterocycle with a carboxy group and four nitrogen atoms. It can be synthesized by reacting hydrochloric acid with nitrobenzene. 4-Aminoindole has shown potential as a drug target, which may be due to its ability to inhibit the enzyme carboxamidase. The compound is also acidic in water, making it an ideal candidate for use as an acid catalyst. Electropolymerization of 4-aminoindole has been achieved using Pt electrodes in the presence of an acidic environment. This reaction results in the formation of functional groups on the metal surface that are not found in most other electropolymerization reactions.

Please enquire for more information about N-Cyclohexyl-2,3-dioxoindoline-5-sulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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2-Trifluoromethylindole is a synthetic chemical that is used as an intermediate to synthesize other chemical compounds. It is obtained by reacting anilines with acid catalysts in the presence of chloride and methyl proton, followed by isolation of the product. The reaction yields 2-trifluoromethylindole with an isolated yield of about 75%. This compound has been shown to be efficient in the palladium-catalyzed coupling reaction between phenyl derivatives and 5-hydroxytryptamine (5-HT)6 receptor ligands.

Please enquire for more information about 7,8-Difluoroquinoline-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline is a chemical compound that has been used as an intermediate in the synthesis of pharmaceuticals. It is also a useful building block for the production of other chemicals. This compound is soluble in water. 1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline has shown to be a versatile and high quality reagent with many research applications.

5-Amino-1-phenylpyrazole is a heterocyclic amine with insecticidal activity. It has been shown to be effective against larvae of the cabbage butterfly, Pieris rapae. The mode of action may be due to inhibition of cholinesterase activity in the insect's nervous system. 5-Amino-1-phenylpyrazole also has fluorescence properties and can be used as a fluorescent probe for detecting reaction mechanism.

Please enquire for more information about 1-(2-Bromobutanoyl)indoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Stability Hygrscopic Applications 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt

Please enquire for more information about 6-Bromo-1-[(1S)-1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-methylpropyl]-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic a cid ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-Chloro-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-2-(2-thienyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Benzyl-2,2,4-trimethyl-1,2-dihydroquinoline-6-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6,8-Dimethyl-2-pyridin-2-ylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 4-(aminomethyl)-1H-indole-1-carboxylate hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Benzyl-2,5-diaza-bicyclo[2,2,1]heptane including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 2-(1H-Imidazol-1-yl)-8-nitroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile is a microalgal extract that has been shown to inhibit acyltransferases and diode radiation. It also has the ability to alter fatty acid profiles. The optical sensor can detect the presence of unprocessed 5-[4-[6-(2,2,2-trifluoroethyl)-thieno[2,3-d]pyrimidin-4-yl]-amino]-1-[(piperidinomethyl)] indole 2 carbonitrile in a sample. Speckles are produced from the device as it analyzes the fatty acid profile.

Please enquire for more information about Ethyl 3,5-dimethyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl 9-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Acetylindole is a synthetic compound that has been shown to have anticancer activity. It inhibits the growth of cancer cells by disrupting their mitochondria, which leads to cell death. 5-Acetylindole was synthesized in an attempt to increase the anticancer efficacy of indole compounds and acetylation of indole rings was found to be an effective strategy for this purpose. Acetylation of the 5 position on the indole ring leads to a more potent antiproliferative agent with decreased potential for resistance development. This compound has been shown to disrupt cellular function in k562 cells, leading to cell death.

Please enquire for more information about 2-Amino-N-(3-chlorophenyl)quinoline-3-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Amino-3-(1.2-dihydro-2-oxoquinoline-4-yl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Methylimidazole is a crystalline solid that has been used in the preparation of coordination compounds. The compound is prepared by reacting 2-methylimidazole with an appropriate metal cyanide, such as copper cyanide or nickel cyanide. The crystal structure of 2-methylimidazole shows strong hydrogen bonding interaction between the nitrogen atoms and the carboxylate groups. This compound has been used in clinical pathology to detect increased levels of ammonia, uric acid, and lactic acid in the blood. 2-Methylimidazole is not toxic to humans but has shown some toxicity to mice when injected intravenously at high concentrations. It can be used as an analytical method for determining trace amounts of chlorine in chemical compounds by way of electrochemical impedance spectroscopy (EIS).

Please enquire for more information about 2-(1,3-Benzodioxol-5-yl)-6,8-dimethylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 5-Fluoro-2-oxindole (cas# 56341-41-4) is a compound useful in organic synthesis.

N-Pentylindole is a ligand that binds to cannabinoid receptors. It has a carbonyl group and can be demethylated in vivo to form N-pentylpiperidine. N-Pentylindole is structurally similar to the synthetic cannabinoid JWH-018 and has been shown to have affinity for CB1 and CB2 receptors. Drug preparations of N-pentylindole are typically dehydrogenated, which leads to the formation of carboxylic acids, amides, or esters. These derivatives have shown effects on the binding of N-pentylindole at cannabinoid receptors.

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5-Amino-2-methylindole is a hyaluronic acid inhibitor that has been shown to have an inhibitory effect on the growth of some bacteria. It inhibits the synthesis of bacterial enzymes and growth factors, which are required for bacterial cell division. 5-Amino-2-methylindole also inhibits the production of a number of important enzymes in bacteria, including benzofuran derivatives, as well as p. aeruginosa. This drug is used as a topical treatment in cases where there is tissue damage or inflammation. 5-Amino-2-methylindole has been shown to be effective against gram positive bacteria such as Streptococcus pyogenes and Enterococcus faecalis, but not against gram negative bacteria such as Pseudomonas aeruginosa or Escherichia coli.

Reduces brain amyloid plaques; induces neprilysin expression

Please enquire for more information about 3-Amino-5-bromo-1H-indole-2-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Phenyl-1H-indole-2,3-dione is a crystalline polymorph that has been shown to have a binding constant in the range of 1.5 x 10^7 M^−1. It also has an emission spectrum that peaks at 478 nm and a quantum yield of 0.25. 1PHI2D has been used as a synchronous fluorescence quencher for polycarbonates with absorbers, such as zinc sulfide and cadmium selenide, with absorption maxima in the range of 300-400 nm. 1PHI2D has been found to modulate the coloration of dyes in animals. It has also been shown to be an effective anti-depressant and can be used as a hydrogen bond donor or acceptor. This molecule is also known to bind to the CB2 receptor.

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Please enquire for more information about 6-Chloro-9-(2-O-acetyl-5-O-(p-toluoyl)-3-azido-3-deoxy-beta-D-ribofuranosyl)-9H-purine including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Methyl-1H-indole-5-carbonitrile is a synthetic anticancer agent that inhibits the growth of cancer cells by binding to DNA. It has been shown to be cytotoxic in cell lines, and is an inhibitor of protein synthesis. This drug can also inhibit cell growth and induce apoptosis in cells. 1-Methyl-1H-indole-5-carbonitrile can be synthesized using a number of different strategies, including pyrazol, imidazole, and cyclopenta. The drug binds to DNA in the form of a covalent bond, inhibiting the replication and transcription of DNA. In addition, 1-methyl indole carbonitrile has been shown to inhibit protein synthesis by binding to ribosomes and preventing the formation of peptide bonds between amino acids.

Applications 2-Chloro-6-(2-hydroxybenzylamino)-9-isopropylpurine (cas# 500568-72-9) is a compound useful in organic synthesis.

6-Bromo-1H-indole-2-carbaldehyde is a potential therapeutic for bacterial infections. It inhibits the growth of bacteria by binding to their DNA and preventing transcription and replication. 6-Bromo-1H-indole-2-carbaldehyde is also an antibacterial agent that binds to the beta subunit of bacterial ribosomes, inhibiting protein synthesis. This drug has been shown to be effective against methicillin resistant Staphylococcus aureus (MRSA) and has been optimized for activity against Gram negative bacteria such as Escherichia coli. 6BRICA can also inhibit serotonin reuptake, which may have antidepressant effects.

Indole-7-methanol is a flavin cofactor that catalyses the formylation of indole-7-carboxylic acid. Indole-7-methanol can be synthesized by the conversion of indole-7-carboxaldehyde with formaldehyde and ammonium acetate. The macrocyclic, isomeric, and formylated forms of indole-7-methanol have been shown to have utilisation activity in the synthesis of various compounds. These reactions are catalyzed by flavins such as FAD or FMN. Mutant, unsymmetrical derivatives of indole-7-methanol are also known to undergo these types of reactions. The most common derivative is indirubin, which has been shown to inhibit DNA polymerase III and IV in vitro.

5-Chloroindole-2-carboxylic acid is a fatty acid that is synthesized from glucose. It has been shown to have inhibitory properties against the enzyme cyclooxygenase-2 (COX-2), which may be due to its ability to suppress prostaglandin synthesis. 5-Chloroindole-2-carboxylic acid also has been shown to have anticancer properties and can inhibit cancer cell growth in vitro. The drug may also play a role in the central nervous system, as it has been shown to cause neuronal death. 5-Chloroindole-2-carboxylic acid is not water soluble, so it must be dissolved in organic solvents such as cyclohexane or chloroform before being used for chemical reactions. This drug can be used with other drugs that are coxib sensitive, such as aspirin, acetaminophen, and ibuprofen.

Please enquire for more information about 8-Chloro-2-(2-methoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about [(4-Isobutyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio]acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

9-Phenanthryl)methyl methacrylate is a fluorescent pigment that is used as a nanomaterial. It is an acidic material and can be used in coatings to improve the properties of materials. 9-Phenanthryl)methyl methacrylate has been shown to have fluorescence resonance energy transfer (FRET) properties, which may be due to its monolayer structure and chromophore. The diameter of this particle ranges from 10-20 nm, with a water permeability of 20% at pH 7.0 and 0.1% at pH 2.0. This pigment has a high degree of surface roughness, which is due to its morphology and the microenvironment in which it exists.

4-(Hydroxymethyl)-1H-indazole is a synthetic compound that has been synthesized by using a surface methodology technique. This technique is based on the principles of x-ray diffraction and electron microscopy. The optimized conditions for the synthesis are ethyl acetate, irradiation with an electron beam and energy-dispersive x-ray spectroscopy. 4-(Hydroxymethyl)-1H-indazole has been shown to have catalytic properties in addition to fluorescence properties, which can be used for fabricating materials with the help of the aforementioned techniques.

2-(5-But-3-yn-2-yloxy-4-chloro-2-fluoro-phenyl)-4,5,6,7-tetrahydroisoindole-1,3-dione (BZ) is a potent inhibitor of microbial growth. It inhibits the synthesis of fatty acids in bacteria and has been shown to be highly toxic to some fungi. BZ has also been shown to inhibit the growth of Vibrio cholerae, Escherichia coli, Bacillus subtilis, and Pseudomonas aeruginosa. It also inhibits the activity of herbicidal and antimicrobial agents in plants.

Please enquire for more information about 5,7-Dimethyl-2-oxo-1,2-dihydroquinolin-8-yl acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

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N-[6-Methoxy-4-Methyl-5-[3-(Trifluoromethyl)Phenoxy]Quinolin-8-Yl]Pentane-1,2-Diamine is a natural product that is an inhibitor of the pyrimidine biosynthesis. It binds to the enzyme dehydrogenase, which is a component of the electron transport chain. This binding prevents the transfer of electrons and leads to cell death. N-[6-Methoxy-4-Methyl-5-[3-(Trifluoromethyl)Phenoxy]Quinolin-8-Yl]Pentane-1,2-Diamine has been shown to be effective in preventing malaria in rhesus monkeys and humans when given prophylactically.