Polycyclic Compounds

Please enquire for more information about 3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5,6,7-Trimethoxy-1-methyl-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Bromo-8-nitroisoquinoline is a drug that binds to the nicotinic acetylcholine receptor and has been shown to have antifilarial activity. It also has an affinity for dopamine receptors in the brain, which may be responsible for its neurological effects. 5-Bromo-8-nitroisoquinoline is a racemic mixture of two enantiomers, one of which is more active than the other. The inactive enantiomer (5-bromo-8-nitroisoquinoline) has a lower affinity for the nicotinic acetylcholine receptor and thus does not show antifilarial activity. This drug is metabolized by liver enzymes to form hydrogenated metabolites with acanthocheilonema worms. The active enantiomer (5-bromo-8-nitroisoquinoline) inhibits dopamine release from nerve cells and prevents them from stimulating muscles, leading to paralysis of these worms

Please enquire for more information about 6,7,8,9,10,11,12,13,14,15-Decahydrocyclododeca[b]quinoline-16-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Chloro-2-(5-ethyl-2-thienyl)-8-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Oxa-6-azaspiro[3.5]nonane oxalate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Ethyl-7-methyl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Phenyl-1H-indazole is a synthetic antibiotic that has been shown to be effective against methicillin resistant Staphylococcus aureus (MRSA) in a study. 5-Phenyl-1H-indazole is an inhibitor of bacterial topoisomerase, which is an enzyme necessary for DNA replication. It binds to the enzyme and prevents it from performing its function, inhibiting DNA synthesis and cell division. This drug has been shown to have antibacterial activity against other bacteria as well, such as Salmonella enterica serovar Typhi and Mycobacterium tuberculosis. 5-Phenyl-1H-indazole has been shown to inhibit bacterial gyrases at nanomolar concentrations, which may be due to its ability to bind to the enzyme's active site.

Please enquire for more information about 3-(3,4-dimethoxyphenyl)-4-(hydroxyimino)-1,6,6-trimethyl-5,6,7-trihydro1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 11-oxo-6,8,9,11-tetrahydro-7H-pyrido[2,1-b]quinazoline-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (8-Fluoroquinolin-3-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Chloro-6-methyl-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tetronic acid is a chemical compound with the molecular formula HOOC(CH)COOH. Tetronic acid can be found in plants and has been shown to have pro-inflammatory cytokines. It also has an active methylene group, which is a reactive molecule that binds to receptors on cells. In addition, tetronic acid has nitro and hydroxyl groups, which are organic molecules that can act as electron donors or acceptors. Tetronic acid can be found in many different forms, including aliphatic hydrocarbons (methane), alkylthios (methyl mercaptan), and carbonyls (acetaldehyde). Tetronic acids are also found in cellular organelles such as mitochondria and lysosomes. They regulate the synthesis of proteins by controlling the flow of amino acids into protein chains. Finally, tetronic acid is known to act as a growth factor for cells.

Please enquire for more information about N',N'-Dimethylindole-2-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3,4-Dimethylphenyl)-6-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications tert-​Butyl 5-​(4,​4,​5,​5-​tetramethyl-​1,​3,​2-​dioxaborolan-​2-​yl)​isoindoline-​2-​carboxylate is a reactant in the synthesis of tyrosine kinase inhibitors in the treatment of proliferative diseases. References WO Patent 2014089324 (2014); CN 104016979 (2014);

Please enquire for more information about 9-Benzyl-6-oxa-9-azaspiro[3.6]decan-8-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about [(2-Methylquinolin-4-yl)methyl]amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(4-Methylbenzyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(8-ChloroisoQuinolin-3-yl)-6-phenyl-1,3,6,2-dioxazaborocane including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about trans,trans-4-(4-Fluorophenyl)-4'-propylbicyclohexyl including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II. References Wu, S., et al.: J. Med. Chem., 54, 2668 (2011);

Please enquire for more information about Moluccanin including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Methoxyphenyl)-6-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Cyclopropylquinoline-4-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone is a molecule that is found in plasma samples and has been shown to inhibit the growth of cells. It is a potent inhibitor of tubulointerstitial injury, which is the most common type of kidney disease. The mechanism of this drug has been shown to involve the inhibition of primary amino acid uptake. This compound also inhibits urea synthesis and decreases plasma concentrations by increasing the rate of elimination. In addition, it has been shown to have an inhibitory effect on growth factors such as EGF, bFGF, IGF-1, and PDGF. N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone can be synthesized by heating at high temperatures (thermally activated).

4-Bromo-2,2'-bipyridine is a bidentate ligand that can be used as a catalyst to facilitate the Suzuki-Miyaura coupling of styrene and olefins. It has been shown to react with cyclopentadiene in an electrochemical system to form a dimerization product. 4-Bromo-2,2'-bipyridine has photophysical properties that are sensitive to substituents and structural changes. The ligand absorbs light at wavelengths in the range of 400 nm to 700 nm due to its mononuclear structure and bidentate nature.

Please enquire for more information about (6aS,7aR,8S,11aR,12aS)-5,6a,7,7a,8,9,11a,12a-Octahydro-4,8,11,11a,13-pentahydroxy-12a-methyl-5,9-dioxo-6,8-methano-6H-benzo[c]xanthe ne-10-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Cyano-1,2,3,4-tetrahydroquinoline is a synthetic intermediate that is used in the synthesis of heterocyclic compounds. It is a quinoline derivative that can be used as a brominating agent. 6-Cyano-1,2,3,4-tetrahydroquinoline has been shown to be an effective catalyst for the synthesis of chloride derivatives and yields high yields when used in the production of tetrahydroquinoline.

Applications 4,4-difluoro-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 1443981-83-6) is a useful research chemical.

1-Isopropyl-3-(4-fluorophenyl)indole is a solvent that has been shown to be useful for the deuterium enrichment of carbonyl compounds. It is also used as a reagent for the Friedel-Crafts acylation and for the synthesis of 3-methoxyacrylate. The process of wastewater treatment is made more efficient by adding 1-isopropyl-3-(4-fluorophenyl)indole to chloride. This process increases yields and decreases the amount of time it takes to complete wastewater treatment. 1-Isopropyl-3-(4-fluorophenyl)indole can also be used in the synthesis of fluvastatin, an antilipidemic agent.

Please enquire for more information about 2-(4-Ethoxyphenyl)-6,8-dimethylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Acetylindole is a dibenzopyran compound that has been shown to have anti-inflammatory properties. 3-Acetylindole inhibits the acylation reaction of arachidonic acid with coenzyme A and thereby blocks the production of prostaglandin E2. This compound also binds to the benzene ring, which may be due to its acidic nature. 3-Acetylindole has been shown to inhibit T-cell leukemia and other cancers in animal models. It has also been shown to inhibit the growth of cancer cells in culture by blocking DNA synthesis and inhibiting proliferation. The binding constants for this compound have been determined by x-ray crystal structures and protonation studies.

Please enquire for more information about 7-Bromo-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-fluoro-6-methoxy-1h-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(Cyclopropylcarbonyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4,4,6-Trimethyl-1,2-dioxo-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-8-yl 3-fluorobenzoate including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,5-Dimethyl-1H-indole is a dipole that can be synthesized using a phenylhydrazone as an intermediate. It has been used to treat inflammatory diseases by inhibiting the activity of leukocytes and other inflammatory cells. 2,5-Dimethyl-1H-indole is also known to inhibit the synthesis of prostaglandins. The condensation products of 2,5-dimethyl-1H-indole have been shown to be effective in the treatment of asthma and other respiratory disorders. The linear response of 2,5-dimethyl-1H-indole makes it an ideal chromatographic agent for the detection of small quantities of molecules. The chemical structure and UV absorption properties make 2,5-dimethyl-1H-indole a useful synthetic intermediate in various chemical processes.

4-Methyl-N-(3-piperidin-1-ylpropyl)-6-(trifluoromethyl)furo[4,5-b]indole-2-carboxamide is a potent inhibitor of the enzyme COX that is used in the treatment of inflammation and pain. This drug has been shown to inhibit the formation of prostaglandins, which are hormone-like substances that contribute to inflammation and pain. It also has an inhibitory effect on dyslipidemia and insulin resistance, but it does not have an effect on platelet aggregation or bleeding time.

Please enquire for more information about N-(4,6-Dimethylpyrimidin-2-yl)-3,4-dihydroquinoline-1(2H)-carboximidamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Methylindazole-5-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-7-methyl-5-nitroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Bromo-1-(2-phenylethyl)-1H-indole-2,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6'-Methyl-5',6'-dihydrospiro[cyclohexane-1,4'-pyrrolo[3,2,1-ij]quinoline]-1',2'-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Chloro-2-methylene-1,3,3-trimethylindoline is a covalent inhibitor that binds to the response pathway. This drug has been shown to have clinical activity in cardiac and cancer patients. It has also been used as a diagnostic agent for diagnosis of tumors and other diseases. The mechanism of action of this drug is not well understood but it is believed that the cleavage products may be diagnostic. In addition, 5-chloro-2-methylene-1,3,3-trimethylindoline has structural homologues with drugs such as cisplatin, which are used in chemotherapy treatments for cancer.

Please enquire for more information about 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside) (cas# 39824-26-5) is a compound useful in organic synthesis.

Please enquire for more information about Tetraethyl 5',5',9'-trimethyl-5',6'-dihydrospiro[1,3-dithiole-2,1'-thiopyrano[2,3-c]quinoline]-2',3',4,5-tetracarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 9,9-Dimethyl-xanthene-3,6-diol has been used in the manufacturing of dihydroxydiaminoxanthenes as monomers for positive-working resists by treatment of dihydroxybenzenes with carbonyl compounds, nitration, and reduction. References Sumitani, N.; et al.: Jpn. Kokai Tokkyo Koho 13 pp. Patent 2004 CODEN:JKXXAF

Please enquire for more information about 2-(4-Isopropoxyphenyl)-8-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

7-Bromo-1-hydroxyisoquinoline is an organic compound that can be synthesized by reacting 1,2-dihydroxyisoquinoline with bromine and a radical initiator. It has been shown to be a regioselective inhibitor of lipid peroxidation that produces a high yield of the desired product. 7-Bromo-1-hydroxyisoquinoline was first synthesized in the 1940s and has been used as a synthetic tool for fluorinating various organic compounds.

Please enquire for more information about 1-Ethyl-1H-indole-5-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Methyl-2-pyridin-2-ylquinoline-4-carbonyl chloride hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Stability Moisture Sensitive Applications 1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-sulfonyl chloride (cas# 1240529-56-9) is a useful research chemical.

Please enquire for more information about 5-Methyl-1h-indazole-6-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 7-azaspiro[3.5]nonan-2-ylcarbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Amino-1-Cyclopropyl-6,7-Difluoro-8-Methyl-4-Oxo-1,4-Dihydro-3-Quinolinecarboxylic Acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Methylspiro[1,3-dioxane-2,2'-tricyclo[3.3.1.1~3,7~]decane]-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Chloro-6-iodoquinoline is a quinoline derivative that has been used as a building block in organic synthesis. It is typically prepared by the reaction of an acid chloride with chlorine or by chlorination of an aromatic ring. The compound has been used in cross-coupling reactions, halogenation, and crystallography. 4-Chloro-6-iodoquinoline can be prepared from dimethylacetylenedicarboxylate and chlorides or halides. This product can also be synthesized using the Suzuki reaction.

Please enquire for more information about 6-Bromo-2-(3-isopropoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page